# Shankhpushpi (Convolvulus pluricaulis)

**Canonical URL:** https://ingredients.hermeticasuperfoods.com/ingredients/shankhpushpi-convolvulus-pluricaulis
**Data Source:** Hermetica Superfoods Ingredient Encyclopedia
**Updated:** 2026-03-18
**Evidence Score:** 4 / 10
**Category:** Ayurveda
**Also Known As:** Convolvulus pluricaulis, Aloe weed, Bindweed, Speedy weed, Morning glory, Medhya rasayana, Aparajita

## Overview

Shankhpushpi (Convolvulus pluricaulis) is an Ayurvedic herb containing bioactive compounds like convolamine and scopoletin that enhance [cognitive function](/ingredients/condition/cognitive). It works primarily by increasing acetylcholine levels in the brain and modulating GABA receptors to improve memory and reduce anxiety.

## Health Benefits

- Shankhpushpi enhances [cognitive performance](/ingredients/condition/cognitive) by improving memory and learning capabilities, making it ideal for academic and professional success. It works by increasing acetylcholine levels in the brain. - It reduces anxiety and stress by calming the nervous system, promoting mental tranquility. - Shankhpushpi supports [sleep quality](/ingredients/condition/sleep) by acting as a natural sedative, helping to regulate sleep cycles. - It boosts [skin health](/ingredients/condition/skin-health) by reducing acne and blemishes, thanks to its [anti-inflammatory](/ingredients/condition/inflammation) properties. - The herb enhances digestion by stimulating [digestive enzyme](/ingredients/condition/gut-health)s, reducing bloating and discomfort. - Shankhpushpi supports heart health by lowering [blood pressure](/ingredients/condition/heart-health) and improving circulation, contributing to cardiovascular wellness. - It improves hair health by nourishing the scalp and strengthening hair roots, reducing hair fall.

## Mechanism of Action

Shankhpushpi increases acetylcholine levels by inhibiting acetylcholinesterase enzyme activity, enhancing cholinergic neurotransmission crucial for memory formation. The herb's alkaloids convolamine and convolvine modulate GABA receptors, producing anxiolytic effects. Scopoletin and other phenolic compounds provide [neuroprotective](/ingredients/condition/cognitive) benefits by reducing [oxidative stress](/ingredients/condition/antioxidant) and [inflammation](/ingredients/condition/inflammation) in neural tissues.

## Clinical Summary

Human studies on shankhpushpi are limited, with most research consisting of small-scale trials with 30-60 participants. A 2014 study showed 40% improvement in memory scores after 30 days of 500mg daily supplementation. Animal studies demonstrate significant [cognitive enhancement](/ingredients/condition/cognitive) and stress reduction, but larger randomized controlled trials in humans are needed. Current evidence suggests promise but requires more robust clinical validation.

## Nutritional Profile

Shankhpushpi (Convolvulus pluricaulis) is not typically consumed as a food source for macronutrient value; it is used as a medicinal herb, and its significance lies primarily in its bioactive phytochemical composition rather than caloric or macronutrient content. Key compounds include: **Alkaloids:** Shankhpushpine, convolvine, convolidine, convosine, and subhirsine (estimated 0.2–0.5% of dry weight), which are believed to modulate [neurotransmitter activity](/ingredients/condition/cognitive), particularly acetylcholine and GABA pathways. **Flavonoids:** Kaempferol (~0.05–0.1% dry weight) and quercetin glycosides, contributing antioxidant and neuroprotective effects; bioavailability of flavonoids is moderate and enhanced when taken with lipids or piperine. **Triterpenoids:** Shankhpushpine-related triterpenoid saponins and β-sitosterol (~0.03–0.08%), which contribute to anxiolytic and [anti-inflammatory](/ingredients/condition/inflammation) activity. **Glycosides:** Scopoletin (a coumarin glycoside, ~0.01–0.04%), contributing to sedative and antispasmodic properties. **Phenolic acids:** Including chlorogenic acid and caffeic acid derivatives (combined ~0.1–0.3% dry weight), with moderate oral bioavailability acting as [free radical scaveng](/ingredients/condition/antioxidant)ers. **Fatty acids/Lipids:** The seeds contain small amounts of linoleic acid and oleic acid. **Minerals (per 100 g dry herb, approximate):** Calcium (~180–250 mg), Iron (~8–15 mg), Magnesium (~60–90 mg), Zinc (~2–4 mg), Potassium (~350–500 mg), Phosphorus (~50–80 mg). **Vitamins:** Trace amounts of Vitamin C (~5–12 mg/100 g fresh herb) and small amounts of B-complex vitamins (particularly riboflavin and niacin in trace quantities). **Fiber:** Crude fiber content approximately 15–22% of dry weight (mostly insoluble). **Protein:** Approximately 5–8% of dry weight, not a significant dietary source. **Other bioactives:** D-glucose, rhamnose, and starch-based polysaccharides that may serve as [prebiotic](/ingredients/condition/gut-health) substrates. **Bioavailability notes:** The alkaloids and flavonoids in Shankhpushpi have moderate oral bioavailability; traditional Ayurvedic preparations (e.g., as a kashayam/decoction or with ghee — ghrita formulation) are designed to enhance lipophilic compound absorption. Aqueous and hydroalcoholic extracts are the most studied forms, with peak plasma levels of key alkaloids typically reached within 1–3 hours post-ingestion. Co-administration with healthy fats or piperine (from black pepper) may significantly improve absorption of triterpenoids and flavonoids.

## Dosage & Preparation

Shankhpushpi is typically taken in capsule or powder form, with dosages ranging from 250 mg to 500 mg per day. Consult a healthcare provider before use.

## Safety & Drug Interactions

Shankhpushpi is generally well-tolerated with mild side effects including occasional drowsiness or gastrointestinal upset in sensitive individuals. It may enhance the effects of sedative medications and anticonvulsants due to its GABAergic activity. Safety during pregnancy and lactation has not been established, so use should be avoided. Diabetic patients should monitor [blood glucose](/ingredients/condition/weight-management) as the herb may have hypoglycemic effects.

## Scientific Research

Some studies suggest Shankhpushpi may enhance [cognitive function](/ingredients/condition/cognitive) and reduce stress, but more research is needed to confirm these effects.

## Historical & Cultural Context

Shankhpushpi has been used for centuries in Ayurvedic medicine as a medhya rasayana, valued for its potential to enhance [mental clarity](/ingredients/condition/cognitive) and reduce anxiety.

## Synergistic Combinations

Brahmi, Ashwagandha, Gotu Kola

## Frequently Asked Questions

### What is the recommended dosage of shankhpushpi for memory enhancement?

The typical dosage ranges from 500-1000mg of standardized extract daily, or 3-6 grams of powder divided into two doses. Clinical studies have used 500mg daily with significant cognitive improvements observed after 4 weeks of consistent use.

### How long does shankhpushpi take to show cognitive benefits?

Initial cognitive improvements may be noticed within 2-3 weeks of regular use, with optimal benefits typically achieved after 4-6 weeks. Memory enhancement and anxiety reduction effects are cumulative and require consistent daily supplementation.

### Can shankhpushpi be taken with other nootropic supplements?

Shankhpushpi can generally be combined with other cognitive enhancers like brahmi or ginkgo biloba, but dosages may need adjustment. Avoid combining with prescription cognitive medications without medical supervision due to potential additive cholinergic effects.

### What are the active compounds responsible for shankhpushpi's brain benefits?

The primary bioactive compounds include convolamine and convolvine (alkaloids), scopoletin (coumarin), and various phenolic acids. Convolamine specifically inhibits acetylcholinesterase while scopoletin provides antioxidant neuroprotection.

### Is shankhpushpi effective for ADHD or attention disorders?

While traditional use suggests benefits for attention and focus, clinical evidence for ADHD treatment is limited to preliminary studies. Some research indicates improved concentration and reduced hyperactivity, but it should not replace conventional ADHD treatments without medical guidance.

### Is shankhpushpi safe to take during pregnancy and breastfeeding?

Shankhpushpi is traditionally considered safe, but clinical evidence specifically for pregnancy and breastfeeding is limited. Pregnant and breastfeeding women should consult with a healthcare provider before use, as some constituents may cross the placental barrier or transfer into breast milk. Most practitioners recommend avoiding shankhpushpi during these periods unless explicitly recommended by a qualified medical professional.

### Does shankhpushpi interact with common psychiatric medications like SSRIs or anti-anxiety drugs?

Shankhpushpi may interact with SSRIs and benzodiazepines due to its effects on neurotransmitters and CNS activity, potentially causing additive sedation or serotonergic effects. Anyone taking psychiatric medications should consult their doctor before combining with shankhpushpi to avoid adverse interactions. Blood pressure medications may also be affected given shankhpushpi's calming properties.

### What is the most bioavailable form of shankhpushpi—powder, extract, or standardized capsule?

Standardized extracts and concentrated decoctions offer superior bioavailability compared to raw powder due to enhanced absorption of active alkaloids like scopoletin and tropane alkaloids. Ayurvedic practitioners traditionally prepare shankhpushpi as a fresh juice or ghee-based formulation to maximize therapeutic efficacy. Modern capsules with standardized extract content provide consistent dosing, though traditional preparation methods may offer synergistic benefits from the whole plant matrix.

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