Evidence-Based Guide

Gut Health & Digestion

Prebiotic, probiotic, and gut-healing compounds that support microbiome diversity, intestinal barrier integrity, and digestive function.

20ingredients ranked by evidence
#1

Turmeric Leaf Extract

Strong
Leaf/Green

Rich in curcuminoids and flavonoids, turmeric leaf extract reduces oxidative stress, supports cellular repair, and mitigates inflammation; Contains essential oils like turmerone and zingiberene that stimulate bile production, improve gut microbiota, and reduce bloating; Exhibits antimicrobial and expectorant properties, supporting lung function, clearing mucus, and enhancing immune defenses; Stimulates liver enzyme activity, aiding in toxin breakdown and fat metabolism; High in polyphenols and tannins, promoting skin regeneration and reducing microbial infections

Turmeric Leaf Extract is a leaf ingredient known for rich in curcuminoids and flavonoids, turmeric leaf extract reduces oxidative stress, supports cel...

#2

Guava Fiber

Strong
Fiber

Guava fiber is derived from the pulp and skin of guava fruit (Psidium guajava), offering a natural and nutrient-dense source of dietary fiber. Known for its digestive and health-promoting properties, guava fiber is increasingly used in functional foods, supplements, and wellness products. It supports gut health, blood sugar regulation, and cardiovascular health while providing antioxidants and essential nutrients.

Guava Fiber is a fruit ingredient known for guava fiber is derived from the pulp and skin of guava fruit (psidium guajava), offering a natural and nut...

#3

Lion's Mane Mushroom

Strong
Mushroom/Fungi

Cognitive Enhancement & Neuroprotection: Stimulates Nerve Growth Factor (NGF) synthesis, supporting memory, focus, mental clarity, and neurogenesis. Immune Resilience & Anti-Inflammatory Support: Beta-glucans and phenolic compounds modulate immune function and reduce systemic inflammation. Digestive Health & Gut Integrity: Supports microbiome balance and intestinal lining health. Stress Adaptation & Mood Regulation: Adaptogenic properties enhance resilience against stress and promote emotional balance. Cardiovascular Wellness: Regulates blood lipid profiles, improves circulation, and reduces arterial inflammation.

Lion's Mane Mushroom is a mushroom ingredient known for cognitive enhancement & neuroprotection: stimulates nerve growth factor (ngf) synthesis, suppo...

#4

Uruguayan Mate Leaf

Strong
Leaf/Green

Supports digestive health by promoting bile flow, easing bloating, and stimulating gastric motility.

Uruguayan Mate Leaf is a leaf ingredient known for provides a natural energy boost through caffeine and theobromine, enhancing alertness without the c...

#5

Quinine Berry

Strong
Berry

Supports immune function, reduces fever, purifies the blood, calms inflammation, aids gut defense, improves circulation, and protects cellular integrity Research further indicates that Quinine Berry may support metabolic efficiency and cellular energy production through its micronutrient and cofactor content. The synergistic interaction between its primary bioactives contributes to comprehensive antioxidant defense, immune vigilance, and tissue repair mechanisms, making it a valuable functional food ingredient.

Quinine Berry is a berry ingredient known for supports immune function, reduces fever, purifies the blood, calms inflammation, aids gut defense, impro...

#6
Turmeric Root Extract

Turmeric Root Extract

Strong
Root/Rhizome

Provides powerful anti-inflammatory and joint health support through curcumin’s inhibition of NF-κB and COX-2 pathways, reducing pain and stiffness associated with arthritis and autoimmune conditions; delivers potent antioxidant and cellular protection by neutralizing free radicals and boosting glutathione levels, guarding against oxidative stress and premature aging; enhances cognitive function and neuroprotection by elevating BDNF (brain-derived neurotrophic factor), supporting memory, focus, and neuroplasticity while mitigating neurodegenerative risks; improves digestive and gut health by stimulating bile production, promoting microbiota balance, and reducing gastrointestinal inflammation; supports cardiovascular health by improving endothelial function, reducing LDL oxidation, and enhancing circulation; strengthens immune resilience by modulating cytokine responses and supporting gut-associated lymphoid tissue activity.

Turmeric Root Extract is a root ingredient known for provides powerful anti-inflammatory and joint health support through curcumin’s inhibition of nf-...

#7

Spinach Fiber

Strong
Fiber

Enhances digestive health by promoting bowel regularity, alleviating constipation, and supporting microbial diversity in the gut.

Spinach Fiber is a fiber ingredient known for enhances digestive health by promoting bowel regularity, alleviating constipation, and supporting microb...

#8

Yacón Syrup

Strong
Extract

Blood Sugar Regulation & Metabolic Health: Contains fructooligosaccharides (FOS) that support insulin sensitivity, lower postprandial glucose levels, and aid in weight management; Prebiotic & Gut Microbiome Support: FOS and inulin promote the growth of beneficial gut bacteria, enhancing digestion and immune function; Liver Detoxification & Fat Metabolism: Stimulates bile production and enhances lipid metabolism, reducing fatty liver risk; Antioxidant & Anti-Inflammatory Properties: Rich in polyphenols and flavonoids that reduce oxidative stress and inflammation, protecting cellular health; Cardiovascular Support: Helps regulate cholesterol levels, improve circulation, and reduce arterial stiffness

Yacón Syrup is a root ingredient known for blood sugar regulation & metabolic health: contains fructooligosaccharides (fos) that support insulin sensi...

#9

Spinach Fiber

Strong
Fiber

Enhances digestive health by promoting bowel regularity, alleviating constipation, and supporting microbial diversity in the gut.

Spinach Fiber is a fiber ingredient known for enhances digestive health by promoting bowel regularity, alleviating constipation, and supporting microb...

#10

Phellinus Linteus Extract

Strong
Mushroom/Fungi

Notes (from original entry): Synergy: pair with healthy fats (to support absorption of fat-soluble phytonutrients), vitamin C–rich fruits (antioxidant network support), and fermented foods (microbiome potentiation) for a balanced whole-food stack.

Phellinus Linteus Extract is a extract ingredient known for immune modulation: activates immune pathways and increases cytokine production. Anti-Cance...

#11

Lentinula Edodes (Shiitake)

Strong
Mushroom/Fungi

Immune Support: Contains beta-glucans and lentinan, which enhance immune function and resilience against infections. Cardiovascular Health: Reduces cholesterol levels and supports heart health with compounds like eritadenine. Antioxidant Protection: Rich in selenium, vitamin D, and polyphenols, which combat oxidative stress and promote cellular health. Anti-Inflammatory Effects: Polysaccharides and other bioactive compounds reduce systemic inflammation, benefiting joint and cardiovascular health. Skin Health: Contains vitamin D and antioxidants that improve skin elasticity and protect against environmental damage. Digestive Health: High fiber content promotes gut microbiome balance and regularity.

Lentinula Edodes (Shiitake) is a mushroom ingredient known for immune support: contains beta-glucans and lentinan, which enhance immune function and r...

#12

Seaweed (Hijiki)

Strong
Vegetable

Supports digestive regularity with its rich dietary fiber.

Seaweed (Hijiki) is a vegetable ingredient known for promotes bone health due to its high calcium content. Supports digestive regularity with its rich...

#13

Chinese Jujube Fruit

Strong
Fruit

Digestive Health: Contains dietary fiber, which supports gut motility, nourishes gut microbiota, and alleviates constipation.

Chinese Jujube Fruit is a fruit ingredient known for immune support: high in vitamin c, flavonoids, and saponins, which strengthen immune defenses and...

#14

Cardamom Pod Tea

Strong
Tea

Provides dietary fiber that promotes digestive regularity and supports a healthy gut microbiome.

Cardamom Pod Tea is a tea & infusion ingredient known for cardamom pod tea, classified as a elettaria cardamomum, delivers specific wellness advantage...

#15
Basil

Basil

Strong
Herb

Digestive Health: Bioactive compounds like linalool soothe the digestive system, alleviate bloating, and support gut motility.

Basil is a herb ingredient known for antioxidant support: rich in polyphenols, flavonoids, and vitamins a and c, which combat oxidative stress and pro...

#16

Rosehip Seed

Strong
Seed

Skin Regeneration and Anti-Aging: Promotes hydration, elasticity, and cell regeneration; reduces appearance of scars, wrinkles, and hyperpigmentation. Joint and Inflammatory Support: Reduces inflammation and improves mobility through omega fatty acids and antioxidants. Cardiovascular Health: Supports cholesterol balance and circulation via polyunsaturated fatty acids and phytosterols. Immune Resilience: Enhances immune defenses through antioxidant-rich compounds like tocopherols and carotenoids. Digestive and Gut Health: Supports gut lining integrity and may aid in fat metabolism. Cognitive and Neuroprotection: Supports brain health and reduces cognitive decline risks via omega-3 fatty acids and antioxidants.

Rosehip Seed is a seed ingredient known for skin regeneration and anti-aging: promotes hydration, elasticity, and cell regeneration; reduces appearanc...

#17

Barberry Flower Extract (Berberis vulgaris)

Strong
Extract

Berberine: A potent compound with immune-boosting and gut health benefits.

Barberry Flower Extract (Berberis vulgaris) is a extract ingredient known for alkaloids: known for their antimicrobial and anti-inflammatory effects, ...

#18

Brazilian Passionfruit (Passiflora edulis)

Strong
Fruit

Rich in antioxidants, supports digestive health, boosts immune function, promotes skin health, and provides anti-inflammatory benefits.

Brazilian Passionfruit (Passiflora edulis) is a fruit ingredient known for rich in antioxidants, supports digestive health, boosts immune function, pr...

#19

Cacao Fruit

Strong
Fruit

Cacao fruit supports immune health through its high vitamin C content, boosting white blood cell production and enhancing resistance to infections. The pulp’s rich antioxidant profile, including polyphenols and flavonoids, combats oxidative stress, reduces inflammation, and protects against chronic diseases. Cacao fruit aids in cardiovascular health by promoting healthy blood circulation, regulating blood pressure, and lowering cholesterol levels due to its potassium and magnesium content. The natural sugars and B vitamins in the fruit provide sustained energy, supporting metabolism and reducing fatigue. Cacao fruit also promotes digestive health through its dietary fiber, which supports bowel regularity and gut microbiome balance. Its iron content contributes to red blood cell formation, enhancing oxygen transport and energy levels. The presence of theobromine—a natural stimulant—improves mood and cognitive function, enhancing mental clarity, memory, and focus. Additionally, cacao fruit supports skin health by promoting collagen synthesis and protecting against oxidative damage, leading to improved elasticity and radiance.

Cacao Fruit is a fruit ingredient known for cacao fruit supports immune health through its high vitamin c content, boosting white blood cell productio...

#20

Apple Guava (Psidium guajava)

Strong
Fruit

Rich in dietary fiber, promoting digestive health and regulating bowel movements.

Apple Guava (Psidium guajava) is a fruit ingredient known for high in vitamin c, which supports immune health and enhances collagen production. Rich i...