Evidence-Based Guide

Gut Health & Digestion

Prebiotic, probiotic, and gut-healing compounds that support microbiome diversity, intestinal barrier integrity, and digestive function.

20ingredients ranked by evidence

See the curated Gut Health & Digestion supplement stack →

#1
Wild Leek Stalks

Wild Leek Stalks

Strong
Vegetable

Promotes digestive health through dietary fiber and prebiotic compounds that enhance gut motility and support microbiome health.

Wild leek stalks (Allium scorodoprasum/Allium ampeloprasum) contain high concentrations of quercetin (303 µg/g), quercitrin (771 µg/g), and kaempferol...

#2
Amazonian Guava

Amazonian Guava

Strong
Fruit

Enhances gut microbiome balance and intestinal integrity through prebiotic fiber and tannins.

Amazonian Guava (Psidium guajava), whose Amazonian origin was definitively confirmed through genomic dispersal modeling across wild populations (Aréva...

#3
Jackfruit

Jackfruit

Strong
Fruit

Supports digestive and gut health with resistant starch and dietary fiber, promoting regularity and microbiome diversity.

Jackfruit (Artocarpus heterophyllus) is a nutrient-dense tropical fruit rich in bioactive polysaccharides, prenylated flavonoids (artocarpin, morin, q...

#4
Peanut

Peanut

Strong
Legume

Peanuts are a powerhouse of protein, aiding in muscle repair and growth by providing essential amino acids. They contain arginine, which enhances blood flow and reduces blood pressure. - Rich in healthy fats, peanuts support heart health by lowering LDL cholesterol levels, reducing the risk of heart disease. - Peanuts are high in antioxidants like resveratrol, which combat oxidative stress and may reduce cancer risk. - They provide a good source of niacin, which supports brain health and may reduce Alzheimer's risk by up to 70% according to studies. - Peanuts contain magnesium, which helps regulate blood sugar levels, reducing the risk of type 2 diabetes. - The fiber content in peanuts promotes digestive health by supporting regular bowel movements and preventing constipation. - Peanuts are a natural source of biotin, which supports skin health and may reduce the risk of dermatitis.

Peanuts contain resveratrol, arginine, and monounsaturated fats that support cardiovascular health by improving nitric oxide production and reducing L...

#5
Dandelion Greens

Dandelion Greens

Strong
Leaf/Green

Promotes digestive health through high dietary fiber and inulin, fostering a balanced gut microbiome.

Dandelion greens (Taraxacum officinale) contain phenolic acids like chlorogenic acid and caffeic acid that scavenge reactive oxygen species and inhibi...

#6
Soy Tempeh

Soy Tempeh

Strong
Fermented/Probiotic

High in protein, soy tempeh supports muscle health and repair by providing all essential amino acids. It aids in muscle recovery post-exercise. - Contains probiotics, which enhance gut health by balancing the intestinal flora, potentially reducing inflammation. - Rich in isoflavones, it may lower cholesterol levels by up to 10%, supporting heart health. - Provides manganese, crucial for bone health, aiding in the formation of bone regulatory enzymes. - Contains copper, which supports red blood cell production and boosts energy levels. - Offers dietary fiber, promoting satiety and aiding in weight management by slowing digestion. - Contains vitamin B12, essential for nerve function and DNA synthesis, supporting cognitive health.

Soy tempeh is a fermented soybean product containing probiotics and concentrated isoflavones that support digestive health and cardiovascular function...

#7
Blood Lime

Blood Lime

Strong
Fruit

Supports gut motility and promotes healthy digestion through its dietary fiber content.

Blood lime contains high concentrations of flavonoids (rutin, hesperidin) and limonoids that demonstrate potent antioxidant activity with 85-90% DPPH ...

#8
Palm Heart

Palm Heart

Strong
Vegetable

Promotes digestive health with high dietary fiber, which regulates bowel movements and supports microbiome balance.

Palm heart (heart of palm) is the nutrient-dense inner core of certain palm species, rich in phenolic compounds—including caffeic acid, ferulic acid, ...

#9
Mastic Tree Resin

Mastic Tree Resin

Strong
Resin

Supports gastrointestinal health by inhibiting Helicobacter pylori and reducing inflammation.

Mastic tree resin contains over 120 bioactive compounds including triterpenes like masticadienonic acid and oleanolic acid that suppress the NF-κB inf...

#10
Gamboge

Gamboge

Strong
Resin

Acts as a potent purgative, traditionally used for intense gastrointestinal cleansing.

Gamboge resin from Garcinia hanburyi contains gambogic acid (GA), gambogenic acid (GNA), and neogambogic acid (NGA) as primary bioactive compounds. GA...

#11
Cluster Dextrin (Highly Branched Cyclic Dextrin)

Cluster Dextrin (Highly Branched Cyclic Dextrin)

Strong
Other

Provides sustained energy release by maintaining stable blood glucose levels, preventing energy crashes during workouts. - Enhances endurance by improving glycogen storage, allowing athletes to perform longer without fatigue. - Supports muscle recovery by reducing muscle damage markers post-exercise, aiding in faster recovery. - Improves hydration by promoting better water absorption, crucial for maintaining performance. - Reduces gastrointestinal discomfort during exercise by being easily digestible, ensuring comfort during prolonged activities. - Boosts performance by increasing time to exhaustion, allowing athletes to push their limits. - Enhances fat oxidation during exercise, promoting efficient energy use and aiding in weight management.

Cluster dextrin is a highly branched cyclic dextrin carbohydrate that provides rapid gastric emptying and sustained energy release during exercise. Th...

#12
Quandong

Quandong

Strong
Seed

Enhances digestion and: gut microbiome balance due to high dietary fiber content.

Quandong seed contains phenolic acids, rutin, and chlorogenic acid that provide antioxidant and anti-inflammatory effects through free radical neutral...

#13
Kaffir Lime Flowers (Citrus hystrix)

Kaffir Lime Flowers (Citrus hystrix)

Strong
Leaf/Green

Supports digestion and relieves gastrointestinal discomfort through carminative properties.

Kaffir lime flowers (Citrus hystrix) yield a volatile oil dominated by citronellal (77–85%), limonene, and citronellol—monoterpenoids that exert anxio...

#14
Whey Protein Hydrolysate (WPH)

Whey Protein Hydrolysate (WPH)

Strong
Protein

Accelerates muscle recovery by providing pre-digested proteins. This ensures rapid absorption and delivery of amino acids to muscles. - Enhances muscle growth by stimulating protein synthesis. Its fast absorption rate is ideal for post-workout nutrition. - Reduces muscle soreness, allowing for quicker return to training. This is achieved through its anti-inflammatory properties. - Supports weight management by promoting satiety and reducing hunger. This aids in maintaining a healthy body composition. - Boosts immune health, thanks to its bioactive peptides. This is essential for athletes under intense physical stress. - Enhances strength gains, supporting improved performance in resistance training. Its high leucine content is key for muscle building. - Supports lean muscle maintenance, crucial during calorie deficits.

Whey protein hydrolysate is pre-digested whey protein containing di-peptides and tri-peptides that enhance absorption speed. It stimulates muscle prot...

#15
Tragacanth Gum

Tragacanth Gum

Strong
Root/Rhizome

Repairs gut lining: and protects mucosal membranes through its demulcent and prebiotic properties.

Tragacanth gum contains the polysaccharides tragacanthin and bassorin, which downregulate pro-inflammatory cytokines TNF-α, IL-1β, and NF-κB while pro...

#16
Chicory Root

Chicory Root

Strong
Vegetable

Promotes digestive health by nourishing beneficial gut bacteria and enhancing bowel regularity through its rich inulin content.

Chicory root (Cichorium intybus) delivers a concentrated matrix of inulin-type fructans, sesquiterpene lactones, and phenolic acids that exert prebiot...

#17
Cow Milk Colostrum

Cow Milk Colostrum

Strong
Protein

Enhances immune function with immunoglobulins, which are essential for fighting pathogens and reducing infection risk. - Supports gut health by promoting intestinal integrity, thanks to growth factors that repair gut lining. - Boosts athletic performance with its rich source of proteins and growth factors that aid in muscle recovery. - Promotes healthy aging by providing antioxidants that combat oxidative stress and cellular damage. - Aids in allergy relief by modulating immune responses, reducing allergic reactions. - Improves skin health with growth factors that support cell regeneration and repair. - Supports brain health with bioactive compounds that enhance cognitive function and memory.

Cow milk colostrum is the first milk produced by cows after giving birth, containing high concentrations of immunoglobulins (IgG, IgA, IgM) and growth...

#18
Seagrape

Seagrape

Strong
Fruit

Promotes digestive wellness via prebiotic fibers and digestive enzymes that nourish gut microbiota.

Seagrape (Caulerpa lentillifera) contains phenolic compounds and flavonoids that provide antioxidant activity through DPPH radical scavenging and α-gl...

#19
Bee Bread

Bee Bread

Strong
Other

Promotes gut health with naturally occurring probiotics and enzymes that enhance digestion and nutrient absorption.

Bee bread is a fermented apitherapeutic product created by honeybees through lactic acid fermentation of pollen, honey, and salivary enzymes in honeyc...

#20
Chinese Fermented Duck Eggs

Chinese Fermented Duck Eggs

Strong
Fermented/Probiotic

Supports digestive health through beneficial compounds introduced during the fermentation process.

Chinese fermented duck eggs undergo alkaline preservation using sodium carbonate, wood ash, and calcium oxide, creating chemical transformations rathe...