Evidence-Based Guide

Cardiovascular Health

Natural compounds that support healthy blood pressure, cholesterol levels, circulation, and overall cardiovascular function.

20ingredients ranked by evidence

See the curated Cardiovascular Health supplement stack →

#1
Soy Tempeh

Soy Tempeh

Strong
Fermented/Probiotic

High in protein, soy tempeh supports muscle health and repair by providing all essential amino acids. It aids in muscle recovery post-exercise. - Contains probiotics, which enhance gut health by balancing the intestinal flora, potentially reducing inflammation. - Rich in isoflavones, it may lower cholesterol levels by up to 10%, supporting heart health. - Provides manganese, crucial for bone health, aiding in the formation of bone regulatory enzymes. - Contains copper, which supports red blood cell production and boosts energy levels. - Offers dietary fiber, promoting satiety and aiding in weight management by slowing digestion. - Contains vitamin B12, essential for nerve function and DNA synthesis, supporting cognitive health.

Soy tempeh is a fermented soybean product containing probiotics and concentrated isoflavones that support digestive health and cardiovascular function...

#2
Resistant Starch (Type 2)

Resistant Starch (Type 2)

Strong
Fermented/Probiotic

Supports digestive health by feeding beneficial gut bacteria, increasing Bifidobacteria levels. This fosters a balanced microbiome. - Enhances insulin sensitivity, contributing to better blood sugar control. This is achieved through its resistant starch content. - Supports weight management by promoting satiety and reducing overall calorie intake. This is due to its low-calorie, high-fiber nature. - Reduces the risk of colon cancer by promoting the production of butyrate, a protective short-chain fatty acid. This supports colon health. - Enhances mineral absorption, particularly calcium, by improving gut health. This supports bone density and overall wellness. - Reduces inflammation by promoting the production of anti-inflammatory cytokines. This can lead to a decrease in chronic disease risk. - Supports cardiovascular health by lowering cholesterol levels. This is achieved through the fermentation process in the colon.

Resistant Starch Type 2 is a prebiotic fiber found in uncooked potatoes, green bananas, and high-amylose corn that resists digestion in the small inte...

#3
Quercetin Phytosome

Quercetin Phytosome

Strong
Compound

Enhances immune function by modulating cytokine production, improving response to pathogens. - Acts as a powerful antioxidant, reducing oxidative stress by 30% in studies. - Reduces inflammation by inhibiting NF-kB pathways, which can alleviate chronic inflammatory conditions. - Supports cardiovascular health by improving endothelial function, reducing heart disease risk. - Promotes cellular health by protecting DNA from oxidative damage, enhancing longevity. - Aids in allergy relief by stabilizing mast cells, reducing histamine release. - Enhances exercise performance by increasing mitochondrial biogenesis, boosting energy levels.

Quercetin phytosome is a phospholipid-bound form of the flavonoid quercetin that provides enhanced bioavailability compared to standard quercetin. It ...

#4
Dandelion Greens

Dandelion Greens

Strong
Leaf/Green

Reduces systemic inflammation via bioactive compounds, benefiting joint and cardiovascular health.

Dandelion greens (Taraxacum officinale) contain phenolic acids like chlorogenic acid and caffeic acid that scavenge reactive oxygen species and inhibi...

#5
Pleurotus ostreatus dual extract

Pleurotus ostreatus dual extract

Strong
Other

Supports cardiovascular health by reducing cholesterol levels, as shown in studies where LDL cholesterol dropped by 10%. This reduction helps prevent arterial plaque buildup. - Enhances immune response by stimulating macrophage activity, crucial for fighting infections. This boost can lead to a 20% increase in immune cell activity. - Provides antioxidant effects by neutralizing free radicals, which helps prevent cellular damage. This action supports overall longevity and vitality. - May aid in blood sugar regulation by improving insulin sensitivity, potentially lowering blood sugar levels by 15%. This can be beneficial for managing diabetes. - Promotes liver health by enhancing detoxification enzymes, which helps in the breakdown of toxins. This can lead to improved liver function and reduced risk of liver diseases. - Supports weight management by increasing metabolism, which can aid in burning calories more efficiently. This effect can contribute to a healthier body composition. - Enhances cognitive function by increasing neuroplasticity, which supports learning and memory retention. This can lead to improved mental clarity and focus.

Pleurotus ostreatus dual extract contains beta-glucans and lovastatin that work through HMG-CoA reductase inhibition to reduce cholesterol synthesis. ...

#6
Alaria Seaweed

Alaria Seaweed

Strong
Other

Enhances bone strength, cardiovascular health, and muscle performance with essential minerals like calcium, magnesium, and potassium.

Alaria esculenta contains potent phlorotannins and sulfated polysaccharides that exert antioxidant effects by scavenging free radicals and inhibiting ...

#7
Seagrape

Seagrape

Strong
Fruit

Enhances cardiovascular health by improving circulation and reducing oxidative stress.

Seagrape (Caulerpa lentillifera) contains phenolic compounds and flavonoids that provide antioxidant activity through DPPH radical scavenging and α-gl...

#8
Nagkesar

Nagkesar

Strong
Flower

Strengthens capillaries and enhances microcirculation, supporting overall cardiovascular health.

Nagkesar (Mesua ferrea) flowers are rich in bioactive xanthones and coumarins—notably mesuol and mammeisin—that exhibit potent antioxidant, immunomodu...

#9
Wild Leek Stalks

Wild Leek Stalks

Strong
Vegetable

Supports cardiovascular health via potassium and allicin, which help regulate blood pressure and improve heart function.

Wild leek stalks (Allium scorodoprasum/Allium ampeloprasum) contain high concentrations of quercetin (303 µg/g), quercitrin (771 µg/g), and kaempferol...

#10
Quandong

Quandong

Strong
Seed

Supports cardiovascular health: by regulating cholesterol and improving circulation with healthy fats.

Quandong seed contains phenolic acids, rutin, and chlorogenic acid that provide antioxidant and anti-inflammatory effects through free radical neutral...

#11
Elderberry 17% Anthocyanins

Elderberry 17% Anthocyanins

Strong
Fruit

Elderberry with 17% anthocyanins boosts immune function, reducing the severity and duration of colds and flu by up to 50%. - Rich in antioxidants, it protects cells from oxidative damage, lowering the risk of chronic diseases. - High vitamin C content enhances immune defense, aiding in faster recovery from illnesses. - Anthocyanins have anti-inflammatory properties, helping to alleviate symptoms of arthritis and other inflammatory conditions. - Elderberry supports cardiovascular health by improving blood vessel function and reducing cholesterol levels. - Its natural sugars provide a gentle energy boost without causing blood sugar spikes. - Elderberry may support skin health by reducing oxidative stress and promoting a youthful appearance.

Elderberry extract standardized to 17% anthocyanins contains high concentrations of cyanidin-3-glucoside and cyanidin-3-sambubioside that support immu...

#12
Amazonian Guava

Amazonian Guava

Strong
Fruit

Promotes heart function, blood flow, and blood pressure regulation with potassium and flavonoids.

Amazonian Guava (Psidium guajava), whose Amazonian origin was definitively confirmed through genomic dispersal modeling across wild populations (Aréva...

#13
Elephant Apple Vine

Elephant Apple Vine

Strong
Other

Promotes cardiovascular wellness by supporting healthy circulation and blood pressure.

Elephant Apple (*Dillenia indica* L.) contains betulinic acid as its primary bioactive compound, demonstrating anticancer activity against leukemia ce...

#14
Himalayan Caper

Himalayan Caper

Strong
Other

Strengthens cardiovascular health by improving circulatory resilience and lipid profiles.

Himalayan Caper (Capparis spinosa) contains high concentrations of glucosinolates including glucocapparin and n-propyl-glucosinolate at 21 µmol/g dry ...

#15
Crataegus monogyna (Hawthorn)

Crataegus monogyna (Hawthorn)

Strong
European

• Reduces systolic blood pressure by an average of 6.65 mmHg based on meta-analysis of 6 RCTs (n=428)

Crataegus monogyna contains oligomeric procyanidins and flavonoids that act as ACE inhibitors and calcium channel blockers. Clinical studies show it r...

#16
Blood Lime

Blood Lime

Strong
Fruit

Supports heart health and improves circulation via its potassium and flavonoid content.

Blood lime contains high concentrations of flavonoids (rutin, hesperidin) and limonoids that demonstrate potent antioxidant activity with 85-90% DPPH ...

#17
Palm Heart

Palm Heart

Strong
Vegetable

Supports cardiovascular health by aiding in the reduction of LDL cholesterol and blood pressure through fiber and potassium.

Palm heart (heart of palm) is the nutrient-dense inner core of certain palm species, rich in phenolic compounds—including caffeic acid, ferulic acid, ...

#18
Jackfruit

Jackfruit

Strong
Fruit

Promotes heart health with potassium and magnesium, which help regulate blood pressure and cardiovascular function.

Jackfruit (Artocarpus heterophyllus) is a nutrient-dense tropical fruit rich in bioactive polysaccharides, prenylated flavonoids (artocarpin, morin, q...

#19
Peanut

Peanut

Strong
Legume

Peanuts are a powerhouse of protein, aiding in muscle repair and growth by providing essential amino acids. They contain arginine, which enhances blood flow and reduces blood pressure. - Rich in healthy fats, peanuts support heart health by lowering LDL cholesterol levels, reducing the risk of heart disease. - Peanuts are high in antioxidants like resveratrol, which combat oxidative stress and may reduce cancer risk. - They provide a good source of niacin, which supports brain health and may reduce Alzheimer's risk by up to 70% according to studies. - Peanuts contain magnesium, which helps regulate blood sugar levels, reducing the risk of type 2 diabetes. - The fiber content in peanuts promotes digestive health by supporting regular bowel movements and preventing constipation. - Peanuts are a natural source of biotin, which supports skin health and may reduce the risk of dermatitis.

Peanuts contain resveratrol, arginine, and monounsaturated fats that support cardiovascular health by improving nitric oxide production and reducing L...

#20
Bee Pollen Granules

Bee Pollen Granules

Strong
Other

Protects cardiovascular health by lowering LDL cholesterol, improving circulation, and reinforcing vascular integrity.

Bee pollen granules contain concentrated phenolic compounds, flavonoids (quercetin, kaempferol, isorhamnetin), and carotenoids that inhibit NF-κB/MAPK...