Evidence-Based Guide

Cardiovascular Health

Natural compounds that support healthy blood pressure, cholesterol levels, circulation, and overall cardiovascular function.

20ingredients ranked by evidence
#1

Seaweed (Hijiki)

Strong
Vegetable

Enhances cardiovascular health via fucoxanthin and mineral content.

Seaweed (Hijiki) is a vegetable ingredient known for promotes bone health due to its high calcium content. Supports digestive regularity with its rich...

#2

Guava Fiber

Strong
Fiber

Guava fiber is derived from the pulp and skin of guava fruit (Psidium guajava), offering a natural and nutrient-dense source of dietary fiber. Known for its digestive and health-promoting properties, guava fiber is increasingly used in functional foods, supplements, and wellness products. It supports gut health, blood sugar regulation, and cardiovascular health while providing antioxidants and essential nutrients.

Guava Fiber is a fruit ingredient known for guava fiber is derived from the pulp and skin of guava fruit (psidium guajava), offering a natural and nut...

#3

Lentinula Edodes (Shiitake)

Strong
Mushroom/Fungi

Immune Support: Contains beta-glucans and lentinan, which enhance immune function and resilience against infections. Cardiovascular Health: Reduces cholesterol levels and supports heart health with compounds like eritadenine. Antioxidant Protection: Rich in selenium, vitamin D, and polyphenols, which combat oxidative stress and promote cellular health. Anti-Inflammatory Effects: Polysaccharides and other bioactive compounds reduce systemic inflammation, benefiting joint and cardiovascular health. Skin Health: Contains vitamin D and antioxidants that improve skin elasticity and protect against environmental damage. Digestive Health: High fiber content promotes gut microbiome balance and regularity.

Lentinula Edodes (Shiitake) is a mushroom ingredient known for immune support: contains beta-glucans and lentinan, which enhance immune function and r...

#4

Ganoderma Lucidum (Reishi)

Strong
Mushroom/Fungi

Cardiovascular Health: Supports healthy circulation, lowers blood pressure, and improves cholesterol balance.

Ganoderma Lucidum (Reishi) is a mushroom ingredient known for immune support: contains beta-glucans and polysaccharides that activate immune cells and...

#5

Quinine Berry

Strong
Berry

Supports immune function, reduces fever, purifies the blood, calms inflammation, aids gut defense, improves circulation, and protects cellular integrity Research further indicates that Quinine Berry may support metabolic efficiency and cellular energy production through its micronutrient and cofactor content. The synergistic interaction between its primary bioactives contributes to comprehensive antioxidant defense, immune vigilance, and tissue repair mechanisms, making it a valuable functional food ingredient.

Quinine Berry is a berry ingredient known for supports immune function, reduces fever, purifies the blood, calms inflammation, aids gut defense, impro...

#6
Turmeric Root Extract

Turmeric Root Extract

Strong
Root/Rhizome

Provides powerful anti-inflammatory and joint health support through curcumin’s inhibition of NF-κB and COX-2 pathways, reducing pain and stiffness associated with arthritis and autoimmune conditions; delivers potent antioxidant and cellular protection by neutralizing free radicals and boosting glutathione levels, guarding against oxidative stress and premature aging; enhances cognitive function and neuroprotection by elevating BDNF (brain-derived neurotrophic factor), supporting memory, focus, and neuroplasticity while mitigating neurodegenerative risks; improves digestive and gut health by stimulating bile production, promoting microbiota balance, and reducing gastrointestinal inflammation; supports cardiovascular health by improving endothelial function, reducing LDL oxidation, and enhancing circulation; strengthens immune resilience by modulating cytokine responses and supporting gut-associated lymphoid tissue activity.

Turmeric Root Extract is a root ingredient known for provides powerful anti-inflammatory and joint health support through curcumin’s inhibition of nf-...

#7

Lion's Mane Mushroom

Strong
Mushroom/Fungi

Cognitive Enhancement & Neuroprotection: Stimulates Nerve Growth Factor (NGF) synthesis, supporting memory, focus, mental clarity, and neurogenesis. Immune Resilience & Anti-Inflammatory Support: Beta-glucans and phenolic compounds modulate immune function and reduce systemic inflammation. Digestive Health & Gut Integrity: Supports microbiome balance and intestinal lining health. Stress Adaptation & Mood Regulation: Adaptogenic properties enhance resilience against stress and promote emotional balance. Cardiovascular Wellness: Regulates blood lipid profiles, improves circulation, and reduces arterial inflammation.

Lion's Mane Mushroom is a mushroom ingredient known for cognitive enhancement & neuroprotection: stimulates nerve growth factor (ngf) synthesis, suppo...

#8

Spinach Fiber

Strong
Fiber

Supports cardiovascular function through fiber-mediated cholesterol reduction, blood pressure regulation, and improved vascular health.

Spinach Fiber is a fiber ingredient known for enhances digestive health by promoting bowel regularity, alleviating constipation, and supporting microb...

#9
Asiatic Pennywort (Gotu Kola)

Asiatic Pennywort (Gotu Kola)

Strong
Herb

Supports cognitive function by enhancing memory and focus. Promotes skin health through wound healing and collagen production. Reduces anxiety and stress by calming the nervous system. Boosts circulation and supports cardiovascular health. Provides anti-inflammatory and antioxidant benefits, protecting against oxidative stress. Enhances liver and kidney function by aiding detoxification. Additionally, the nutritional profile of Asiatic Pennywort (Gotu Kola) includes - triterpenoids: support wound healing and collagen production. For enhanced efficacy, Asiatic Pennywort (Gotu Kola) can be combined with complementary ingredients. Hermetica Synergy Stack (Formulation Heuristic)

Asiatic Pennywort (Gotu Kola) is a herb ingredient known for supports cognitive function by enhancing memory and focus. promotes skin health through w...

#10

Cordyceps Sinensis Powder

Strong
Mushroom/Fungi

Enhances sexual health and libido by promoting circulation and hormonal balance.

Cordyceps Sinensis Powder is a powder ingredient known for increases energy and endurance by enhancing atp production and improving oxygen utilization...

#11
Basil

Basil

Strong
Herb

Cardiovascular Health: Potassium and magnesium help regulate blood pressure and improve heart health.

Basil is a herb ingredient known for antioxidant support: rich in polyphenols, flavonoids, and vitamins a and c, which combat oxidative stress and pro...

#12

Yacón Syrup

Strong
Extract

Blood Sugar Regulation & Metabolic Health: Contains fructooligosaccharides (FOS) that support insulin sensitivity, lower postprandial glucose levels, and aid in weight management; Prebiotic & Gut Microbiome Support: FOS and inulin promote the growth of beneficial gut bacteria, enhancing digestion and immune function; Liver Detoxification & Fat Metabolism: Stimulates bile production and enhances lipid metabolism, reducing fatty liver risk; Antioxidant & Anti-Inflammatory Properties: Rich in polyphenols and flavonoids that reduce oxidative stress and inflammation, protecting cellular health; Cardiovascular Support: Helps regulate cholesterol levels, improve circulation, and reduce arterial stiffness

Yacón Syrup is a root ingredient known for blood sugar regulation & metabolic health: contains fructooligosaccharides (fos) that support insulin sensi...

#13

Moringa Leaf Powder

Strong
Powder

Promotes cardiovascular health through cholesterol-lowering compounds and blood pressure support.

Moringa Leaf Powder is a powder ingredient known for exceptionally nutrient-dense, providing significant amounts of vitamins a, c, e, calcium, potassi...

#14

Pacific Kelp

Strong
Other

Supports thyroid function, boosts metabolic efficiency, enhances immune resilience, promotes detoxification, improves circulatory health, and contributes to cognitive clarity and skin vitality Research further indicates that Pacific Kelp may support metabolic efficiency and cellular energy production through its micronutrient and cofactor content. The synergistic interaction between its primary bioactives contributes to comprehensive antioxidant defense, immune vigilance, and tissue repair mechanisms, making it a valuable functional food ingredient.

Pacific Kelp is a algae & seaweed ingredient known for supports thyroid function, boosts metabolic efficiency, enhances immune resilience, promotes de...

#15
Asiatic Pennywort (Gotu Kola)

Asiatic Pennywort (Gotu Kola)

Strong
Herb

Supports cognitive function by enhancing memory and focus. Promotes skin health through wound healing and collagen production. Reduces anxiety and stress by calming the nervous system. Boosts circulation and supports cardiovascular health. Provides anti-inflammatory and antioxidant benefits, protecting against oxidative stress. Enhances liver and kidney function by aiding detoxification. Additionally, the nutritional profile of Asiatic Pennywort (Gotu Kola) includes - triterpenoids: support wound healing and collagen production. For enhanced efficacy, Asiatic Pennywort (Gotu Kola) can be combined with complementary ingredients. Hermetica Synergy Stack (Formulation Heuristic)

Asiatic Pennywort (Gotu Kola) is a herb ingredient known for supports cognitive function by enhancing memory and focus. promotes skin health through w...

#16

Reishi Mushroom (Ganoderma lucidum)

Strong
Mushroom/Fungi

Supports cardiovascular health by lowering LDL cholesterol and promoting healthy blood pressure regulation.

Reishi Mushroom (Ganoderma lucidum) is a mushroom ingredient known for enhances immune function by increasing white blood cell activity and modulating...

#17

Spinach Fiber

Strong
Fiber

Supports cardiovascular function through fiber-mediated cholesterol reduction, blood pressure regulation, and improved vascular health.

Spinach Fiber is a fiber ingredient known for enhances digestive health by promoting bowel regularity, alleviating constipation, and supporting microb...

#18

Cacao Fruit

Strong
Fruit

Cacao fruit supports immune health through its high vitamin C content, boosting white blood cell production and enhancing resistance to infections. The pulp’s rich antioxidant profile, including polyphenols and flavonoids, combats oxidative stress, reduces inflammation, and protects against chronic diseases. Cacao fruit aids in cardiovascular health by promoting healthy blood circulation, regulating blood pressure, and lowering cholesterol levels due to its potassium and magnesium content. The natural sugars and B vitamins in the fruit provide sustained energy, supporting metabolism and reducing fatigue. Cacao fruit also promotes digestive health through its dietary fiber, which supports bowel regularity and gut microbiome balance. Its iron content contributes to red blood cell formation, enhancing oxygen transport and energy levels. The presence of theobromine—a natural stimulant—improves mood and cognitive function, enhancing mental clarity, memory, and focus. Additionally, cacao fruit supports skin health by promoting collagen synthesis and protecting against oxidative damage, leading to improved elasticity and radiance.

Cacao Fruit is a fruit ingredient known for cacao fruit supports immune health through its high vitamin c content, boosting white blood cell productio...

#19

Rosehip Seed

Strong
Seed

Skin Regeneration and Anti-Aging: Promotes hydration, elasticity, and cell regeneration; reduces appearance of scars, wrinkles, and hyperpigmentation. Joint and Inflammatory Support: Reduces inflammation and improves mobility through omega fatty acids and antioxidants. Cardiovascular Health: Supports cholesterol balance and circulation via polyunsaturated fatty acids and phytosterols. Immune Resilience: Enhances immune defenses through antioxidant-rich compounds like tocopherols and carotenoids. Digestive and Gut Health: Supports gut lining integrity and may aid in fat metabolism. Cognitive and Neuroprotection: Supports brain health and reduces cognitive decline risks via omega-3 fatty acids and antioxidants.

Rosehip Seed is a seed ingredient known for skin regeneration and anti-aging: promotes hydration, elasticity, and cell regeneration; reduces appearanc...

#20

Seaweed (Nori Sheets)

Strong
Other

Cardiovascular Health: Contains omega-3 fatty acids and fiber to support heart function and lower LDL cholesterol.

Seaweed (Nori Sheets) is a algae & seaweed ingredient known for immune support: rich in antioxidants like vitamins a, c, and e that enhance immune def...