Evidence-Based Guide

Skin, Hair & Nails

Compounds that support collagen synthesis, skin elasticity, photoprotection, and dermal regeneration from the inside out.

20ingredients ranked by evidence
#1

Cardamom Pod Tea

Strong
Tea

Supports skin health through vitamin C-mediated collagen synthesis and antioxidant protection.

Cardamom Pod Tea is a tea & infusion ingredient known for cardamom pod tea, classified as a elettaria cardamomum, delivers specific wellness advantage...

#2

Black Currant Seeds

Strong
Seed

Rich in gamma-linolenic acid (GLA), supporting healthy inflammatory response, hormonal balance, and skin integrity.

Black Currant Seeds is a seed ingredient known for rich in gamma-linolenic acid (gla), supporting healthy inflammatory response, hormonal balance, and...

#3

Lipoic Acid (R-Alpha Lipoic Acid)

Strong
Other

Protects skin cells from UV-induced damage, supporting elasticity and reducing wrinkles.

Lipoic Acid (R-Alpha Lipoic Acid) is a bioactive compound ingredient known for neutralizes free radicals, preventing oxidative damage to cells and tis...

#4

Pacific Kelp

Strong
Other

Supports thyroid function, boosts metabolic efficiency, enhances immune resilience, promotes detoxification, improves circulatory health, and contributes to cognitive clarity and skin vitality Research further indicates that Pacific Kelp may support metabolic efficiency and cellular energy production through its micronutrient and cofactor content. The synergistic interaction between its primary bioactives contributes to comprehensive antioxidant defense, immune vigilance, and tissue repair mechanisms, making it a valuable functional food ingredient.

Pacific Kelp is a algae & seaweed ingredient known for supports thyroid function, boosts metabolic efficiency, enhances immune resilience, promotes de...

#5

Guava Fiber

Strong
Fiber

Guava fiber is derived from the pulp and skin of guava fruit (Psidium guajava), offering a natural and nutrient-dense source of dietary fiber. Known for its digestive and health-promoting properties, guava fiber is increasingly used in functional foods, supplements, and wellness products. It supports gut health, blood sugar regulation, and cardiovascular health while providing antioxidants and essential nutrients.

Guava Fiber is a fruit ingredient known for guava fiber is derived from the pulp and skin of guava fruit (psidium guajava), offering a natural and nut...

#6

Red Cabbage Leaf

Strong
Vegetable

Promotes gut and digestive health through its rich fiber and glucosinolate content that supports microbiome diversity, enhances digestion, and reduces bloating; delivers potent anti-inflammatory and cellular protection via anthocyanins and sulforaphane, reducing oxidative stress at the cellular level; supports cardiovascular and circulatory health through polyphenols and potassium that regulate blood pressure and improve arterial flexibility; strengthens immune function and detoxification pathways through high vitamin C and sulfur compounds that enhance liver cleansing and immune resilience; promotes skin health and combats aging by supporting collagen production and reducing oxidative damage through flavonoids and vitamin K.

Red Cabbage Leaf is a vegetable ingredient known for promotes gut and digestive health through its rich fiber and glucosinolate content that supports ...

#7

Brazilian Passionfruit (Passiflora edulis)

Strong
Fruit

Rich in antioxidants, supports digestive health, boosts immune function, promotes skin health, and provides anti-inflammatory benefits.

Brazilian Passionfruit (Passiflora edulis) is a fruit ingredient known for rich in antioxidants, supports digestive health, boosts immune function, pr...

#8

Spinach Fiber

Strong
Fiber

Promotes skin health with antioxidant protection from beta-carotene and vitamin C that boost collagen synthesis and reduce oxidative stress.

Spinach Fiber is a fiber ingredient known for enhances digestive health by promoting bowel regularity, alleviating constipation, and supporting microb...

#9

Lentinula Edodes (Shiitake)

Strong
Mushroom/Fungi

Immune Support: Contains beta-glucans and lentinan, which enhance immune function and resilience against infections. Cardiovascular Health: Reduces cholesterol levels and supports heart health with compounds like eritadenine. Antioxidant Protection: Rich in selenium, vitamin D, and polyphenols, which combat oxidative stress and promote cellular health. Anti-Inflammatory Effects: Polysaccharides and other bioactive compounds reduce systemic inflammation, benefiting joint and cardiovascular health. Skin Health: Contains vitamin D and antioxidants that improve skin elasticity and protect against environmental damage. Digestive Health: High fiber content promotes gut microbiome balance and regularity.

Lentinula Edodes (Shiitake) is a mushroom ingredient known for immune support: contains beta-glucans and lentinan, which enhance immune function and r...

#10

Chinese Jujube Fruit

Strong
Fruit

Skin Health: Antioxidants and vitamin C support collagen production, hydration, and skin elasticity.

Chinese Jujube Fruit is a fruit ingredient known for immune support: high in vitamin c, flavonoids, and saponins, which strengthen immune defenses and...

#11
Asiatic Pennywort (Gotu Kola)

Asiatic Pennywort (Gotu Kola)

Strong
Herb

Supports cognitive function by enhancing memory and focus. Promotes skin health through wound healing and collagen production. Reduces anxiety and stress by calming the nervous system. Boosts circulation and supports cardiovascular health. Provides anti-inflammatory and antioxidant benefits, protecting against oxidative stress. Enhances liver and kidney function by aiding detoxification. Additionally, the nutritional profile of Asiatic Pennywort (Gotu Kola) includes - triterpenoids: support wound healing and collagen production. For enhanced efficacy, Asiatic Pennywort (Gotu Kola) can be combined with complementary ingredients. Hermetica Synergy Stack (Formulation Heuristic)

Asiatic Pennywort (Gotu Kola) is a herb ingredient known for supports cognitive function by enhancing memory and focus. promotes skin health through w...

#12

Rosehip Seed

Strong
Seed

Skin Regeneration and Anti-Aging: Promotes hydration, elasticity, and cell regeneration; reduces appearance of scars, wrinkles, and hyperpigmentation. Joint and Inflammatory Support: Reduces inflammation and improves mobility through omega fatty acids and antioxidants. Cardiovascular Health: Supports cholesterol balance and circulation via polyunsaturated fatty acids and phytosterols. Immune Resilience: Enhances immune defenses through antioxidant-rich compounds like tocopherols and carotenoids. Digestive and Gut Health: Supports gut lining integrity and may aid in fat metabolism. Cognitive and Neuroprotection: Supports brain health and reduces cognitive decline risks via omega-3 fatty acids and antioxidants.

Rosehip Seed is a seed ingredient known for skin regeneration and anti-aging: promotes hydration, elasticity, and cell regeneration; reduces appearanc...

#13

Apple Guava (Psidium guajava)

Strong
Fruit

High in vitamin C, which supports immune health and enhances collagen production.

Apple Guava (Psidium guajava) is a fruit ingredient known for high in vitamin c, which supports immune health and enhances collagen production. Rich i...

#14

Seaweed (Nori Sheets)

Strong
Other

Skin Health: Nutrients in nori protect against environmental stress and support skin hydration.

Seaweed (Nori Sheets) is a algae & seaweed ingredient known for immune support: rich in antioxidants like vitamins a, c, and e that enhance immune def...

#15
Asiatic Pennywort (Gotu Kola)

Asiatic Pennywort (Gotu Kola)

Strong
Herb

Supports cognitive function by enhancing memory and focus. Promotes skin health through wound healing and collagen production. Reduces anxiety and stress by calming the nervous system. Boosts circulation and supports cardiovascular health. Provides anti-inflammatory and antioxidant benefits, protecting against oxidative stress. Enhances liver and kidney function by aiding detoxification. Additionally, the nutritional profile of Asiatic Pennywort (Gotu Kola) includes - triterpenoids: support wound healing and collagen production. For enhanced efficacy, Asiatic Pennywort (Gotu Kola) can be combined with complementary ingredients. Hermetica Synergy Stack (Formulation Heuristic)

Asiatic Pennywort (Gotu Kola) is a herb ingredient known for supports cognitive function by enhancing memory and focus. promotes skin health through w...

#16

Spinach Fiber

Strong
Fiber

Promotes skin health with antioxidant protection from beta-carotene and vitamin C that boost collagen synthesis and reduce oxidative stress.

Spinach Fiber is a fiber ingredient known for enhances digestive health by promoting bowel regularity, alleviating constipation, and supporting microb...

#17

Cordyceps Sinensis Powder

Strong
Mushroom/Fungi

Offers anti-aging benefits by reducing oxidative stress and supporting cellular regeneration.

Cordyceps Sinensis Powder is a powder ingredient known for increases energy and endurance by enhancing atp production and improving oxygen utilization...

#18

Cacao Fruit

Strong
Fruit

Cacao fruit supports immune health through its high vitamin C content, boosting white blood cell production and enhancing resistance to infections. The pulp’s rich antioxidant profile, including polyphenols and flavonoids, combats oxidative stress, reduces inflammation, and protects against chronic diseases. Cacao fruit aids in cardiovascular health by promoting healthy blood circulation, regulating blood pressure, and lowering cholesterol levels due to its potassium and magnesium content. The natural sugars and B vitamins in the fruit provide sustained energy, supporting metabolism and reducing fatigue. Cacao fruit also promotes digestive health through its dietary fiber, which supports bowel regularity and gut microbiome balance. Its iron content contributes to red blood cell formation, enhancing oxygen transport and energy levels. The presence of theobromine—a natural stimulant—improves mood and cognitive function, enhancing mental clarity, memory, and focus. Additionally, cacao fruit supports skin health by promoting collagen synthesis and protecting against oxidative damage, leading to improved elasticity and radiance.

Cacao Fruit is a fruit ingredient known for cacao fruit supports immune health through its high vitamin c content, boosting white blood cell productio...

#19

Turmeric Leaf Extract

Strong
Leaf/Green

Rich in curcuminoids and flavonoids, turmeric leaf extract reduces oxidative stress, supports cellular repair, and mitigates inflammation; Contains essential oils like turmerone and zingiberene that stimulate bile production, improve gut microbiota, and reduce bloating; Exhibits antimicrobial and expectorant properties, supporting lung function, clearing mucus, and enhancing immune defenses; Stimulates liver enzyme activity, aiding in toxin breakdown and fat metabolism; High in polyphenols and tannins, promoting skin regeneration and reducing microbial infections

Turmeric Leaf Extract is a leaf ingredient known for rich in curcuminoids and flavonoids, turmeric leaf extract reduces oxidative stress, supports cel...

#20

Lipoic Acid (R-Alpha Lipoic Acid)

Strong
Other

Protects skin cells from UV-induced damage, supporting elasticity and reducing wrinkles.

Lipoic Acid (R-Alpha Lipoic Acid) is a bioactive compound ingredient known for neutralizes free radicals, preventing oxidative damage to cells and tis...