Evidence-Based Guide

Skin, Hair & Nails

Compounds that support collagen synthesis, skin elasticity, photoprotection, and dermal regeneration from the inside out.

20ingredients ranked by evidence

See the curated Skin, Hair & Nails supplement stack →

#1
Wild Dill Fronds

Wild Dill Fronds

Strong
Herb

Promotes Skin Health: Antioxidants and vitamin C stimulate collagen production, protect against UV damage, and support skin elasticity.

Wild dill fronds contain 41 bioactive metabolites including pyridoxal, indole-3-lactate, and quercetin glucuronide that demonstrate antioxidant activi...

#2
Giant Hogweed Leaf

Giant Hogweed Leaf

Strong
Leaf/Green

Induces severe phototoxic dermatitis upon skin contact, causing blistering and chemical burns.

Giant hogweed leaf contains high concentrations of furanocoumarins like psoralen and bergapten that bind to DNA and cause severe phototoxic dermatitis...

#3
Kaffir Lime Flowers (Citrus hystrix)

Kaffir Lime Flowers (Citrus hystrix)

Strong
Leaf/Green

Aids skin hydration and anti-aging by stimulating collagen production and protecting against oxidative stress.

Kaffir lime flowers (Citrus hystrix) yield a volatile oil dominated by citronellal (77–85%), limonene, and citronellol—monoterpenoids that exert anxio...

#4
Oak Galls

Oak Galls

Strong
Other

Promotes skin healing and rejuvenation when applied topically, aiding in wound closure and reducing inflammation.

Oak galls contain 50-70% gallotannins and 2-4% gallic acid, which exert therapeutic effects through NF-κB inhibition, VEGF suppression, and Nrf2/HO-1 ...

#5
Pacific Giant Kelp

Pacific Giant Kelp

Strong
Other

Promotes skin health by providing vital minerals and antioxidants that support hydration and cellular repair.

Pacific Giant Kelp (Macrocystis pyrifera) contains sulfated polysaccharides including fucoidan, alginate, and laminarin that demonstrate antioxidant, ...

#6
Bamboo Shoot Vinegar

Bamboo Shoot Vinegar

Strong
Other

Enhances immune function and promotes skin health via its antioxidant Vitamin C content.

Bamboo shoot vinegar is a pyroligneous liquid derived from bamboo carbonization, containing over 200 bioactive compounds including 4-methylcatechol, a...

#7
Peanut

Peanut

Strong
Legume

Peanuts are a powerhouse of protein, aiding in muscle repair and growth by providing essential amino acids. They contain arginine, which enhances blood flow and reduces blood pressure. - Rich in healthy fats, peanuts support heart health by lowering LDL cholesterol levels, reducing the risk of heart disease. - Peanuts are high in antioxidants like resveratrol, which combat oxidative stress and may reduce cancer risk. - They provide a good source of niacin, which supports brain health and may reduce Alzheimer's risk by up to 70% according to studies. - Peanuts contain magnesium, which helps regulate blood sugar levels, reducing the risk of type 2 diabetes. - The fiber content in peanuts promotes digestive health by supporting regular bowel movements and preventing constipation. - Peanuts are a natural source of biotin, which supports skin health and may reduce the risk of dermatitis.

Peanuts contain resveratrol, arginine, and monounsaturated fats that support cardiovascular health by improving nitric oxide production and reducing L...

#8
African Black Soap Nut

African Black Soap Nut

Strong
Nut

Gently cleanses the skin with saponins that act as natural surfactants, removing dirt and oil without disrupting the skin barrier.

The term 'African Black Soap Nut' combines elements of traditional West African black soap and soap nuts (Sapindus mukorossi), which contain 6-10% tri...

#9
Makrut Lime

Makrut Lime

Strong
Fruit

Enhances skin health and elasticity by boosting collagen synthesis via its high vitamin C content.

Makrut lime (Citrus hystrix) is a Southeast Asian citrus fruit rich in bioactive compounds—including citronellal (up to 77.29%), citronellol, polymeth...

#10
Alaria Seaweed

Alaria Seaweed

Strong
Other

Improves skin and joint health via bioactive compounds that support collagen formation and cellular repair.

Alaria esculenta contains potent phlorotannins and sulfated polysaccharides that exert antioxidant effects by scavenging free radicals and inhibiting ...

#11
Elderberry 17% Anthocyanins

Elderberry 17% Anthocyanins

Strong
Fruit

Elderberry with 17% anthocyanins boosts immune function, reducing the severity and duration of colds and flu by up to 50%. - Rich in antioxidants, it protects cells from oxidative damage, lowering the risk of chronic diseases. - High vitamin C content enhances immune defense, aiding in faster recovery from illnesses. - Anthocyanins have anti-inflammatory properties, helping to alleviate symptoms of arthritis and other inflammatory conditions. - Elderberry supports cardiovascular health by improving blood vessel function and reducing cholesterol levels. - Its natural sugars provide a gentle energy boost without causing blood sugar spikes. - Elderberry may support skin health by reducing oxidative stress and promoting a youthful appearance.

Elderberry extract standardized to 17% anthocyanins contains high concentrations of cyanidin-3-glucoside and cyanidin-3-sambubioside that support immu...

#12
Seagrape

Seagrape

Strong
Fruit

Supports skin collagen synthesis and protects against oxidative stress, promoting dermal health.

Seagrape (Caulerpa lentillifera) contains phenolic compounds and flavonoids that provide antioxidant activity through DPPH radical scavenging and α-gl...

#13
Elderflower Root

Elderflower Root

Strong
Herb

Promotes skin health by supporting detoxification and cellular regeneration.

Elderflower root from Sambucus nigra contains flavonoids like rutin and quercetin, plus phenolic acids including chlorogenic acid, which inhibit infla...

#14
Cow Milk Colostrum

Cow Milk Colostrum

Strong
Protein

Enhances immune function with immunoglobulins, which are essential for fighting pathogens and reducing infection risk. - Supports gut health by promoting intestinal integrity, thanks to growth factors that repair gut lining. - Boosts athletic performance with its rich source of proteins and growth factors that aid in muscle recovery. - Promotes healthy aging by providing antioxidants that combat oxidative stress and cellular damage. - Aids in allergy relief by modulating immune responses, reducing allergic reactions. - Improves skin health with growth factors that support cell regeneration and repair. - Supports brain health with bioactive compounds that enhance cognitive function and memory.

Cow milk colostrum is the first milk produced by cows after giving birth, containing high concentrations of immunoglobulins (IgG, IgA, IgM) and growth...

#15
Blood Lime

Blood Lime

Strong
Fruit

Boosts immune function and supports collagen production due to high levels of vitamin C.

Blood lime contains high concentrations of flavonoids (rutin, hesperidin) and limonoids that demonstrate potent antioxidant activity with 85-90% DPPH ...

#16
Nagkesar

Nagkesar

Strong
Flower

Promotes skin clarity and anti-aging effects through its antioxidant and anti-inflammatory compounds.

Nagkesar (Mesua ferrea) flowers are rich in bioactive xanthones and coumarins—notably mesuol and mammeisin—that exhibit potent antioxidant, immunomodu...

#17
Tragacanth Gum

Tragacanth Gum

Strong
Root/Rhizome

Promotes wound healing: and skin recovery by forming a protective, hydrating barrier.

Tragacanth gum contains the polysaccharides tragacanthin and bassorin, which downregulate pro-inflammatory cytokines TNF-α, IL-1β, and NF-κB while pro...

#18
Quandong

Quandong

Strong
Seed

Boosts immune resilience: and skin health through its zinc and antioxidant content.

Quandong seed contains phenolic acids, rutin, and chlorogenic acid that provide antioxidant and anti-inflammatory effects through free radical neutral...

#19
Amazonian Guava

Amazonian Guava

Strong
Fruit

Supports skin hydration, elasticity, and collagen synthesis with carotenoids and flavonoids.

Amazonian Guava (Psidium guajava), whose Amazonian origin was definitively confirmed through genomic dispersal modeling across wild populations (Aréva...

#20
Sunflower Seeds (Helianthus annuus)

Sunflower Seeds (Helianthus annuus)

Strong
Other

Supports skin hydration, elasticity, and repair with high Vitamin E and linoleic acid content.

Sunflower seeds (Helianthus annuus) contain phytosterols, tocopherols, and phenolic compounds that inhibit angiotensin-converting enzyme (ACE) and pro...