Evidence-Based Guide

Antioxidant Protection

The strongest natural antioxidants ranked by ORAC value and clinical evidence — from astaxanthin to glutathione precursors.

20ingredients ranked by evidence

See the curated Antioxidant Protection supplement stack →

#1
Peanut

Peanut

Strong
Legume

Peanuts are a powerhouse of protein, aiding in muscle repair and growth by providing essential amino acids. They contain arginine, which enhances blood flow and reduces blood pressure. - Rich in healthy fats, peanuts support heart health by lowering LDL cholesterol levels, reducing the risk of heart disease. - Peanuts are high in antioxidants like resveratrol, which combat oxidative stress and may reduce cancer risk. - They provide a good source of niacin, which supports brain health and may reduce Alzheimer's risk by up to 70% according to studies. - Peanuts contain magnesium, which helps regulate blood sugar levels, reducing the risk of type 2 diabetes. - The fiber content in peanuts promotes digestive health by supporting regular bowel movements and preventing constipation. - Peanuts are a natural source of biotin, which supports skin health and may reduce the risk of dermatitis.

Peanuts contain resveratrol, arginine, and monounsaturated fats that support cardiovascular health by improving nitric oxide production and reducing L...

#2
Amazonian Guava

Amazonian Guava

Strong
Fruit

Strengthens the immune system by neutralizing free radicals with vitamin C and polyphenols.

Amazonian Guava (Psidium guajava), whose Amazonian origin was definitively confirmed through genomic dispersal modeling across wild populations (Aréva...

#3
Jackfruit

Jackfruit

Strong
Fruit

Regulates metabolic and blood sugar levels through flavonoids and polysaccharides that enhance insulin sensitivity.

Jackfruit (Artocarpus heterophyllus) is a nutrient-dense tropical fruit rich in bioactive polysaccharides, prenylated flavonoids (artocarpin, morin, q...

#4
Bee Bread

Bee Bread

Strong
Other

Offers significant antioxidant protection, shielding cells from oxidative stress with polyphenols.

Bee bread is a fermented apitherapeutic product created by honeybees through lactic acid fermentation of pollen, honey, and salivary enzymes in honeyc...

#5
African Black Soap Nut

African Black Soap Nut

Strong
Nut

Provides antioxidant protection through flavonoids and polyphenols, shielding the skin from oxidative stress and environmental pollutants.

The term 'African Black Soap Nut' combines elements of traditional West African black soap and soap nuts (Sapindus mukorossi), which contain 6-10% tri...

#6
Kaffir Lime Flowers (Citrus hystrix)

Kaffir Lime Flowers (Citrus hystrix)

Strong
Leaf/Green

Reduces inflammation and protects against oxidative stress with flavonoids and vitamin C.

Kaffir lime flowers (Citrus hystrix) yield a volatile oil dominated by citronellal (77–85%), limonene, and citronellol—monoterpenoids that exert anxio...

#7
Seagrape

Seagrape

Strong
Fruit

Enhances cardiovascular health by improving circulation and reducing oxidative stress.

Seagrape (Caulerpa lentillifera) contains phenolic compounds and flavonoids that provide antioxidant activity through DPPH radical scavenging and α-gl...

#8
Palm Heart

Palm Heart

Strong
Vegetable

Delivers antioxidant protection via phenolic compounds that combat oxidative stress.

Palm heart (heart of palm) is the nutrient-dense inner core of certain palm species, rich in phenolic compounds—including caffeic acid, ferulic acid, ...

#9
Nagkesar

Nagkesar

Strong
Flower

Promotes skin clarity and anti-aging effects through its antioxidant and anti-inflammatory compounds.

Nagkesar (Mesua ferrea) flowers are rich in bioactive xanthones and coumarins—notably mesuol and mammeisin—that exhibit potent antioxidant, immunomodu...

#10
Quercetin Phytosome

Quercetin Phytosome

Strong
Compound

Enhances immune function by modulating cytokine production, improving response to pathogens. - Acts as a powerful antioxidant, reducing oxidative stress by 30% in studies. - Reduces inflammation by inhibiting NF-kB pathways, which can alleviate chronic inflammatory conditions. - Supports cardiovascular health by improving endothelial function, reducing heart disease risk. - Promotes cellular health by protecting DNA from oxidative damage, enhancing longevity. - Aids in allergy relief by stabilizing mast cells, reducing histamine release. - Enhances exercise performance by increasing mitochondrial biogenesis, boosting energy levels.

Quercetin phytosome is a phospholipid-bound form of the flavonoid quercetin that provides enhanced bioavailability compared to standard quercetin. It ...

#11
Wild Leek Stalks

Wild Leek Stalks

Strong
Vegetable

Provides antioxidant support with polyphenols, flavonoids, and vitamin C that combat oxidative stress and cellular damage.

Wild leek stalks (Allium scorodoprasum/Allium ampeloprasum) contain high concentrations of quercetin (303 µg/g), quercitrin (771 µg/g), and kaempferol...

#12
Quandong

Quandong

Strong
Seed

Reduces oxidative stress: and protects cells with abundant antioxidants like flavonoids and polyphenols.

Quandong seed contains phenolic acids, rutin, and chlorogenic acid that provide antioxidant and anti-inflammatory effects through free radical neutral...

#13
Dandelion Greens

Dandelion Greens

Strong
Leaf/Green

Provides robust antioxidant support with beta-carotene, vitamin C, and polyphenols, protecting against oxidative damage.

Dandelion greens (Taraxacum officinale) contain phenolic acids like chlorogenic acid and caffeic acid that scavenge reactive oxygen species and inhibi...

#14
Elderberry 17% Anthocyanins

Elderberry 17% Anthocyanins

Strong
Fruit

Elderberry with 17% anthocyanins boosts immune function, reducing the severity and duration of colds and flu by up to 50%. - Rich in antioxidants, it protects cells from oxidative damage, lowering the risk of chronic diseases. - High vitamin C content enhances immune defense, aiding in faster recovery from illnesses. - Anthocyanins have anti-inflammatory properties, helping to alleviate symptoms of arthritis and other inflammatory conditions. - Elderberry supports cardiovascular health by improving blood vessel function and reducing cholesterol levels. - Its natural sugars provide a gentle energy boost without causing blood sugar spikes. - Elderberry may support skin health by reducing oxidative stress and promoting a youthful appearance.

Elderberry extract standardized to 17% anthocyanins contains high concentrations of cyanidin-3-glucoside and cyanidin-3-sambubioside that support immu...

#15
Chicory Root

Chicory Root

Strong
Vegetable

Reduces systemic inflammation with its array of polyphenols and sesquiterpene lactones.

Chicory root (Cichorium intybus) delivers a concentrated matrix of inulin-type fructans, sesquiterpene lactones, and phenolic acids that exert prebiot...

#16
Blood Lime

Blood Lime

Strong
Fruit

Combats oxidative stress and promotes cellular health through its rich content of vitamin C and anthocyanins.

Blood lime contains high concentrations of flavonoids (rutin, hesperidin) and limonoids that demonstrate potent antioxidant activity with 85-90% DPPH ...

#17
Monk Fruit

Monk Fruit

Strong
Fruit

Provides potent antioxidant: protection via mogrosides, flavonoids, and polyphenols, neutralizing oxidative stress.

Monk fruit (Siraitia grosvenorii) contains mogrosides—triterpene glycosides up to 300 times sweeter than sucrose—that provide zero calories and do not...

#18
Cow Milk Colostrum

Cow Milk Colostrum

Strong
Protein

Enhances immune function with immunoglobulins, which are essential for fighting pathogens and reducing infection risk. - Supports gut health by promoting intestinal integrity, thanks to growth factors that repair gut lining. - Boosts athletic performance with its rich source of proteins and growth factors that aid in muscle recovery. - Promotes healthy aging by providing antioxidants that combat oxidative stress and cellular damage. - Aids in allergy relief by modulating immune responses, reducing allergic reactions. - Improves skin health with growth factors that support cell regeneration and repair. - Supports brain health with bioactive compounds that enhance cognitive function and memory.

Cow milk colostrum is the first milk produced by cows after giving birth, containing high concentrations of immunoglobulins (IgG, IgA, IgM) and growth...

#19
Crataegus monogyna (Hawthorn)

Crataegus monogyna (Hawthorn)

Strong
European

• Shows antioxidant activity through phenolic compounds including flavonoids and proanthocyanidins (in vitro evidence)

Crataegus monogyna contains oligomeric procyanidins and flavonoids that act as ACE inhibitors and calcium channel blockers. Clinical studies show it r...

#20
Pleurotus ostreatus dual extract

Pleurotus ostreatus dual extract

Strong
Other

Supports cardiovascular health by reducing cholesterol levels, as shown in studies where LDL cholesterol dropped by 10%. This reduction helps prevent arterial plaque buildup. - Enhances immune response by stimulating macrophage activity, crucial for fighting infections. This boost can lead to a 20% increase in immune cell activity. - Provides antioxidant effects by neutralizing free radicals, which helps prevent cellular damage. This action supports overall longevity and vitality. - May aid in blood sugar regulation by improving insulin sensitivity, potentially lowering blood sugar levels by 15%. This can be beneficial for managing diabetes. - Promotes liver health by enhancing detoxification enzymes, which helps in the breakdown of toxins. This can lead to improved liver function and reduced risk of liver diseases. - Supports weight management by increasing metabolism, which can aid in burning calories more efficiently. This effect can contribute to a healthier body composition. - Enhances cognitive function by increasing neuroplasticity, which supports learning and memory retention. This can lead to improved mental clarity and focus.

Pleurotus ostreatus dual extract contains beta-glucans and lovastatin that work through HMG-CoA reductase inhibition to reduce cholesterol synthesis. ...