
Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Liu Wei Di Huang Wan is a traditional Chinese herbal formula containing six herbs including rehmannia root, which provides catalpol and other iridoid glycosides that support kidney yin function. The formula works by nourishing kidney yin energy and supporting the hypothalamic-pituitary-adrenal axis to improve vitality and hormonal balance.

Reported Benefits (Provisional)
Origin & History

Liu Wei Di Huang Wan is a traditional Chinese medicine formula composed of six herbs, including Shu Di Huang (rehmannia), Shan Zhu Yu (cornus), and Shan Yao (dioscorea). It is designed to nourish the yin and support kidney and liver health.
Research Narrative (Provisional)
Research supports Liu Wei Di Huang Wan's benefits for kidney health and Yin nourishment, with evidence from clinical trials.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
{"macronutrients": {"carbohydrates": "Approximately 60-70% of total weight", "protein": "Approximately 5-10% of total weight", "fiber": "Approximately 10-15% of total weight"}, "micronutrients": {"calcium": "10-15 mg per gram", "iron": "1-2 mg per gram", "magnesium": "5-10 mg per gram", "zinc": "0.5-1 mg per gram"}, "bioactive_compounds": {"iridoid glycosides": "5-10 mg per gram", "polysaccharides": "20-30 mg per gram", "flavonoids": "2-5 mg per gram"}, "bioavailability_notes": "The bioavailability of these compounds can vary based on individual digestion and preparation methods. Traditional preparation methods, such as decoction, may enhance the absorption of certain compounds."}
Reported Mechanism (Provisional)
The primary bioactive compounds include catalpol from rehmannia root, loganin from cornus fruit, and paeoniflorin from peony root bark, which modulate the hypothalamic-pituitary-adrenal axis and support kidney yin function. These compounds enhance antioxidant enzyme activity including superoxide dismutase and glutathione peroxidase while reducing inflammatory cytokines. The formula also supports calcium absorption and bone metabolism through improved kidney function and mineral regulation.
Clinical Narrative (Provisional)
Several randomized controlled trials with 60-120 participants have shown Liu Wei Di Huang Wan can improve kidney function markers and reduce symptoms of kidney yin deficiency over 8-12 weeks. Studies indicate 20-30% improvements in fatigue scores and bone density markers compared to placebo groups. However, most clinical research has been conducted in Asian populations with traditional Chinese medicine diagnostic criteria, limiting broader applicability. More standardized Western clinical trials are needed to establish definitive therapeutic benefits.
Also Known As
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