
Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Inonotus obliquus Sclerotium (Wild Chaga) is a parasitic fungus that forms black sclerotia on birch trees, containing bioactive betulinic acid and beta-glucans. The beta-glucans stimulate immune function through Toll-like receptor activation while betulinic acid provides anti-inflammatory effects.

Reported Benefits (Provisional)
Origin & History

Inonotus obliquus, commonly known as Wild Chaga, is a parasitic fungus found on birch trees in cold climates. It is harvested from the bark of the tree and dried for medicinal use.
Research Narrative (Provisional)
Chaga has been studied for its antioxidant and immune-boosting properties, with some in vitro and animal studies supporting its health benefits. Human trials are limited.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- High in antioxidants, particularly melanin. - Contains polysaccharides and beta-glucans. - Low in calories and fat.
Reported Mechanism (Provisional)
Beta-glucans in chaga bind to complement receptor 3 (CR3) and Toll-like receptor 2 (TLR2) on immune cells, triggering cytokine production and macrophage activation. Betulinic acid inhibits nuclear factor-kappa B (NF-κB) signaling, reducing inflammatory mediator expression. Superoxide dismutase enzymes in chaga directly neutralize reactive oxygen species through electron transfer reactions.
Clinical Narrative (Provisional)
Limited human clinical trials exist for chaga, with most evidence from animal and in vitro studies. A small 12-week study in 18 healthy adults showed 25% reduction in inflammatory markers with 600mg daily chaga extract. Animal studies demonstrate immune enhancement and liver protection, but well-designed human trials with larger sample sizes are needed. Current evidence is preliminary and requires confirmation through rigorous clinical research.
Also Known As
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