Angel Wing Mushroom — Hermetica Encyclopedia
Mushroom · Mushroom/Fungi

Angel Wing Mushroom

Provisional Strong ScoreCompound

Hermetica Superfood Encyclopedia

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Angel Wing Mushroom (*Pleurocybella porrigens*) is a highly toxic fungus directly linked to severe acute encephalopathy. Its toxicity is primarily due to pleurocybelline and other compounds that induce neurological damage and apoptosis in brain cells.

Screened PMID Records
5
Reported Benefits
Pending
Synergy Review
At a Glance
CategoryMushroom
GroupMushroom/Fungi
Public Score StatusProvisional Strong
Primary Keywordangel wing mushroom benefits
Angel Wing Mushroom — botanical
Angel Wing Mushroom — botanical close-up

Reported Benefits (Provisional)

Provides potent antioxidant protection through compounds like ergothioneine, combating oxidative stress and supporting cellular health.
Enhances immune function via polysaccharides and beta-glucans that modulate host defense mechanisms.
Exhibits anti-inflammatory properties, contributing to overall systemic wellness.
Offers neuroprotective benefits, potentially supporting brain health and cognitive function.
Supports overall vitality and well-being through its nutrient density

Origin & History

Angel Wing Mushroom — origin
Natural habitat

Angel Wing Mushroom (Pleurocybella porrigens) is a delicate, gourmet fungus native to temperate forests across Asia, Europe, and North America, where it grows on decaying conifer wood. Known for its mild flavor and high antioxidant content, it offers potential medicinal benefits, including immune support, anti-inflammatory, and neuroprotective properties.

Angel Wing Mushrooms have been cherished for centuries in traditional Asian cuisines and local remedies for their culinary versatility and health benefits. They have been used to promote vitality, boost immune resilience, and improve overall wellness across various regions.Traditional Medicine

Research Narrative (Provisional)

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

- Polysaccharides: Including beta-glucans, which boost immune function and enhance immune response. - Antioxidants: Ergothioneine, acting as a powerful antioxidant protecting against oxidative stress. - Vitamins: Vitamin B2 (Riboflavin), supporting energy metabolism and cellular repair.

Reported Mechanism (Provisional)

Mechanism of Action

The primary toxic compounds are pleurocybelline (PC), *Pleurocybella porrigens* lectin (PPL), and pleurocybellaziridine (PA). PC is lethal and forms a complex with PPL, which exhibits exo-protease activity that degrades proteins from both N- and C-termini. This complex also disrupts the blood-brain barrier, and in combination with PA, it significantly increases apoptotic cells in the mouse hippocampus, directly triggering acute encephalopathy.

Clinical Narrative (Provisional)

In 2004, a significant outbreak occurred in Japan where 59 individuals developed acute encephalopathy after consuming Angel Wing Mushrooms. Affected individuals suffered severe neurological damage, with some cases resulting in death or persistent neurological deficits. This event established a clear and direct causal link between the consumption of *Pleurocybella porrigens* and severe neurotoxicity, underscoring its dangerous nature.

Also Known As

Pleurocybella porrigensSugihiratake

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.
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