
Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Angel Wing Mushroom (*Pleurocybella porrigens*) is a highly toxic fungus directly linked to severe acute encephalopathy. Its toxicity is primarily due to pleurocybelline and other compounds that induce neurological damage and apoptosis in brain cells.

Reported Benefits (Provisional)
Origin & History

Angel Wing Mushroom (Pleurocybella porrigens) is a delicate, gourmet fungus native to temperate forests across Asia, Europe, and North America, where it grows on decaying conifer wood. Known for its mild flavor and high antioxidant content, it offers potential medicinal benefits, including immune support, anti-inflammatory, and neuroprotective properties.
Research Narrative (Provisional)
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Polysaccharides: Including beta-glucans, which boost immune function and enhance immune response. - Antioxidants: Ergothioneine, acting as a powerful antioxidant protecting against oxidative stress. - Vitamins: Vitamin B2 (Riboflavin), supporting energy metabolism and cellular repair.
Reported Mechanism (Provisional)
The primary toxic compounds are pleurocybelline (PC), *Pleurocybella porrigens* lectin (PPL), and pleurocybellaziridine (PA). PC is lethal and forms a complex with PPL, which exhibits exo-protease activity that degrades proteins from both N- and C-termini. This complex also disrupts the blood-brain barrier, and in combination with PA, it significantly increases apoptotic cells in the mouse hippocampus, directly triggering acute encephalopathy.
Clinical Narrative (Provisional)
In 2004, a significant outbreak occurred in Japan where 59 individuals developed acute encephalopathy after consuming Angel Wing Mushrooms. Affected individuals suffered severe neurological damage, with some cases resulting in death or persistent neurological deficits. This event established a clear and direct causal link between the consumption of *Pleurocybella porrigens* and severe neurotoxicity, underscoring its dangerous nature.
Also Known As
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