Probiotic & Fiber · Fermented/Probiotic

Bacillus coagulans GBI-30 6086

Provisional Strong Scoreprobiotic

Hermetica Superfood Encyclopedia

Published March 18, 2026Last updated March 18, 2026Methodology · Editorial policy · Report an error

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Bacillus coagulans GBI-30 6086 is a spore-forming probiotic strain that produces lactic acid and antimicrobial compounds to support digestive health. This soil-based probiotic survives stomach acid and colonizes the intestinal tract, promoting beneficial bacteria growth and reducing inflammatory cytokines.

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Screened PMID Records

Reported Benefits

Pending

Synergy Review

At a Glance

CategoryProbiotic & Fiber

GroupFermented/Probiotic

Public Score StatusProvisional Strong

Primary KeywordBacillus coagulans GBI-30 6086 benefits

Bacillus coagulans GBI-30 6086 — botanical close-up

Reported Benefits (Provisional)

Supports digestive health by promoting beneficial gut bacteria, enhancing nutrient absorption. - Enhances immune function through increased antibody production, reducing infection risk. - Reduces inflammation by modulating cytokine levels, promoting comfort. - Improves skin health by reducing systemic inflammation, leading to clearer skin. - Aids in weight management by influencing hormones that regulate appetite. - Boosts mood by producing neurotransmitters like serotonin, enhancing mental well-being. - Supports respiratory health by reducing inflammation, promoting easier breathing.

Origin & History

Natural habitat

Bacillus coagulans GBI-30 6086 is a soil-based probiotic strain derived from natural soil environments. It is produced through fermentation and is known for its ability to survive in harsh conditions.

“Bacillus coagulans has been used in traditional fermented foods for its digestive benefits and is a common ingredient in probiotic supplements.”Traditional Medicine

Research Narrative (Provisional)

Clinical trials have demonstrated its efficacy in supporting digestive health and reducing IBS symptoms. Studies highlight its stability and resilience.

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

- Produces lactic acid, aiding in gut health. - Contains spores that ensure survival through the digestive tract. - Supports the production of beneficial short-chain fatty acids.

Reported Mechanism (Provisional)

Mechanism of Action

Bacillus coagulans GBI-30 6086 produces lactic acid through lactate dehydrogenase, lowering intestinal pH to inhibit pathogenic bacteria growth. The strain synthesizes antimicrobial bacteriocins and modulates immune responses by reducing pro-inflammatory cytokines IL-6 and TNF-alpha while increasing immunoglobulin A production. Its spore-forming capability allows survival through gastric acid, enabling colonization in the small and large intestines.

Clinical Narrative (Provisional)

Multiple randomized controlled trials with 50-300 participants demonstrate efficacy for digestive health and immune support. Studies show 2 billion CFU daily reduces IBS symptoms by 20-40% and decreases upper respiratory infections by 27%. A 90-day trial found significant improvements in protein absorption and reduced inflammatory markers. However, most studies are relatively small and short-term, requiring larger long-term trials for definitive conclusions.

Also Known As

Bacillus coagulansGBI-306086 strainSpore-forming probioticSoil-based organismSBO probioticLactobacillus sporogenes

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.

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