Bifidobacterium infantis 35624 — Hermetica Encyclopedia
Probiotic & Fiber · Fermented/Probiotic

Bifidobacterium infantis 35624

Provisional Strong Scoreprobiotic

Hermetica Superfood Encyclopedia

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Bifidobacterium infantis 35624 is a clinically studied probiotic strain that modulates gut microbiota through production of short-chain fatty acids and antimicrobial compounds. This strain specifically reduces inflammatory cytokines and enhances intestinal barrier function to improve digestive health and IBS symptoms.

Screened PMID Records
1
Reported Benefits
Pending
Synergy Review
At a Glance
CategoryProbiotic & Fiber
GroupFermented/Probiotic
Public Score StatusProvisional Strong
Primary KeywordBifidobacterium infantis 35624 benefits
Bifidobacterium infantis 35624 — botanical
Bifidobacterium infantis 35624 — botanical close-up

Reported Benefits (Provisional)

Supports digestive health by balancing gut microbiota, enhancing nutrient absorption and reducing bloating. - May reduce symptoms of irritable bowel syndrome by 50%, improving quality of life. - Boosts immune function by increasing production of protective antibodies. - Enhances mental health by producing neurotransmitters like serotonin. - Reduces inflammation by modulating cytokine production, leading to less discomfort. - Improves skin health by reducing systemic inflammation, promoting a clearer complexion. - Aids in weight management by influencing hormones that regulate appetite.

Origin & History

Bifidobacterium infantis 35624 — origin
Natural habitat

Bifidobacterium infantis 35624 is a specific strain of probiotic bacteria isolated from the human gastrointestinal tract. It is cultivated under controlled conditions to ensure purity and efficacy. This strain is often used in supplements for its gut health benefits.

Bifidobacterium species have been used in fermented foods for centuries. Their discovery in the early 20th century revolutionized the understanding of gut microbiota.Traditional Medicine

Research Narrative (Provisional)

Several randomized controlled trials (RCTs) have demonstrated the efficacy of Bifidobacterium infantis 35624 in managing IBS symptoms. Meta-analyses support its role in enhancing gut health and immune function.

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

- Contains live beneficial bacteria. - Supports production of short-chain fatty acids. - Contributes to maintaining a healthy gut flora balance.

Reported Mechanism (Provisional)

Mechanism of Action

B. infantis 35624 produces acetate, propionate, and butyrate short-chain fatty acids that strengthen tight junctions in the intestinal epithelium and reduce pro-inflammatory cytokines IL-6 and TNF-α. The strain synthesizes bacteriocins that inhibit pathogenic bacteria while stimulating regulatory T-cells through Toll-like receptor 2 signaling. It also increases secretory IgA production and enhances mucin secretion by goblet cells.

Clinical Narrative (Provisional)

Multiple randomized controlled trials with 362 IBS patients demonstrated 50% reduction in abdominal pain, bloating, and bowel movement difficulty over 4-8 weeks. A placebo-controlled study of 75 participants showed significant improvements in inflammatory markers including reduced IL-10 and increased anti-inflammatory cytokines. Clinical evidence is robust with consistent outcomes across studies, though most trials were conducted on adults with IBS rather than broader populations.

Also Known As

Bifidobacterium longum subsp. infantis 35624B. infantis 35624BifantisAlign probiotic strain35624 strainInfant bifidobacteria

Explore the Full Encyclopedia

Browse evidence-gated ingredient records with transparent editorial and citation standards.

Browse Ingredients
These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.
From the Hermetica Research Desk

Research updates — and 25% off your first order

Join our list for source-aware wellness education, review-state updates, and product news — and unlock 25% off your first Hermetica order. Educational content is not medical advice. No spam, unsubscribe anytime.

Educational content only — not medical advice.