Evidence-Based Guide

Mood & Emotional Wellbeing

Compounds that support serotonin, dopamine, and emotional resilience — from St. John's Wort to SAMe and omega-3 fatty acids.

20ingredients ranked by evidence
#1

Fijian Kava Powder (Piper methysticum)

Strong
Powder

Additionally, it supports emotional balance and may improve social engagement by reducing social anxiety.

Fijian Kava Powder (Piper methysticum) is a powder ingredient known for fijian kava powder is renowned for its ability to promote relaxation, reduce s...

#2
Asiatic Pennywort (Gotu Kola)

Asiatic Pennywort (Gotu Kola)

Strong
Herb

Intention: Mood & Stress | Cardio & Circulation

Asiatic Pennywort (Gotu Kola) is a herb ingredient known for supports cognitive function by enhancing memory and focus. promotes skin health through w...

#3
Ashwagandha (Withania somnifera)

Ashwagandha (Withania somnifera)

Strong
Herb

Regulates cortisol levels, reducing the physiological impact of stress and promoting emotional stability.

Ashwagandha (Withania somnifera) is a herb ingredient known for regulates cortisol levels, reducing the physiological impact of stress and promoting e...

#4

Black Cohosh Root (Actaea racemosa)

Strong
Root/Rhizome

Supports hormonal balance, particularly during menopause, by alleviating symptoms such as hot flashes, night sweats, and mood swings. Promotes bone health by reducing bone loss in postmenopausal women. Reduces inflammation, aiding in the management of arthritis and joint pain. Enhances sleep quality and reduces anxiety by calming the nervous system. Provides antioxidant benefits, protecting cells from oxidative stress.

Black Cohosh Root (Actaea racemosa) is a root ingredient known for supports hormonal balance, particularly during menopause, by alleviating symptoms s...

#5
Asiatic Pennywort (Gotu Kola)

Asiatic Pennywort (Gotu Kola)

Strong
Herb

Intention: Mood & Stress | Cardio & Circulation

Asiatic Pennywort (Gotu Kola) is a herb ingredient known for supports cognitive function by enhancing memory and focus. promotes skin health through w...

#6

Lion's Mane Mushroom

Strong
Mushroom/Fungi

Cognitive Enhancement & Neuroprotection: Stimulates Nerve Growth Factor (NGF) synthesis, supporting memory, focus, mental clarity, and neurogenesis. Immune Resilience & Anti-Inflammatory Support: Beta-glucans and phenolic compounds modulate immune function and reduce systemic inflammation. Digestive Health & Gut Integrity: Supports microbiome balance and intestinal lining health. Stress Adaptation & Mood Regulation: Adaptogenic properties enhance resilience against stress and promote emotional balance. Cardiovascular Wellness: Regulates blood lipid profiles, improves circulation, and reduces arterial inflammation.

Lion's Mane Mushroom is a mushroom ingredient known for cognitive enhancement & neuroprotection: stimulates nerve growth factor (ngf) synthesis, suppo...

#7

Velvet Bean Seed

Strong
Seed

Supports brain health, mood balance, cognitive function, stress adaptation, metabolic regulation, joint mobility, reproductive health, cardiovascular wellness Research further indicates that Velvet Bean Seed may support metabolic efficiency and cellular energy production through its micronutrient and cofactor content. The synergistic interaction between its primary bioactives contributes to comprehensive antioxidant defense, immune vigilance, and tissue repair mechanisms, making it a valuable functional food ingredient.

Velvet Bean Seed is a seed ingredient known for supports brain health, mood balance, cognitive function, stress adaptation, metabolic regulation, join...

#8

Chocolate Pod

Strong
Fruit

Elevates mood due to theobromine and anandamide-like compounds.

Chocolate Pod is a fruit ingredient known for exhibits potent antioxidant activity, helping to neutralize free radicals and reduce oxidative stress. S...

#9

St. John's Wort Root

Strong
Root/Rhizome

Supports mental health by enhancing neurotransmitter balance and reducing symptoms of anxiety and depression; promotes nervous system resilience by modulating stress responses and reducing oxidative stress; strengthens immune function with antimicrobial and antiviral compounds; aids in liver detoxification by supporting enzymatic activity and bile production; provides cardiovascular benefits by improving circulation and reducing arterial inflammation. Additional benefits include joint support, hormonal balance, and cellular detoxification.

St. John's Wort Root is a root ingredient known for supports mental health by enhancing neurotransmitter balance and reducing symptoms of anxiety and ...

#10

Lion's Mane Mushroom

Strong
Mushroom/Fungi

Cognitive Enhancement & Neuroprotection: Stimulates Nerve Growth Factor (NGF) synthesis, supporting memory, focus, mental clarity, and neurogenesis. Immune Resilience & Anti-Inflammatory Support: Beta-glucans and phenolic compounds modulate immune function and reduce systemic inflammation. Digestive Health & Gut Integrity: Supports microbiome balance and intestinal lining health. Stress Adaptation & Mood Regulation: Adaptogenic properties enhance resilience against stress and promote emotional balance. Cardiovascular Wellness: Regulates blood lipid profiles, improves circulation, and reduces arterial inflammation.

Lion's Mane Mushroom is a mushroom ingredient known for cognitive enhancement & neuroprotection: stimulates nerve growth factor (ngf) synthesis, suppo...

#11

Cacao Fruit

Strong
Fruit

Cacao fruit supports immune health through its high vitamin C content, boosting white blood cell production and enhancing resistance to infections. The pulp’s rich antioxidant profile, including polyphenols and flavonoids, combats oxidative stress, reduces inflammation, and protects against chronic diseases. Cacao fruit aids in cardiovascular health by promoting healthy blood circulation, regulating blood pressure, and lowering cholesterol levels due to its potassium and magnesium content. The natural sugars and B vitamins in the fruit provide sustained energy, supporting metabolism and reducing fatigue. Cacao fruit also promotes digestive health through its dietary fiber, which supports bowel regularity and gut microbiome balance. Its iron content contributes to red blood cell formation, enhancing oxygen transport and energy levels. The presence of theobromine—a natural stimulant—improves mood and cognitive function, enhancing mental clarity, memory, and focus. Additionally, cacao fruit supports skin health by promoting collagen synthesis and protecting against oxidative damage, leading to improved elasticity and radiance.

Cacao Fruit is a fruit ingredient known for cacao fruit supports immune health through its high vitamin c content, boosting white blood cell productio...

#12
Passionflower

Passionflower

Strong
Herb

Intention: Mood & Stress | Cognition & Focus

Passionflower is a herb ingredient known for promotes relaxation by modulating gaba activity in the brain. Reduces anxiety and stress-related symptoms...

#13

French Lavender Buds

Moderate
Other

Rich in antioxidants, supports relaxation, promotes skin health, enhances mood, and provides anti-inflammatory benefits.

French Lavender Buds is a flower ingredient known for rich in antioxidants, supports relaxation, promotes skin health, enhances mood, and provides ant...

#14

Quassia Seed

Moderate
Seed

Supports digestive wellness, immune resilience, liver detoxification, metabolic balance, cognitive clarity, and emotional well-being Excellent source of essential fatty acids (omega-3 and omega-6) critical for brain health, hormone synthesis, and cellular membrane integrity. Rich in plant-based protein with a favorable amino acid composition. Contains dietary fiber, phytosterols, and lignans that support cardiovascular health and hormonal balance. Provides concentrated minerals including zinc, magnesium, and selenium.

Quassia Seed is a seed ingredient known for supports digestive wellness, immune resilience, liver detoxification, metabolic balance, cognitive clarity...

#15

Cranberry Seed

Moderate
Seed

Promotes skin health and anti-aging by enhancing collagen synthesis, hydration, and elasticity through tocotrienols and omega fatty acids; Strengthens cardiovascular health by regulating cholesterol, improving circulation, and reducing vascular inflammation; Provides antioxidant protection and cellular resilience with proanthocyanidins, flavonoids, and vitamin E; Supports urinary tract and kidney health by preventing bacterial adhesion and promoting detoxification; Regulates blood sugar levels and supports metabolic function by improving insulin sensitivity and reducing inflammation; Boosts brain function and cognitive resilience through neuroprotective compounds that enhance memory, mood, and nervous system balance

Cranberry Seed is a seed ingredient known for promotes skin health and anti-aging by enhancing collagen synthesis, hydration, and elasticity through t...

#16

Raspberry Leaf

Moderate
Leaf/Green

Reproductive Health: Tones uterine muscles, supports menstrual comfort, pregnancy preparation, and postpartum recovery. Digestive Wellness: Soothes gastrointestinal tract, alleviates inflammation, and promotes bowel regularity. Immune Support: Enhances immune resilience through high vitamin C and antioxidant content. Antioxidant and Anti-Inflammatory Protection: Reduces oxidative stress, supports cellular health, and protects cardiovascular function. Energy and Bone Health: Magnesium, calcium, and iron support energy metabolism, muscle function, and bone density. Stress Resilience: Alkaloids and minerals support nervous system balance and emotional wellness.

Raspberry Leaf is a leaf ingredient known for reproductive health: tones uterine muscles, supports menstrual comfort, pregnancy preparation, and postp...

#17

Elderberry Flower

Moderate
Flower

Immune Support & Antiviral Properties: Enhances immune defense and reduces viral replication through quercetin and phenolic acids; Respiratory Health: Acts as an expectorant, clearing mucus and soothing inflamed airways; Detoxification & Liver Support: Stimulates lymphatic drainage and liver enzyme activity, supporting natural detox pathways; Skin & Anti-Aging: High in antioxidants and flavonoids that protect against oxidative stress and promote collagen synthesis; Circulatory & Cardiovascular Health: Improves blood vessel elasticity and reduces inflammation; Stress & Mood Balance: Mild nervine properties promote relaxation and emotional well-being.

Elderberry Flower is a flower ingredient known for immune support & antiviral properties: enhances immune defense and reduces viral replication throug...

#18

Spearmint Flower

Moderate
Flower

Supports cognitive clarity, digestive wellness, hormonal balance, immune resilience, respiratory health, skin vitality, and metabolic regulation Rich in flavonoids (quercetin, kaempferol, myricetin) and anthoxanthins with antioxidant and anti-allergenic activity. Contains aromatic compounds supporting relaxation, stress relief, and mood balance. Provides pollen-derived amino acids, vitamins, and trace minerals. Natural anti-inflammatory and soothing properties support skin and respiratory health.

Spearmint Flower is a flower ingredient known for supports cognitive clarity, digestive wellness, hormonal balance, immune resilience, respiratory hea...

#19

Camu Camu

Moderate
Fruit

Immune Support and Resilience: Exceptionally high in vitamin C, enhancing immune defenses, boosting white blood cell production, and fortifying resistance against infections. Antioxidant and Cellular Longevity: Polyphenols, flavonoids, and anthocyanins neutralize oxidative stress, promote DNA repair, and enhance cellular resilience. Cognitive Function and Mood Enhancement: Serotonin-boosting compounds improve mood, reduce anxiety, and enhance cognitive clarity. Anti-Inflammatory and Joint Support: Exhibits potent anti-inflammatory properties, reducing joint discomfort, improving mobility, and promoting tissue repair. Skin Health and Collagen Production: Bioavailable vitamin C stimulates collagen synthesis, reduces pigmentation, and improves skin hydration and elasticity.

Camu Camu is a fruit ingredient known for immune support and resilience: exceptionally high in vitamin c, enhancing immune defenses, boosting white bl...

#20

Graviola

Moderate
Extract

Immune Support and Antimicrobial Defense: Acetogenins and alkaloids strengthen immune defenses, inhibit pathogen growth, and support systemic immune resilience. Antioxidant and Cellular Longevity: Polyphenols and flavonoids neutralize oxidative stress, promote DNA repair, and protect against cellular damage. Anti-Inflammatory and Pain Relief: Exhibits potent anti-inflammatory properties, alleviating joint discomfort, promoting tissue repair, and enhancing mobility. Neuroprotection and Cognitive Health: Neuroprotective compounds reduce oxidative brain stress, enhance memory retention, and support cognitive clarity. Stress Relief and Emotional Balance: Mild sedative properties promote relaxation, reduce anxiety, and support restful sleep.

Graviola is a fruit ingredient known for immune support and antimicrobial defense: acetogenins and alkaloids strengthen immune defenses, inhibit patho...