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Hermetica Superfoods Encyclopedia

Results for “ashwagandha + sertraline”

One search across 6,100 publication-gated ingredient profiles, 121,278 raw interaction source rows with a reviewed-conclusion gate, condition guides, and Hermetica formulas. Typos are fine.

Interactions & Safety

Ashwagandha + Sertraline — interaction checkInteraction Review StatusOpen the review-status page for Ashwagandha and Sertraline. No safety conclusion is shown unless the accountable human-review gate passes.Linezolid + SertralineContraindicatedFDA contraindication — linezolid label states do not use with serotonergic drugs including SSRIs unless life-threatening infection with no alternative antibiotic.Rasagiline + SertralineContraindicatedFDA contraindication on rasagiline label. At least 14 days washout required between rasagiline and SSRI (5 weeks for fluoxetine).Selegiline + SertralineContraindicatedFDA contraindication — do not use together. 14-day washout after stopping selegiline before starting SSRI (and vice versa).Sertraline + St. Johns WortContraindicated🔴 STOP — Contraindicated. Do not take St. Johns Wort with Sertraline. This combination can cause serious harm or death.Amitriptyline + SertralineMajorDANGEROUS — TCA levels increase dramatically + serotonin syndrome riskActivated Charcoal + SertralineMajorDANGEROUS — separating doses by at least 2 hours before or 4 hours after is essentialSAMe + SertralineMajorDANGEROUS — do not combine serotonergic supplements with SSRIs without medical supervision5-HTP + SertralineMajor🔴 CAUTION — Major interaction between 5-HTP and Sertraline. Avoid unless under direct medical supervision.Kratom + SertralineMajor🔴 CAUTION — Major interaction between Kratom and Sertraline. Avoid unless under direct medical supervision.Sertraline + TramadolMajorFDA labels for both drugs warn against this combination. Serotonin syndrome can be fatal. Use alternative pain medication if possible.Sertraline + TianeptineMajorTianeptine and SSRIs/SNRIs — Major Interaction (Serotonin Syndrome Risk)Sertraline + SumatriptanMajor🔴 AVOID — FDA 2006 safety communication: triptan + SSRI combinations risk serotonin syndrome. Clinical significance debated but FDA warning stands. Watch for agitation, confusion, rapid heartbeat.Nortriptyline + SertralineMajorDANGEROUS — TCA level elevation + serotonin syndrome riskCyclobenzaprine + SertralineMajorFDA-documented structural and pharmacological similarity to TCAs. Serotonin syndrome cases reported with SSRI combinations. Use alternative muscle relaxants.Dextromethorphan + SertralineMajorFDA SSRI labels list dextromethorphan as a serotonergic drug. Serotonin syndrome has been reported. Advise patients to use non-DXM cough suppressants.Ashwagandha + LevothyroxineModerate🟡 USE CAUTION — Ashwagandha and Levothyroxine may interact. Talk to your doctor before combining.Alcohol + SertralineModerate🟡 MODERATE — Alcohol worsens Sertraline side effects and depression.Ashwagandha + DiazepamModerate🟡 USE CAUTION — Ashwagandha and Diazepam may interact. Talk to your doctor before combining.Ashwagandha + LorazepamModerate🟡 USE CAUTION — Ashwagandha and Lorazepam may interact. Talk to your doctor before combining.Alprazolam + AshwagandhaModerate🟡 USE CAUTION — Ashwagandha and Alprazolam may interact. Talk to your doctor before combining.Ashwagandha + EscitalopramModerate🟡 USE CAUTION — Ashwagandha and Escitalopram may interact. Talk to your doctor before combining.

Ingredients

Winter CherryRoot/Rhizome · Public score 10/10 · see review stateProvisional ingredient profile; review state is available on the canonical page.Ashwagandha (Withania somnifera)Herb · Public score 8.5/10 · see review stateProvisional ingredient profile; review state is available on the canonical page.Withania somnifera (Ashwagandha)Ayurveda · Public score 8.5/10 · see review stateProvisional ingredient profile; review state is available on the canonical page.Asgand (Withania somnifera)Middle Eastern · Public score 8/10 · see review stateProvisional ingredient profile; review state is available on the canonical page.KSM-66 (Ashwagandha Root Extract)Adaptogen · Public score 8/10 · see review stateProvisional ingredient profile; review state is available on the canonical page.Sensoril (Ashwagandha Leaf+Root)Adaptogen · Public score 7.8/10 · see review stateProvisional ingredient profile; review state is available on the canonical page.Ashwagandha TeaRoot/Rhizome · Public score 7.5/10 · see review stateProvisional ingredient profile; review state is available on the canonical page.Shoden (Ashwagandha, 35% Withanolides)Adaptogen · Public score 7/10 · see review stateProvisional ingredient profile; review state is available on the canonical page.

Public scores are publication-routing signals with separate validation state; they are not derived proof of PubMed support. Educational reference only — not medical advice. Always consult a healthcare professional before combining supplements with medication.