Sensoril (Ashwagandha Leaf+Root)

Sensoril is a patented, standardized extract of Ashwagandha (Withania somnifera) leaf and root, standardized to contain a minimum of 8% withanolide glycoside conjugates, 32% oligosaccharides, and less than 1% alkaloids. Key bioactive compounds include withanolides (steroidal lactones such as withaferin A and withanolide D) at approximately 8-10% concentration, which are the primary pharmacologically active constituents responsible for adaptogenic effects. Oligosaccharides are present at ~32%, contributing to immune-modulating and prebiotic-like activity. Alkaloids including somniferine and somnine are present at controlled low levels (<1%) to minimize potential side effects. Sitoindosides VII and VIII (acylsteryl glucosides) are present in small but bioactive quantities and contribute to anti-stress activity. Iron content is notably present in ashwagandha root at approximately 3.3 mg per 100g dry weight of raw root, though concentrated in the extract at variable levels. Choline and GABA precursors are present in trace amounts, supporting neurological effects. The extract contains minimal macronutrients in typical supplemental doses (250–500 mg): negligible fat, carbohydrates from oligosaccharides (~0.1–0.15g per 500mg dose), and negligible protein. Bioavailability notes: withanolide glycoside conjugates in Sensoril demonstrate enhanced bioavailability compared to root-only extracts due to the inclusion of leaf material; the glycoside conjugate form improves aqueous solubility and gastrointestinal absorption. Co-administration with fats or black pepper extract (piperine) may further enhance absorption. Half-life of key withanolides is estimated at 4–6 hours in human plasma.