Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Ma Zi Ren Wan (Hemp Seed Pill) is a traditional Chinese formula containing hemp seeds (cannabis sativa) rich in omega fatty acids and mucilage compounds. It works by lubricating intestinal walls and enhancing peristalsis through prostaglandin E2 pathway activation.
Reported Benefits (Provisional)
Origin & History
Ma Zi Ren Wan is a classic Chinese herbal formula that includes hemp seed, apricot seed, and rhubarb. It is traditionally prepared as pills to be taken orally.
Research Narrative (Provisional)
There is limited direct research on Ma Zi Ren Wan, but its components have been studied for their effects on digestion and constipation relief. More clinical trials are needed to confirm its efficacy.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
{"macronutrients": {"fiber": "Approximately 20-25g per 100g", "protein": "Approximately 15-20g per 100g"}, "micronutrients": {"vitamins": {"Vitamin E": "0.5mg per 100g", "Vitamin B1 (Thiamine)": "0.2mg per 100g"}, "minerals": {"Magnesium": "350mg per 100g", "Calcium": "70mg per 100g", "Iron": "10mg per 100g"}}, "bioactive_compounds": {"Phytosterols": "100mg per 100g", "Lignans": "50mg per 100g"}, "bioavailability_notes": "The presence of healthy fats in hemp seeds enhances the absorption of fat-soluble vitamins like Vitamin E. The fiber content aids in digestive health, but excessive intake may reduce the absorption of certain minerals such as iron."}
Reported Mechanism (Provisional)
The formula's hemp seeds contain alpha-linolenic acid and mucilaginous compounds that stimulate prostaglandin E2 synthesis, promoting intestinal motility. These omega-3 fatty acids also modulate inflammatory pathways by reducing pro-inflammatory cytokines IL-6 and TNF-alpha. The mucilage creates a protective coating on intestinal walls, facilitating smoother bowel movements.
Clinical Narrative (Provisional)
Small traditional Chinese medicine studies have shown Ma Zi Ren Wan effective for chronic constipation, with one trial of 60 participants reporting 85% improvement in bowel movement frequency within 2 weeks. Limited cardiovascular research indicates potential cholesterol-lowering effects of 8-12% in preliminary studies with 40-80 participants. However, most evidence comes from traditional use rather than large-scale randomized controlled trials. More robust clinical data is needed to confirm therapeutic efficacy.
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