
Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Aloe vera contains bioactive compounds including anthraquinones and polyphenols that demonstrate antioxidant and antimicrobial properties in laboratory studies. The gel from this succulent plant has been traditionally used in Ayurveda for skin conditions and digestive support.

Origin & History

Kumari, the Sanskrit name for Aloe vera (Aloe barbadensis Miller), is a succulent perennial plant native to arid regions of North Africa, the Arabian Peninsula, and East Africa, now cultivated globally. The plant's leaf gel, rind, and waste parts are extracted using methods including ultrasound-assisted extraction with ethanol (23.2% yield), heat-assisted extraction at 80°C, and maceration with 80% ethanol.
Research Narrative (Provisional)
The available research lacks human clinical trials, RCTs, or meta-analyses with PubMed PMIDs. Current studies focus exclusively on extraction optimization, chemical profiling via GC-MS/LC-MS, and in vitro antioxidant/antimicrobial testing of extracts, with no human study designs, sample sizes, or clinical outcomes reported.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
{"macronutrients": {"carbohydrates": "0.4 g per 100 g", "protein": "0.1 g per 100 g", "fat": "0.1 g per 100 g", "fiber": "0.5 g per 100 g"}, "micronutrients": {"vitamins": {"Vitamin C": "0.5 mg per 100 g", "Vitamin E": "0.01 mg per 100 g"}, "minerals": {"Calcium": "8 mg per 100 g", "Magnesium": "2 mg per 100 g", "Potassium": "9 mg per 100 g"}}, "bioactive_compounds": {"Aloin": "10-20 mg per 100 g", "Emodin": "5-10 mg per 100 g", "Aloe-emodin": "5-10 mg per 100 g", "Polyphenols": "varies, generally low concentrations"}, "bioavailability_notes": "Nutrient absorption may vary based on preparation and individual digestive health. Aloe vera gel is primarily water, which may dilute concentrations of nutrients and compounds."}
Reported Mechanism (Provisional)
Aloe vera's antioxidant activity stems from polyphenolic compounds and anthraquinones in the rind that scavenge free radicals and inhibit oxidative stress pathways. The antimicrobial effects appear to involve disruption of bacterial cell walls and interference with microbial enzyme systems. These bioactive compounds work synergistically to provide the plant's therapeutic properties.
Clinical Narrative (Provisional)
Current evidence for aloe vera is limited to preliminary laboratory studies examining extract preparations. In vitro studies have demonstrated antioxidant capacity of rind extracts containing polyphenols and anthraquinones, though specific quantified outcomes vary by extraction method. Antimicrobial activity has been observed against various bacterial strains in laboratory testing, but human clinical trials with standardized dosing are lacking. The evidence quality remains at the preliminary stage with no robust human studies available.
Also Known As
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