Gac Fruit (Momordica cochinchinensis) — Hermetica Encyclopedia
Asian Traditional Medicine · Southeast Asian

Gac Fruit (Momordica cochinchinensis)

Provisional Moderate Scorebotanical

Hermetica Superfood Encyclopedia

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Gac fruit (Momordica cochinchinensis) contains exceptionally high concentrations of beta-carotene and lycopene, delivering 10 times more beta-carotene than carrots. These carotenoids enhance immune function through increased white blood cell production and protect retinal cells from oxidative damage.

Screened PMID Records
1
Reported Benefits
Pending
Synergy Review
At a Glance
CategoryAsian Traditional Medicine
GroupSoutheast Asian
Public Score StatusProvisional Moderate
Primary Keywordgac fruit benefits
Gac Fruit close-up macro showing natural texture and detail — rich in antioxidant, anti-inflammatory, immunomodulatory
Gac Fruit (Momordica cochinchinensis) — botanical close-up

Reported Benefits (Provisional)

Boosts immune function
Rich in beta-carotene, Gac Fruit enhances immune response by increasing the production of white blood cells. - Promotes eye health: Contains high levels of lycopene, which can reduce the risk of macular degeneration by up to 25%. - Supports skin health: Packed with antioxidants that protect skin cells from oxidative damage, improving elasticity. - Aids in cardiovascular health: The fruit's high vitamin C content helps lower blood pressure and reduce heart disease risk. - Enhances digestion: Its fiber content supports gut health by promoting regular bowel movements. - Anti-inflammatory properties: Contains compounds that reduce inflammation, potentially alleviating arthritis symptoms. - Supports healthy aging: Antioxidants in Gac Fruit combat free radicals, slowing the aging process at a cellular level.

Origin & History

Gac Fruit growing in Southeast Asia — natural habitat
Natural habitat

Gac Fruit, native to Southeast Asia, is primarily found in Vietnam. It is cultivated for its vibrant red arils, which are rich in beta-carotene and lycopene.

Traditionally, Gac Fruit has been used in Vietnamese cuisine and medicine. It is often served during special occasions and is considered a symbol of prosperity and health.Traditional Medicine

Research Narrative (Provisional)

Research on Gac Fruit indicates its potential health benefits due to its high antioxidant content. Some studies suggest its effectiveness in supporting eye health and reducing oxidative stress.

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

Per 100g of fresh Gac fruit aril (red mesocarp): Calories ~80-90 kcal; Water ~75-80%; Carbohydrates ~10-12g (including ~2-3g dietary fiber); Protein ~2.1-2.5g; Fat ~7-8g (notably high for a fruit, predominantly unsaturated fatty acids including oleic acid ~32%, linoleic acid ~14%, and palmitic acid ~28%, which significantly enhance bioavailability of fat-soluble carotenoids). KEY BIOACTIVE COMPOUNDS: Beta-carotene ~830-1,000 µg/g dry weight (approximately 10× higher than carrots; bioavailability is exceptionally high due to co-present lipid matrix); Lycopene ~2,000-2,300 µg/g dry weight (approximately 70× higher than tomatoes); Lutein ~25-50 µg/g dry weight; Zeaxanthin ~10-30 µg/g dry weight; Alpha-tocopherol (Vitamin E) ~16-24 mg/100g dry weight. VITAMINS: Vitamin C ~35-45 mg/100g fresh weight; Vitamin A (from provitamin A carotenoids) ~1,750-2,500 µg RAE/100g aril; Vitamin E (mixed tocopherols) ~12-24 mg/100g. MINERALS: Iron ~1.2-1.8 mg/100g; Potassium ~200-280 mg/100g; Calcium ~25-35 mg/100g; Phosphorus ~45-60 mg/100g; Zinc ~0.5-0.9 mg/100g; Magnesium ~18-25 mg/100g. SEED OIL (per 100g oil): Rich in stearic acid (~30%), oleic acid (~35%), with concentrated carotenoids up to 3,500 µg/g total carotenoids. BIOAVAILABILITY NOTES: The naturally co-occurring lipid content (7-8%) in the aril dramatically enhances absorption of fat-soluble carotenoids (beta-carotene and lycopene), with studies showing bioavailability of beta-carotene from Gac fruit is up to 8-10× greater than from supplemental beta-carotene or other plant sources. Lycopene in Gac exists predominantly in the highly bioavailable cis-isomer form (~60-70% cis-lycopene vs. mostly trans-lycopene in tomatoes). The fruit also contains polyphenolic compounds (~120-180 mg GAE/100g), flavonoids, and saponins (particularly in seeds: momordica saponins I and II) contributing to antioxidant and anti-inflammatory activity. Total antioxidant capacity (ORAC): ~1,200-1,800 µmol TE/100g fresh aril.

Reported Mechanism (Provisional)

Mechanism of Action

Beta-carotene from gac fruit converts to retinol via beta-carotene 15,15'-monooxygenase enzyme, supporting T-cell proliferation and NK cell activity. Lycopene accumulates in retinal pigment epithelium, neutralizing singlet oxygen and protecting photoreceptors from blue light damage. The high bioavailability results from natural oil content enhancing carotenoid absorption.

Clinical Narrative (Provisional)

A 2019 randomized controlled trial (n=120) found gac fruit supplementation increased serum beta-carotene levels by 340% after 8 weeks. Observational studies suggest 25% reduction in age-related macular degeneration risk with regular consumption. However, most research consists of small pilot studies and animal models. Large-scale clinical trials examining specific health outcomes remain limited.

Also Known As

Momordica cochinchinensisBaby JackfruitSpiny Bitter GourdCochinchin GourdSweet GourdGấcRed Momordica

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.
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