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Skin, Hair & Nails: 12 Provisional Discovery Profiles

An automated discovery list of publication-gated profiles associated with skin, hair. Ordering uses condition-match signals and public score. The list is provisional, has not completed accountable human review, and is not a treatment or purchase recommendation.

Data baseline audited: 2026-07-11 · Ranking method: provisional public score + condition-match signals · Pattern set: African Baobab Nut, Amazonian Guava, Arctic Cranberry and 9 more

The Short Answer

This automated discovery list currently places African Baobab Nut, Amazonian Guava, Arctic Cranberry first for skin, hair. Ordering uses condition-match signals, provisional public score, screened PMID depth, and recognized ingredient data. It does not identify the “best” supplements or establish efficacy, safety, or suitability; inspect each profile's review state and supported fields.

Skin, Hair & Nails ingredient profiles: provisional comparison

Use this table to compare public ranking signals, then open each profile to inspect its review state, supported fields, safety context, and screened citation mappings.

RankSupplementMatched termsPublic score stateScreened PMIDs
#1African Baobab Nutskin, collagenValidated score 10/101
#2Amazonian Guavaskin, collagen, elasticValidated score 10/101
#3Arctic Cranberryskin, collagen, elasticValidated score 10/106
#4Arctic SeaberryskinValidated score 10/101
#55-Alpha Reductaseskin, hairValidated score 9/103
#6African Black Soap Nutskin, elastic, dermaValidated score 9/101
#7Alaria Esculenta ExtractskinValidated score 9/101
#8Amazon Nut Oilskin, elastic, dermaValidated score 9/101
  1. 1
    African Baobab Nut
    Nut · 1 screened PMID mapping · matches: skin, collagen

    Validated profile summary: African Baobab Nut (Adansonia digitata) seeds are rich in polyphenolic compounds—including epicatechin, EGCG, and procyanidins—that activate AMPK/PI3K-Akt insulin-signaling pathway…

    Validated score 10/10
  2. 2
    Amazonian Guava
    Fruit · 1 screened PMID mapping · matches: skin, collagen, elastic

    Validated profile summary: Amazonian Guava (Psidium guajava), whose Amazonian origin was definitively confirmed through genomic dispersal modeling across wild populations (Arévalo-Marín et al., 2024; PMID: 3…

    Validated score 10/10
  3. 3
    Arctic Cranberry
    Fruit · 6 screened PMID mappings · matches: skin, collagen, elastic, derma

    Validated profile summary: Arctic cranberry (Vaccinium oxycoccos and related Vaccinium spp.) is exceptionally rich in A-type proanthocyanidins (PACs), anthocyanins, quercetin, and vitamin C that inhibit urop…

    Validated score 10/10
  4. 4
    Arctic Seaberry
    Berry · 1 screened PMID mapping · matches: skin

    Validated profile summary: Arctic Seaberry (Hippophae rhamnoides) contains exceptionally high concentrations of isorhamnetin, quercetin, omega-7 fatty acids, and vitamin C that modulate PI3K/AKT/mTOR and Nrf…

    Validated score 10/10
  5. 5
    5-Alpha Reductase
    Enzyme · 3 screened PMID mappings · matches: skin, hair

    Validated profile summary: 5-alpha reductase is an enzyme that converts testosterone to dihydrotestosterone (DHT), playing a crucial role in androgen metabolism. Inhibiting this enzyme helps reduce DHT level…

    Validated score 9/10
  6. 6
    African Black Soap Nut
    Nut · 1 screened PMID mapping · matches: skin, elastic, derma

    Validated profile summary: The term 'African Black Soap Nut' combines elements of traditional West African black soap and soap nuts (Sapindus mukorossi), which contain 6-10% triterpenoid saponins by mass wei…

    Validated score 9/10
  7. 7
    Alaria Esculenta Extract
    Extract · 1 screened PMID mapping · matches: skin

    Validated profile summary: Alaria esculenta extract is a North Atlantic brown macroalga rich in phlorotannins, fucoxanthin, and natural iodine that supports thyroid function and metabolic regulation. The ext…

    Validated score 9/10
  8. 8
    Amazon Nut Oil
    Oil · 1 screened PMID mapping · matches: skin, elastic, derma

    Validated profile summary: Amazon Nut Oil from Bertholletia excelsa contains exceptionally high selenium concentrations and vitamin E tocopherols that function as chain-breaking antioxidants, scavenging free…

    Validated score 9/10
  9. 9
    Astaxanthin (Haematococcus pluvialis)
    Compound · 8 screened PMID mappings · matches: skin, wrinkle, elastic

    Validated profile summary: Astaxanthin from Haematococcus pluvialis is a potent carotenoid antioxidant that crosses the blood-brain and blood-retina barriers. It reduces oxidative stress through singlet oxyg…

    Validated score 8.5/10
  10. 10
    Almond Oil
    Leaf/Green · 10 screened PMID mappings · matches: skin, collagen, hair, elastic…

    Validated profile summary: Almond oil is rich in oleic acid (62–86%), linoleic acid (6–37%), and α-tocopherol (vitamin E, 9.99–19.42 mg/100g), which collectively deliver potent anti-inflammatory, skin barrie…

    Validated score 7.5/10
  11. 11
    Astaxanthin (Beauty)
    Other · 8 screened PMID mappings · matches: skin, collagen, wrinkle, elastic…

    Validated profile summary: Astaxanthin is a powerful carotenoid antioxidant that provides superior photoprotection by neutralizing singlet oxygen and free radicals. This compound enhances skin elasticity thr…

    Validated score 7.5/10
  12. 12
    Acerola Cherry
    Fruit · 3 screened PMID mappings · matches: skin, collagen, elastic

    Validated profile summary: Acerola cherry contains exceptionally high concentrations of vitamin C (up to 4,000mg per 100g) and polyphenolic compounds that support immune function and cellular antioxidant def…

    Validated score 7/10

How this provisional order is generated

This is a transparent discovery list. Rankings are generated from the Hermetica ingredient graph, provisional public scores, screened PMID mappings, and condition-pattern matching. Rank does not prove efficacy, safety, or human review.

MethodologyReview the evidence systemEditorial teamReview the evidence systemLab-test standardsReview the evidence systemLatest researchReview the evidence system

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Frequently asked

What does this skin, hair profile list show?
It shows publication-gated profiles associated with skin, hair by automated condition-match and public-score signals: African Baobab Nut, Amazonian Guava, Arctic Cranberry, Arctic Seaberry, 5-Alpha Reductase, African Black Soap Nut, Alaria Esculenta Extract, Amazon Nut Oil, Astaxanthin (Haematococcus pluvialis), Almond Oil, Astaxanthin (Beauty), Acerola Cherry. It is a discovery index, not a clinical ranking. Review state and supported fields vary by profile.
Does the first profile have the strongest clinical evidence for skin, hair?
No. African Baobab Nut appears first by condition-match signals and provisional public score, with 1 screened PMID mappings. That order does not establish clinical efficacy, comparative superiority, or validated evidence.
How were these ingredients ranked?
Each public profile is ranked by condition-pattern matching, normalized public score, entity recognition, and presentation signals. Validation status is separate from stack order.

Other condition stacks

These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.