Mushroom · Mushroom/Fungi

Antrodia Camphorata (Niu-Chang-Chih)

Provisional Moderate Scorebotanical

Hermetica Superfood Encyclopedia

Published March 18, 2026Last updated March 18, 2026Methodology · Editorial policy · Report an error

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Antrodia Camphorata is a rare medicinal mushroom containing triterpenoids like antcin K that support liver detoxification and immune function. Its bioactive compounds enhance cytochrome P450 enzyme activity and stimulate natural killer cell production.

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Screened PMID Records

Reported Benefits

Pending

Synergy Review

At a Glance

CategoryMushroom

GroupMushroom/Fungi

Public Score StatusProvisional Moderate

Primary KeywordAntrodia Camphorata benefits

Antrodia Camphorata (Niu-Chang-Chih) — botanical close-up

Reported Benefits (Provisional)

Antrodia Camphorata supports liver health by enhancing detoxification processes, aiding in the removal of harmful toxins. - It boosts immune function by increasing the activity of natural killer cells, which are crucial for fighting infections. - This mushroom exhibits anti-cancer properties by inducing apoptosis in cancer cells, potentially reducing tumor growth. - It has anti-inflammatory effects that help reduce inflammation, which can alleviate symptoms of chronic diseases. - Antrodia Camphorata supports cardiovascular health by lowering cholesterol levels, reducing the risk of heart disease. - It enhances energy levels by improving mitochondrial function, which is essential for energy production. - This mushroom promotes skin health by reducing oxidative stress, leading to improved skin appearance and reduced signs of aging.

Origin & History

Antrodia Camphorata (Niu-Chang-Chih) — origin

Natural habitat

Antrodia Camphorata, also known as Niu-Chang-Chih, is a rare medicinal mushroom native to Taiwan. It grows on the inner heartwood of the Cinnamomum kanehirae tree and is harvested for its potent medicinal properties.

“Antrodia Camphorata has been used in traditional Taiwanese medicine for centuries, particularly for its liver-supporting properties.”Traditional Medicine

Research Narrative (Provisional)

Antrodia Camphorata has been studied in vitro and in animal models for its liver-supporting and anti-cancer properties. Human clinical trials are limited but ongoing.

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

- Rich in polysaccharides and triterpenoids. - Contains beta-glucans and polyphenols. - Low in calories and fat.

Reported Mechanism (Provisional)

Mechanism of Action

Antrodia Camphorata's triterpenoids, particularly antcin K and antcin C, activate hepatic cytochrome P450 enzymes to enhance phase I and II detoxification pathways. The polysaccharides beta-glucans stimulate macrophage activation and increase natural killer cell cytotoxicity through toll-like receptor 4 (TLR4) signaling. These compounds also modulate nuclear factor-kappa B (NF-κB) pathways to reduce inflammatory cytokine production.

Clinical Narrative (Provisional)

Human studies on Antrodia Camphorata are limited, with most evidence from animal and in vitro research. A small 12-week human trial (n=60) showed 200mg daily improved liver enzyme levels by 15-20% in participants with elevated ALT. Animal studies demonstrate significant hepatoprotective effects against toxin-induced liver damage and enhanced immune response markers. More large-scale human trials are needed to confirm therapeutic efficacy and optimal dosing protocols.

Also Known As

Antrodia cinnamomeaTaiwanofungus camphoratusNiu-Chang-ChihChang-ChihCamphor mushroomTaiwan rubyForest rubyCinnamomum mushroom

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.

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