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Detox & Liver Support: 12 Provisional Discovery Profiles

An automated discovery list of publication-gated profiles associated with detox. Ordering uses condition-match signals and public score. The list is provisional, has not completed accountable human review, and is not a treatment or purchase recommendation.

Data baseline audited: 2026-07-11 · Ranking method: provisional public score + condition-match signals · Pattern set: Ackee, Alligator Apple, Almond Mushroom and 9 more

The Short Answer

This automated discovery list currently places Ackee, Alligator Apple, Almond Mushroom first for detox. Ordering uses condition-match signals, provisional public score, screened PMID depth, and recognized ingredient data. It does not identify the “best” supplements or establish efficacy, safety, or suitability; inspect each profile's review state and supported fields.

Detox & Liver Support ingredient profiles: provisional comparison

Use this table to compare public ranking signals, then open each profile to inspect its review state, supported fields, safety context, and screened citation mappings.

RankSupplementMatched termsPublic score stateScreened PMIDs
#1Ackeeliver, detoxValidated score 10/101
#2Alligator Appledetox, hepato, glutathionValidated score 10/106
#3Almond Mushroomliver, detoxValidated score 10/1010
#4Amazonian Guaranáglutathion, phase I, phase IIValidated score 10/1010
#5Andrographisliver, detoxValidated score 10/101
#6Bael Leafliver, detox, hepatoValidated score 10/1010
#7African Black Soap Nutpurif, cleansValidated score 9/101
#8Artemisinin (Sesquiterpene Lactone)phase I, phase IIValidated score 9/105
  1. 1
    Ackee
    Fruit · 1 screened PMID mapping · matches: liver, detox

    Validated profile summary: Ackee fruit (Blighia sapida) contains bioactive phenolic compounds including catechin, epicatechin, and phloridzin that demonstrate antioxidant activity through DPPH and ABTS radic…

    Validated score 10/10
  2. 2
    Alligator Apple
    Fruit · 6 screened PMID mappings · matches: detox, hepato, glutathion, phase I…

    Validated profile summary: Alligator Apple (Annona glabra) is a tropical fruit of the Annonaceae family containing annonaceous acetogenins (notably annonacin), ent-kaurane diterpenoids, polyphenols, and flav…

    Validated score 10/10
  3. 3
    Almond Mushroom
    Mushroom/Fungi · 10 screened PMID mappings · matches: liver, detox

    Validated profile summary: Almond Mushroom (Agaricus subrufescens) is a medicinal basidiomycete rich in β-glucans, ergosterol, and polysaccharide–protein complexes that activate innate immunity by binding co…

    Validated score 10/10
  4. 4
    Amazonian Guaraná
    Seed · 10 screened PMID mappings · matches: glutathion, phase I, phase II

    Validated profile summary: Amazonian guaraná (Paullinia cupana) delivers sustained cognitive and metabolic benefits primarily through its methylxanthines—caffeine (guaranine), theobromine, and theophylline—w…

    Validated score 10/10
  5. 5
    Andrographis
    Herb · 1 screened PMID mapping · matches: liver, detox

    Validated profile summary: Andrographis paniculata inhibits inflammation through andrographolide's suppression of NF-κB transcriptional activity, reducing pro-inflammatory cytokines TNF-α and IL-6 with IC₅₀ …

    Validated score 10/10
  6. 6
    Bael Leaf
    Leaf/Green · 10 screened PMID mappings · matches: liver, detox, hepato, glutathion…

    Validated profile summary: Bael leaf (Aegle marmelos) is rich in bioactive compounds—including eugenol, marmelosin, skimmianine, tannins, flavonoids, and coumarins—that inhibit pro-inflammatory cytokines IL-…

    Validated score 10/10
  7. 7
    African Black Soap Nut
    Nut · 1 screened PMID mapping · matches: purif, cleans

    Validated profile summary: The term 'African Black Soap Nut' combines elements of traditional West African black soap and soap nuts (Sapindus mukorossi), which contain 6-10% triterpenoid saponins by mass wei…

    Validated score 9/10
  8. 8
    Artemisinin (Sesquiterpene Lactone)
    Compound · 5 screened PMID mappings · matches: phase I, phase II

    Validated profile summary: Artemisinin is a sesquiterpene lactone derived from Artemisia annua that disrupts cellular iron homeostasis and generates reactive oxygen species. It demonstrates potent antimalari…

    Validated score 9/10
  9. 9
    AHCC (Active Hexose Correlated Compound)
    Mushroom/Fungi · matches: liver, detox, toxin

    Validated profile summary: AHCC (Active Hexose Correlated Compound) is a standardized extract from shiitake mushrooms containing alpha-glucans that enhance immune function. It works by increasing natural kil…

    Validated score 8/10
  10. 10
    Alpha-Lipoic Acid (R-ALA)
    Other · 3 screened PMID mappings · matches: liver, detox, glutathion, toxin

    Validated profile summary: Alpha-lipoic acid is a unique antioxidant compound that functions in both water and fat-soluble environments throughout the body. R-ALA, the naturally occurring form, enhances insu…

    Validated score 8/10
  11. 11
    Andrographis Paniculata
    Other · 3 screened PMID mappings · matches: liver, detox, toxin

    Validated profile summary: Andrographis paniculata is a bitter herb containing andrographolide, which enhances immune function by activating macrophages and natural killer cells. The plant demonstrates poten…

    Validated score 8/10
  12. 12
    American Ginseng (Panax quinquefolius)
    Native American · 8 screened PMID mappings · matches: phase I, phase II

    Validated profile summary: American ginseng (Panax quinquefolius) contains ginsenosides that modulate glucose metabolism and cellular energy production. Clinical studies demonstrate its effectiveness in impr…

    Validated score 7.5/10

How this provisional order is generated

This is a transparent discovery list. Rankings are generated from the Hermetica ingredient graph, provisional public scores, screened PMID mappings, and condition-pattern matching. Rank does not prove efficacy, safety, or human review.

MethodologyReview the evidence systemEditorial teamReview the evidence systemLab-test standardsReview the evidence systemLatest researchReview the evidence system

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Frequently asked

What does this detox profile list show?
It shows publication-gated profiles associated with detox by automated condition-match and public-score signals: Ackee, Alligator Apple, Almond Mushroom, Amazonian Guaraná, Andrographis, Bael Leaf, African Black Soap Nut, Artemisinin (Sesquiterpene Lactone), AHCC (Active Hexose Correlated Compound), Alpha-Lipoic Acid (R-ALA), Andrographis Paniculata, American Ginseng (Panax quinquefolius). It is a discovery index, not a clinical ranking. Review state and supported fields vary by profile.
Does the first profile have the strongest clinical evidence for detox?
No. Ackee appears first by condition-match signals and provisional public score, with 1 screened PMID mappings. That order does not establish clinical efficacy, comparative superiority, or validated evidence.
How were these ingredients ranked?
Each public profile is ranked by condition-pattern matching, normalized public score, entity recognition, and presentation signals. Validation status is separate from stack order.

Other condition stacks

These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.