Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Valerian root (Valeriana officinalis) contains valerenic acid and isovaleric acid that enhance GABA neurotransmitter activity in the brain. These compounds bind to GABA-A receptors, producing sedative and anxiolytic effects that improve sleep quality and reduce anxiety.
Reported Benefits (Provisional)
Origin & History
Valerian Root, from the Valeriana Officinalis plant, is native to Europe and Asia. The roots are harvested, washed, and dried to be used in teas, capsules, and extracts.
Research Narrative (Provisional)
Numerous RCTs and meta-analyses support its efficacy in improving sleep quality and reducing anxiety. Evidence for other uses is emerging.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Contains valerenic acid, which contributes to its sedative effects. - Rich in antioxidants and essential oils. - Provides amino acids like gamma-aminobutyric acid (GABA).
Reported Mechanism (Provisional)
Valerian root's primary bioactive compounds, valerenic acid and isovaleric acid, enhance GABAergic neurotransmission by binding to GABA-A receptors and inhibiting GABA breakdown. The compounds also interact with adenosine A1 receptors and may influence serotonin and norepinephrine pathways. This multi-target approach creates sedative, anxiolytic, and muscle-relaxing effects through central nervous system depression.
Clinical Narrative (Provisional)
Multiple randomized controlled trials with sample sizes ranging from 100-400 participants demonstrate valerian root's sleep-promoting effects. Studies show 300-600mg taken 30-120 minutes before bedtime can improve sleep quality scores by 15-80% and reduce sleep latency by 15-20 minutes. However, results vary significantly between studies, with some showing minimal benefits compared to placebo. Meta-analyses suggest modest but consistent improvements in subjective sleep quality, though objective sleep parameters show less reliable changes.
Also Known As
Research updates — and 25% off your first order
Join our list for source-aware wellness education, review-state updates, and product news — and unlock 25% off your first Hermetica order. Educational content is not medical advice. No spam, unsubscribe anytime.