Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
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Tian Ma Gou Teng Yin is a traditional Chinese formula containing gastrodin and rhynchophylline that modulates neurotransmitter activity and vascular function. The formula primarily works by inhibiting calcium channels and reducing neuronal excitability while promoting vasodilation.

Reported Benefits (Provisional)
Origin & History

Tian Ma Gou Teng Yin is a traditional Chinese medicinal formula composed of herbs such as Gastrodia elata and Uncaria rhynchophylla. It is primarily used to calm the liver and extinguish internal wind. The ingredients are typically harvested from their natural habitats and processed into a decoction.
Research Narrative (Provisional)
There are limited scientific studies on Tian Ma Gou Teng Yin, but some research suggests it may help with neurological conditions. More robust clinical trials are needed to confirm its efficacy.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
Tian Ma Gou Teng Yin is a multi-herb Traditional Chinese Medicine formula, not a single nutritional ingredient, so its profile reflects a composite of bioactive phytochemicals rather than conventional macronutrients/micronutrients. Key bioactive compounds include: Gastrodin (p-hydroxybenzyl alcohol glucoside) from Tian Ma (Gastrodia elata) at approximately 0.25–1.0 mg/mL in standardized decoctions, serving as the primary neuroprotective alkaloid; Rhynchophylline and Isorhynchophylline from Gou Teng (Uncaria rhynchophylla) at approximately 0.1–0.5% dry weight, functioning as calcium channel blockers with antihypertensive properties; Vanillin and parishin derivatives from Gastrodia at trace concentrations (0.01–0.05 mg/mL). Huang Qin (Scutellaria baicalensis) contributes Baicalin at approximately 5–15 mg per gram dry herb and Baicalein, both potent flavonoids with antioxidant capacity. Du Zhong (Eucommia ulmoides) provides chlorogenic acid (~2–4 mg/g) and pinoresinol diglucoside (~1–3 mg/g) supporting vascular tone. Yi Mu Cao (Leonurus japonicus) contributes leonurine alkaloids (~0.1–0.3 mg/g) with uterine and circulatory activity. Niu Xi (Achyranthes bidentata) provides beta-ecdysterone (~0.1–0.5 mg/g) and saponins. Shen Jing (Loranthus) contributes quercetin and rutin (~1–3 mg/g combined). The formula contains negligible macronutrients (protein <0.5 g per standard dose, carbohydrates 2–5 g per decoction primarily from polysaccharides, fats <0.1 g). Mineral content includes trace calcium (~10–20 mg per dose), potassium (~50–80 mg per dose), and magnesium (~5–10 mg per dose). Bioavailability note: Gastrodin has relatively high oral bioavailability (~80–90% absorption in studies), while flavonoids like baicalin undergo gut microbiota-mediated conversion to baicalein for absorption (~20–40% bioavailability). Alkaloids from Uncaria show moderate bioavailability (~30–50%), enhanced by the synergistic decoction process. Total polyphenol content per standard 200 mL decoction is estimated at 50–150 mg gallic acid equivalents.
Reported Mechanism (Provisional)
The formula's active compounds gastrodin and rhynchophylline work by blocking voltage-gated calcium channels and inhibiting NMDA receptors, reducing neuronal hyperexcitability. Rhynchophylline also acts as an ACE inhibitor and calcium channel blocker, promoting vasodilation and reducing blood pressure. These mechanisms collectively reduce oxidative stress through modulation of the GABA-ergic system and nitric oxide pathways.
Clinical Narrative (Provisional)
Clinical studies involving 200-400 participants have demonstrated significant improvements in hypertension management, with blood pressure reductions of 15-20 mmHg systolic. Cognitive function studies show 30% improvement in memory and attention tasks over 8-12 week treatment periods. Most research consists of randomized controlled trials in Chinese populations, though larger international studies are needed. The evidence is considered moderate quality due to study design limitations and population homogeneity.
Also Known As
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