Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Silkworm Thorn Fruit (Cudrania tricuspidata) contains proteolytic serine proteases with a major 65-70 kDa enzyme that demonstrates optimal activity at pH 9.0 and 50°C. The fruit also provides phenolic compounds totaling 56.42 mg GAE/100g fresh weight, which form protein conjugates that enhance antioxidant activity through DPPH radical scavenging mechanisms.
Reported Benefits (Provisional)
Origin & History
Silkworm Thorn Fruit (Cudrania tricuspidata), also known as Che, is a deciduous tree native to East Asia, particularly China and Korea. It thrives in temperate climates and is cultivated for its edible fruit and medicinal properties. This fruit is gaining recognition in functional nutrition for its rich phytochemical profile.
Research Narrative (Provisional)
Scientific studies, including in vitro and animal models, suggest Silkworm Thorn Fruit's antioxidant, anti-inflammatory, and cardiovascular benefits. Emerging research explores its potential in metabolic regulation, immune enhancement, and neuroprotection. Further human clinical trials are needed to fully substantiate these effects.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Dietary fiber - Vitamin C - Potassium, Iron, Magnesium - Flavonoids (rutin, quercetin, catechins), Polyphenols, Plant sterols
Reported Mechanism (Provisional)
The primary serine protease (65-70 kDa) hydrolyzes proteins like soy protein isolate and whey protein concentrate, releasing bioactive amino acids including leucine and histidine. Phenolic compounds including gallic acid, ferulic acid, and syringic acid form covalent and non-covalent bonds with proteins during hydrolysis. This conjugation process enhances DPPH radical scavenging capacity up to 70% by neutralizing free radicals and breaking down β-conglycinin and glycinin protein structures.
Clinical Narrative (Provisional)
Current research is limited exclusively to in vitro enzymatic and antioxidant assays with no human or animal clinical trials reported. Laboratory studies demonstrate that ethanol-precipitated extracts at 1:4 ratios show statistically significant proteolytic activity (p < 0.05), though with lower efficiency than commercial enzymes like Alcalase or papain. Silkworm Thorn Fruit-mediated protein hydrolyzates exhibited superior antioxidant activity compared to commercial enzyme controls in DPPH scavenging and reducing power assays. The evidence base remains preliminary and requires substantial clinical validation before therapeutic applications can be established.
Also Known As
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