Hermetica Superfood Encyclopedia
The Short Answer
Setria is a patented form of reduced glutathione (L-γ-glutamyl-L-cysteinyl-glycine) that directly elevates cellular glutathione levels. It functions as the body's master antioxidant by neutralizing free radicals and supporting phase II detoxification pathways.
CategoryBranded Ingredient
GroupBranded Antioxidant
Evidence LevelModerate
Primary KeywordSetria reduced glutathione benefits
Synergy Pairings5
Health Benefits
Enhances detoxification by boosting liver function, increasing glutathione levels by 30%. This helps in the removal of toxins and supports liver health. - Strengthens the immune system by supporting white blood cell function, making the body more resilient against infections. This is vital for maintaining overall health. - Improves skin health by reducing oxidative stress, leading to a clearer, more radiant complexion. This can help reduce the appearance of blemishes and aging signs. - Supports respiratory health by reducing inflammation in the airways, which can alleviate symptoms of asthma and improve breathing. - Enhances energy levels by supporting mitochondrial function, leading to improved stamina and reduced fatigue. This is crucial for maintaining an active lifestyle. - Acts as a powerful antioxidant, protecting cells from damage and reducing the risk of chronic diseases. This promotes longevity and overall health. - Supports mental clarity by reducing oxidative stress in the brain, which can enhance focus and cognitive function.
Origin & History
Setria is a branded form of reduced glutathione, a powerful antioxidant naturally produced in the body, manufactured through a fermentation process.
“Glutathione has been recognized for its health benefits in modern medicine, though it lacks a significant historical or cultural usage context.”Traditional Medicine
Scientific Research
Research, including clinical trials, supports Setria's role in enhancing antioxidant capacity and detoxification processes in the body.
Preparation & Dosage
Typical dosage ranges from 250 to 1000 mg per day. Consult a healthcare provider before use.
Nutritional Profile
How It Works
Mechanism of Action
Setria provides bioavailable reduced glutathione that directly increases intracellular GSH concentrations. It activates glutathione peroxidase and glutathione S-transferase enzymes, facilitating conjugation of toxins for elimination. The tripeptide also regenerates vitamins C and E while maintaining the reduced state of cysteine residues in proteins.
Clinical Evidence
Human studies demonstrate that Setria supplementation increases blood glutathione levels by 30% within 6 months at 500-1000mg daily doses. A randomized controlled trial with 54 adults showed significant improvements in oxidative stress markers and immune cell function. However, most clinical evidence comes from smaller studies lasting 6 months or less, with limited long-term safety data available.
Safety & Interactions
Setria is generally well-tolerated with minimal side effects reported at standard doses up to 1000mg daily. Some individuals may experience mild gastrointestinal upset, particularly on empty stomach. It may enhance the effects of chemotherapy drugs and should be used cautiously with immunosuppressive medications. Safety during pregnancy and breastfeeding has not been established in clinical trials.
Synergy Stack
Hermetica Formulation Heuristic
Frequently Asked Questions
How much Setria glutathione should I take daily?
Clinical studies typically use 250-1000mg of Setria daily, with 500mg being the most common effective dose. Most benefits are observed at 500mg taken once daily with food for optimal absorption.
How long does it take for Setria to increase glutathione levels?
Setria can increase blood glutathione levels within 1-2 weeks of supplementation. Maximum benefits typically occur after 3-6 months of consistent daily use at therapeutic doses.
Is Setria better absorbed than regular glutathione supplements?
Yes, Setria uses a proprietary fermentation process that creates a more bioavailable form of reduced glutathione. Studies show it increases blood levels more effectively than standard glutathione supplements.
Can I take Setria with other antioxidants like vitamin C?
Setria works synergistically with vitamin C and vitamin E, helping regenerate these antioxidants after they neutralize free radicals. Taking them together may enhance overall antioxidant protection.
Does Setria help with skin health and aging?
Clinical studies show Setria may improve skin elasticity and reduce melanin production when taken at 500mg daily for 12 weeks. It supports collagen synthesis and protects against UV-induced oxidative damage.
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