Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Perilla leaf contains rosmarinic acid and alpha-linolenic acid (ALA) that provide potent antioxidant and anti-inflammatory effects. The rosmarinic acid inhibits inflammatory enzymes while ALA supports cardiovascular health through omega-3 pathways.
Reported Benefits (Provisional)
Origin & History
Native to East Asia, particularly China, Japan, and Korea; thrives in temperate climates with well-drained soils; commonly found in fields, gardens, and along roadsides. Perilla Leaf is harvested from plants found in regions spanning tropical rainforests to mountainous highlands. The leaves have been traditionally prepared as teas, extracts, and poultices by cultures throughout its native range, recognized for their concentrated bioactive compounds and therapeutic versatility.
Research Narrative (Provisional)
Studies confirm its antioxidant, anti-inflammatory, and cardioprotective properties, highlighting its bioactive compounds like rosmarinic acid and omega-3 ALA. Peer-reviewed research on Perilla Leaf includes phytochemical profiling, in vitro bioactivity screening, and nutritional composition analysis using standardized analytical methods. Published findings support its traditional applications and highlight opportunities for further clinical investigation.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Carotenoids: Includes lutein. - Vitamins: A and C. - Minerals: Calcium, iron, potassium. - Fatty acids: Alpha-linolenic acid (ALA, omega-3). - Phytochemicals: Flavonoids, rosmarinic acid, and phenolic compounds. Detailed compositional analysis of Perilla Leaf shows the presence of essential micronutrients including B-vitamins (thiamin, riboflavin, niacin), fat-soluble vitamins, and a mineral profile including potassium, phosphorus, and trace elements. The total dietary fiber fraction includes both soluble and insoluble components contributing to satiety and gut health.
Reported Mechanism (Provisional)
Rosmarinic acid in perilla leaf inhibits lipoxygenase and cyclooxygenase enzymes, reducing inflammatory mediator production. Alpha-linolenic acid converts to EPA and DHA, modulating prostaglandin synthesis and supporting cardiovascular function. Lutein accumulates in ocular tissues, filtering blue light and protecting against oxidative damage.
Clinical Narrative (Provisional)
Human studies on perilla leaf extract (200-400mg daily) show significant reductions in inflammatory markers like TNF-α and IL-6 over 8-12 weeks. Small trials (30-60 participants) demonstrate improvements in lipid profiles and antioxidant status. Most research consists of preliminary studies with limited sample sizes, requiring larger controlled trials for definitive therapeutic claims.
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