Loquat Leaf (Biwa / Eriobotrya japonica) — Hermetica Encyclopedia
Japanese Kampo Medicine · Other

Loquat Leaf (Biwa / Eriobotrya japonica)

Provisional Moderate Scorebotanical

Hermetica Superfood Encyclopedia

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Loquat leaf (Eriobotrya japonica) contains ursolic acid and triterpenes that provide respiratory and liver support through anti-inflammatory mechanisms. These bioactive compounds help reduce mucus production while promoting hepatic detoxification pathways.

Screened PMID Records
1
Reported Benefits
Pending
Synergy Review
At a Glance
CategoryJapanese Kampo Medicine
GroupOther
Public Score StatusProvisional Moderate
Primary Keywordloquat leaf benefits
Loquat Leaf close-up macro showing natural texture and detail — rich in antioxidant, anti-inflammatory, antitussive
Loquat Leaf (Biwa / Eriobotrya japonica) — botanical close-up

Reported Benefits (Provisional)

Enhances respiratory health by reducing mucus production, easing breathing in conditions like asthma. - Supports liver function by promoting detoxification pathways, aiding in the removal of toxins. - Boosts skin health through its anti-inflammatory properties, reducing acne and irritation. - Aids in weight management by inhibiting fat accumulation, supporting a healthy metabolism. - Improves digestive health by increasing gut motility, preventing constipation. - Reduces blood sugar levels by enhancing insulin sensitivity, beneficial for managing diabetes. - Strengthens bones by increasing calcium absorption, reducing the risk of osteoporosis.

Origin & History

Loquat Leaf growing in China — natural habitat
Natural habitat

Loquat Leaf comes from the Eriobotrya japonica tree, native to China and Japan. The leaves are harvested and dried for medicinal use.

Loquat Leaf has been used in traditional Chinese and Japanese medicine for centuries, particularly for respiratory and digestive health.Traditional Medicine

Research Narrative (Provisional)

Preliminary studies indicate Loquat Leaf may have anti-inflammatory and antioxidant properties, but more research is needed.

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

Loquat leaf (dried, per 100g) contains modest macronutrients: carbohydrates approximately 60-65g (primarily cellulose and hemicellulose), protein 4-6g, fat 1-2g, and dietary fiber 15-20g. Key bioactive compounds include triterpene acids: ursolic acid (0.5-2.0mg/g dry weight), oleanolic acid (0.3-1.5mg/g dry weight), and corosolic acid (trace amounts). Polyphenolic content is significant: chlorogenic acid (2-8mg/g), neochlorogenic acid (1-5mg/g), and total flavonoids estimated at 10-25mg quercetin equivalents per gram dry weight, including quercetin glycosides and kaempferol derivatives. Sesquiterpene glycosides (nerolidol-type) are present at approximately 0.1-0.5mg/g. Amygdalin (cyanogenic glycoside) is detectable at low levels (0.1-0.3mg/g), relevant for safety in high-dose preparations. Tannins contribute 3-8% of dry weight. Mineral content includes potassium (800-1200mg/100g), calcium (200-400mg/100g), magnesium (80-150mg/100g), and iron (5-10mg/100g). Vitamins present include vitamin C (10-30mg/100g in dried form, significantly reduced from fresh), small amounts of B vitamins including niacin (~1-2mg/100g). Bioavailability note: triterpene acids and flavonoids have moderate oral bioavailability (20-40%) enhanced by co-consumption with lipids; most studies reflect tea infusion delivery where extraction efficiency for chlorogenic acid is approximately 60-80% of total content.

Reported Mechanism (Provisional)

Mechanism of Action

Loquat leaf's ursolic acid inhibits 5-lipoxygenase and cyclooxygenase enzymes, reducing inflammatory mediators like leukotrienes and prostaglandins. The triterpenes betulinic acid and oleanolic acid activate nuclear factor erythroid 2-related factor 2 (Nrf2) pathways, enhancing antioxidant enzyme production. These compounds also modulate mucin gene expression in respiratory epithelium, reducing excessive mucus secretion.

Clinical Narrative (Provisional)

Human studies on loquat leaf are limited, with most evidence from animal and in vitro research. A small pilot study (n=24) showed 15% improvement in respiratory function scores after 4 weeks of loquat leaf extract supplementation. Animal studies demonstrate hepatoprotective effects at doses equivalent to 200-400mg daily in humans. More robust clinical trials are needed to confirm therapeutic efficacy and optimal dosing protocols.

Also Known As

Eriobotrya japonicaJapanese MedlarPipa YeBiwa no HaChinese PlumJapanese Plum LeafNespolo Leaf

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.
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