Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Bifidobacterium longum BB536 is a clinically studied probiotic strain that produces beneficial metabolites like acetate and lactate to support gut health. This strain specifically enhances immune function by modulating T-cell responses and strengthening the intestinal barrier.
Reported Benefits (Provisional)
Origin & History
Bifidobacterium longum BB536 is a probiotic strain isolated from human intestinal microbiota. It is produced through fermentation and is used in dietary supplements and functional foods.
Research Narrative (Provisional)
Bifidobacterium longum BB536 has been studied in multiple RCTs, showing efficacy in supporting digestive and immune health. Meta-analyses confirm its benefits in various health conditions.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Contains live probiotic cultures. - Produces acetic and lactic acids, beneficial for gut health. - Rich in bioactive compounds that support the immune system.
Reported Mechanism (Provisional)
BB536 produces short-chain fatty acids (SCFAs) including acetate and lactate that lower colonic pH and inhibit pathogenic bacteria growth. The strain enhances immune responses by stimulating dendritic cells and increasing natural killer (NK) cell activity through cytokine modulation. It strengthens intestinal barrier function by promoting tight junction proteins and reducing inflammatory mediators like TNF-α.
Clinical Narrative (Provisional)
Multiple randomized controlled trials involving over 2,000 participants have demonstrated BB536's efficacy in reducing gastrointestinal infections and supporting immune function. Studies show 30-50% reduction in respiratory infections and improved gut microbiota balance within 2-4 weeks of supplementation. Clinical research indicates effective doses range from 1-10 billion CFU daily, with benefits observed in both healthy individuals and those with compromised gut health. Evidence quality is moderate to strong for digestive and immune benefits.
Also Known As
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