Verisol (Bioactive Collagen Peptides)

Verisol is a proprietary formulation of Bioactive Collagen Peptides (BCP) derived from enzymatic hydrolysis of porcine or bovine Type I and Type III collagen. Per typical serving (2.5 g): Protein: ~2.3–2.5 g (predominantly collagen peptides with a molecular weight range of approximately 2–5 kDa, optimized for high bioavailability and intestinal absorption). Key amino acid composition per serving (approximate): Glycine ~575 mg (23%), Proline ~325 mg (13%), Hydroxyproline ~300 mg (12%), Glutamic acid ~250 mg (10%), Alanine ~225 mg (9%), Arginine ~200 mg (8%), Aspartic acid ~150 mg (6%), Lysine ~90 mg (3.6%), Serine ~75 mg (3%), Leucine ~60 mg (2.4%), with trace amounts of valine, isoleucine, threonine, phenylalanine, methionine, histidine, and tyrosine. Notably low/absent in tryptophan, making it an incomplete protein source. Fat: 0 g. Carbohydrates: 0 g. Fiber: 0 g. Calories: ~9–10 kcal per 2.5 g serving. Micronutrients: Minimal inherent vitamin or mineral content; may contain trace sodium (~15–25 mg per serving) and trace calcium and phosphorus from collagen processing. No significant levels of iron, zinc, or B-vitamins. Bioactive compounds: The key bioactivity comes from specific dipeptides and tripeptides, particularly Prolyl-Hydroxyproline (Pro-Hyp) and Hydroxyprolyl-Glycine (Hyp-Gly), which survive digestion intact and are absorbed into the bloodstream, reaching dermal fibroblasts where they stimulate endogenous collagen I, elastin, and proteoglycan biosynthesis. Bioavailability notes: The low molecular weight peptide profile (2–5 kDa) ensures >90% intestinal absorption within 1–2 hours post-ingestion. Pro-Hyp dipeptides have been detected in human blood plasma at concentrations of ~50 nmol/mL after oral ingestion of 2.5 g, confirming high oral bioavailability. The peptides act as ligands for fibroblast receptors, triggering extracellular matrix synthesis rather than serving primarily as amino acid sources. Free from cholesterol, purines, gluten, and common allergens (though not suitable for individuals with bovine/porcine protein sensitivities).