
Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Trametes versicolor extract contains bioactive polysaccharides PSK (polysaccharide-K) and PSP (polysaccharide-peptide) that stimulate immune cell activity. These compounds enhance natural killer cell function and T-cell response while supporting gut microbiome balance.

Reported Benefits (Provisional)
Origin & History

Trametes Versicolor, also known as Turkey Tail, is a common polypore mushroom found worldwide on dead logs. It is harvested for its fruiting bodies and processed into extracts like PSK and PSP.
Research Narrative (Provisional)
Trametes Versicolor has been extensively studied, with numerous RCTs and meta-analyses supporting its immune-boosting and anti-cancer effects, particularly in cancer patients.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Rich in polysaccharides, especially PSK and PSP. - Contains beta-glucans and phenolic compounds. - Low in calories and fat.
Reported Mechanism (Provisional)
PSK and PSP polysaccharides bind to toll-like receptors on immune cells, activating NF-κB and MAPK signaling pathways. This stimulates dendritic cell maturation, enhances natural killer cell cytotoxicity, and increases production of interferon-γ and interleukin-2. The compounds also modulate gut microbiota by promoting beneficial Bifidobacterium and Lactobacillus growth.
Clinical Narrative (Provisional)
Multiple randomized controlled trials involving over 8,000 cancer patients demonstrate PSK's ability to improve 5-year survival rates by 9-15% when combined with chemotherapy. Studies show 1-3g daily doses enhance immune markers including NK cell activity by 40-60% within 4-8 weeks. Gut health studies report increased beneficial bacteria populations and improved intestinal barrier function, though most trials are small-scale with 30-100 participants.
Also Known As
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