
Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Synapsa is a standardized Bacopa monnieri extract containing bacosides A and B that enhances memory formation by promoting dendritic growth and synaptic plasticity. It improves cognitive performance by modulating neurotransmitter systems including acetylcholine, GABA, and serotonin.

Reported Benefits (Provisional)
Origin & History

Synapsa is a patented form of Bacopa monnieri, an herb traditionally used in Ayurvedic medicine. It is standardized to provide consistent cognitive benefits.
Research Narrative (Provisional)
Clinical studies, including RCTs, have shown that Synapsa can improve cognitive function, particularly memory and information processing speed.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
Bacopa monnieri (Synapsa standardized extract) is a bioactive-rich botanical rather than a macronutrient source. Primary bioactive compounds include bacosides A and B (standardized to 45-55% in Synapsa extract), which are triterpenoid saponins responsible for cognitive effects. Bacoside A comprises bacoside A3, bacopasaponin C, and bacosides A1/A2. Additional saponins include bacopasaponins D, E, and F at trace concentrations. Alkaloids present include brahmine (~0.003% dry weight), herpestine, and nicotine at negligible levels (<0.001%). Flavonoids include luteolin (~0.1-0.5 mg/g dry extract) and apigenin (~0.05-0.2 mg/g). Phytosterols such as beta-sitosterol and stigmasterol are present at approximately 0.1-0.3% of dry weight. Contains betulinic acid (~0.1-0.2% dry weight) contributing antioxidant activity. Protein content is minimal (<5% dry weight), consisting primarily of structural plant proteins with low bioavailability. Carbohydrates account for approximately 40-50% of dry weight, largely as polysaccharides and glycosides. Fat content is negligible (<2% dry weight). Micronutrients include trace amounts of calcium (~50-80 mg/100g dry herb), iron (~3-5 mg/100g), and zinc (~1-2 mg/100g). Bioavailability is enhanced when taken with fats due to saponin lipophilicity; Synapsa's patented processing improves bacoside bioavailability by approximately 20-30% compared to raw extract. Typical effective dose of Synapsa extract is 300-450 mg/day standardized to bacosides.
Reported Mechanism (Provisional)
Synapsa's bacosides A and B cross the blood-brain barrier and promote protein synthesis in hippocampal neurons, increasing dendritic length and branching. The extract modulates cholinergic activity by inhibiting acetylcholinesterase while enhancing GABA and serotonin neurotransmission. These mechanisms collectively improve synaptic communication and neuroplasticity essential for memory consolidation.
Clinical Narrative (Provisional)
Multiple randomized controlled trials have demonstrated Synapsa's cognitive benefits in healthy adults. A 12-week study with 144 participants showed 24% improvement in word recall and 30% reduction in forgetfulness at 320mg daily. Additional studies report significant improvements in attention span and processing speed within 6-12 weeks. The clinical evidence is considered moderate-quality with consistent positive outcomes across diverse populations.
Also Known As
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