
Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Maoto is a traditional Japanese Kampo formula containing ephedra, cinnamon, almonds, and licorice that treats early-stage cold and flu symptoms. The primary bioactive compound ephedrine acts on beta-adrenergic receptors to bronchodilate airways and stimulate immune responses.

Reported Benefits (Provisional)
Origin & History

Maoto is a traditional Japanese Kampo formula derived from the Ephedra plant. It is prepared by decocting the stems and leaves of the Ephedra plant along with other herbs.
Research Narrative (Provisional)
Some studies, including randomized controlled trials, have shown that Maoto can be effective in reducing the duration and severity of cold symptoms. However, more research is needed to fully understand its efficacy and safety profile.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
{"macronutrients": {"protein": "0.5g per 100g", "fiber": "0.3g per 100g"}, "micronutrients": {"calcium": "10mg per 100g", "iron": "0.5mg per 100g", "magnesium": "8mg per 100g"}, "bioactive_compounds": {"ephedrine": "0.8% concentration", "pseudoephedrine": "0.2% concentration", "tannins": "0.1% concentration"}, "bioavailability_notes": "Ephedrine and pseudoephedrine are well-absorbed in the gastrointestinal tract, but their effects can vary based on individual metabolism and existing health conditions. The presence of tannins may slightly inhibit the absorption of certain minerals."}
Reported Mechanism (Provisional)
Ephedrine in Maoto activates beta-2 adrenergic receptors in bronchial smooth muscle, causing bronchodilation and improved airflow. Cinnamaldehyde from cinnamon bark inhibits inflammatory cytokines like TNF-alpha and IL-6. Glycyrrhizin from licorice root modulates cortisol metabolism and enhances anti-inflammatory corticosteroid activity.
Clinical Narrative (Provisional)
A randomized controlled trial of 104 patients showed Maoto reduced fever duration by 1.2 days compared to standard care for influenza A. Another study of 67 subjects demonstrated 40% faster recovery from cold symptoms within 5 days. However, most clinical evidence comes from small Japanese studies with limited Western population data. More large-scale international trials are needed to confirm efficacy across diverse populations.
Also Known As
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