# Bifidobacterium animalis subsp. lactis Bi-07

**Canonical URL:** https://ingredients.hermeticasuperfoods.com/ingredients/bifidobacterium-animalis-subsp-lactis-bi-07
**Data Source:** Hermetica Superfoods Ingredient Encyclopedia
**Updated:** 2026-03-18
**Evidence Score:** 8 / 10
**Category:** Other
**Also Known As:** Bifidobacterium animalis subsp. lactis Bi-07, B. animalis subsp. lactis Bi-07, Bi-07 strain, B. lactis Bi-07, Bifidobacterium lactis Bi-07, Bifido Bi-07

## Overview

Bifidobacterium animalis subsp. lactis Bi-07 is a clinically studied probiotic strain that produces short-chain fatty acids, particularly acetate and lactate, which strengthen intestinal barrier function. This strain enhances [digestive health](/ingredients/condition/gut-health) by increasing beneficial bacterial populations and modulating immune responses through interaction with intestinal epithelial cells.

## Health Benefits

- Supports [digestive health](/ingredients/condition/gut-health) by promoting regular bowel movements, reducing constipation by 40%. This ensures a smoother digestive process. - Enhances [immune system](/ingredients/condition/immune-support) function by boosting the production of protective antibodies, reducing the incidence of infections. - May reduce [inflammation](/ingredients/condition/inflammation) by modulating immune responses, leading to decreased chronic inflammation markers. - Improves gut barrier function, preventing the entry of harmful pathogens and toxins. - Aids in nutrient absorption by maintaining a healthy gut lining, ensuring efficient uptake of vitamins and minerals. - Supports [mental health](/ingredients/condition/mood) by influencing the gut-brain axis, potentially reducing symptoms of depression. - Promotes [cardiovascular health](/ingredients/condition/heart-health) by lowering cholesterol levels, contributing to a healthier heart.

## Mechanism of Action

Bi-07 adheres to intestinal epithelial cells via specific adhesins, producing acetate and lactate that lower colonic pH and inhibit pathogenic bacteria growth. The strain stimulates dendritic cells and enhances secretory IgA production through toll-like receptor signaling pathways. It strengthens tight junction proteins like claudin-1 and occludin, improving [intestinal barrier integrity](/ingredients/condition/gut-health).

## Clinical Summary

Human clinical trials with sample sizes ranging from 60-200 participants demonstrate Bi-07's efficacy in reducing constipation by 40% and decreasing upper respiratory tract infections by 27%. Double-blind, placebo-controlled studies show significant improvements in stool frequency and consistency within 2-4 weeks at doses of 1-10 billion CFU daily. Evidence quality is moderate with most studies lasting 4-12 weeks, though longer-term safety data remains limited.

## Nutritional Profile

- Rich in [probiotic](/ingredients/condition/gut-health)s. - Supports gut health and [immunity](/ingredients/condition/immune-support). - Enhances nutrient absorption.

## Dosage & Preparation

Typical dosage ranges from 1 to 10 billion CFU per day. Consult a healthcare provider before use.

## Safety & Drug Interactions

Bi-07 is generally well-tolerated with mild gastrointestinal symptoms like bloating or gas occurring in less than 5% of users during the first week. No significant drug interactions have been reported, though immunocompromised individuals should consult healthcare providers before use. Safety during pregnancy and breastfeeding has not been established in clinical trials. Individuals with severe acute pancreatitis or compromised intestinal barrier function should avoid [probiotic](/ingredients/condition/gut-health) supplementation.

## Scientific Research

Research supports its role in improving [digestive health](/ingredients/condition/gut-health) and boosting [immunity](/ingredients/condition/immune-support), though further studies are needed to confirm other health claims.

## Historical & Cultural Context

This strain has been isolated from healthy human microbiota and has been used in various [probiotic](/ingredients/condition/gut-health) formulations.

## Synergistic Combinations

Lactobacillus plantarum Lp-115, Bifidobacterium longum SP 07/3, Streptococcus thermophilus TH-4

## Frequently Asked Questions

### What is the effective dosage of Bifidobacterium animalis subsp. lactis Bi-07?

Clinical studies show effective doses range from 1-10 billion CFU daily, with most benefits observed at 2-5 billion CFU. Higher doses do not necessarily provide additional benefits and may cause initial digestive discomfort.

### How long does it take for Bi-07 to improve digestive symptoms?

Most users experience improvements in bowel movement frequency within 1-2 weeks, with maximum benefits typically achieved after 4 weeks of consistent daily supplementation. Immune benefits may take 6-8 weeks to become apparent.

### Can Bi-07 survive stomach acid and reach the intestines alive?

Bi-07 demonstrates high acid tolerance and bile resistance, with survival rates exceeding 80% through simulated gastric conditions. The strain's natural protective mechanisms allow effective colonization of the large intestine.

### What foods contain Bifidobacterium animalis subsp. lactis Bi-07 naturally?

Bi-07 is not naturally found in foods but is added to specific probiotic yogurts, kefir products, and dietary supplements. Most dietary sources provide 1-10 billion CFU per serving when properly manufactured and stored.

### Is Bi-07 safe for children and elderly adults?

Clinical studies include participants aged 18-75, with good safety profiles observed across age groups. However, specific pediatric and geriatric dosing guidelines have not been established, so medical supervision is recommended for these populations.

### Does Bifidobacterium animalis subsp. lactis Bi-07 interact with antibiotics?

Bi-07 may be reduced or eliminated when taken concurrently with broad-spectrum antibiotics, as these medications kill both harmful and beneficial bacteria. It is generally recommended to take Bi-07 at least 2 hours apart from antibiotic doses, and to resume supplementation after the antibiotic course is complete to restore gut flora. Consult with your healthcare provider about the optimal timing for your specific antibiotic medication.

### Who benefits most from Bifidobacterium animalis subsp. lactis Bi-07 supplementation?

Bi-07 is particularly beneficial for individuals experiencing constipation, irregular bowel movements, or weakened digestive function, as clinical evidence shows it reduces constipation by approximately 40%. Those with compromised immune function or frequent infections may also benefit from its immune-boosting properties, which enhance antibody production. Additionally, people with chronic inflammation markers or irritable bowel conditions may experience benefits from its gut barrier-supporting and immunomodulating effects.

### How does Bifidobacterium animalis subsp. lactis Bi-07 compare to other Bifidobacterium strains?

Bi-07 is specifically selected for its superior acid tolerance and ability to survive gastric conditions better than many other Bifidobacterium strains, making it more effective at reaching the colon alive. Unlike some strains that primarily support general digestive health, Bi-07 has documented clinical evidence for reducing constipation and supporting immune function through antibody production. Each Bifidobacterium strain has different metabolic capabilities; Bi-07 is particularly noted for its anti-inflammatory and barrier-strengthening properties compared to strains that may only support basic digestive balance.

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*Source: Hermetica Superfoods Ingredient Encyclopedia — https://ingredients.hermeticasuperfoods.com*
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