Methadone Interactions

Name: Methadone Interactions
License: https://creativecommons.org/licenses/by-nc-sa/4.0/

492 known interactions for Methadone. Click any interaction for the full evidence-based breakdown.

🛑 Contraindicated (7)

Methadone + AlcoholCONTRAINDICATED — extremely dangerous combination
Methadone + AlprazolamCONTRAINDICATED — FDA Black Box Warning for respiratory death
Methadone + ClonazepamCONTRAINDICATED — FDA Black Box Warning
Methadone + DiazepamCONTRAINDICATED — FDA Black Box Warning
Methadone + HydrocodoneCONTRAINDICATED — never combine two full opioid agonists
Methadone + LorazepamCONTRAINDICATED — FDA Black Box Warning
Methadone + OxycodoneCONTRAINDICATED — dual full opioid agonists

⚠️ Major (3)

Methadone + DiphenhydramineDANGEROUS — additive respiratory depression
Methadone + OndansetronFDA labels warn about QT prolongation. ECG monitoring recommended. Consider alternative anti-emetics that do not prolong QT.
Methadone + RifampinFDA-documented interaction. Can precipitate opioid withdrawal. Methadone dose increases typically needed. Very careful monitoring required when starting and stopping rifampin.

✅ Safe (482)

Methadone + 5-HTP🟢 SAFE — 5-HTP and Methadone can be taken together safely.
Methadone + Acarbose🟢 SAFE — Methadone and Acarbose can be taken together safely.
Methadone + Acetaminophen🟢 SAFE — Acetaminophen and Methadone can be taken together safely.
Methadone + Acetyl-L-Carnitine🟢 SAFE — Acetyl-L-Carnitine and Methadone can be taken together safely.
Methadone + Activated Charcoal🟢 SAFE — Activated Charcoal and Methadone can be taken together safely.
Methadone + AdrafinilAdrafinil and Methadone — No Known Interaction
Methadone + Agmatine🟢 SAFE — Methadone and Agmatine can be taken together safely.
Methadone + Albuterol🟢 SAFE — Albuterol and Methadone can be taken together safely.
Methadone + Allopurinol🟢 SAFE — Allopurinol and Methadone can be taken together safely.
Methadone + Alpha-GPC🟢 SAFE — Methadone and Alpha-GPC can be taken together safely.
Methadone + Alpha-Lipoic Acid🟢 SAFE — Alpha-Lipoic Acid and Methadone can be taken together safely.
Methadone + Amiodarone🟢 SAFE — Methadone and Amiodarone can be taken together safely.
Methadone + Amitriptyline🟢 SAFE — Methadone and Amitriptyline can be taken together safely.
Methadone + Amlodipine🟢 SAFE — Amlodipine and Methadone can be taken together safely.
Methadone + Amoxicillin🟢 SAFE — Amoxicillin and Methadone can be taken together safely.
Methadone + Amoxicillin/Clavulanate🟢 SAFE — Methadone and Amoxicillin/Clavulanate can be taken together safely.
Methadone + Amphetamine/Dextroamphetamine🟢 SAFE — Amphetamine/Dextroamphetamine and Methadone can be taken together safely.
Methadone + Anastrozole🟢 SAFE — Methadone and Anastrozole can be taken together safely.
Methadone + Andrographis🟢 SAFE — Methadone and Andrographis can be taken together safely.
Methadone + ApigeninApigenin and Methadone — No Known Interaction
Methadone + Apixaban🟢 SAFE — Apixaban and Methadone can be taken together safely.
Methadone + Apple Cider Vinegar🟢 SAFE — Apple Cider Vinegar and Methadone can be taken together safely.
Methadone + Aripiprazole🟢 SAFE — Aripiprazole and Methadone can be taken together safely.
Methadone + Arnica🟢 SAFE — Methadone and Arnica can be taken together safely.
Methadone + Ashwagandha🟢 SAFE — Ashwagandha and Methadone can be taken together safely.
Methadone + Aspirin🟢 SAFE — Aspirin and Methadone can be taken together safely.
Methadone + Astaxanthin🟢 SAFE — Methadone and Astaxanthin can be taken together safely.
Methadone + Astragalus🟢 SAFE — Astragalus and Methadone can be taken together safely.
Methadone + Atenolol🟢 SAFE — Atenolol and Methadone can be taken together safely.
Methadone + Atomoxetine🟢 SAFE — Atomoxetine and Methadone can be taken together safely.
Methadone + Atorvastatin🟢 SAFE — Atorvastatin and Methadone can be taken together safely.
Methadone + Azathioprine🟢 SAFE — Methadone and Azathioprine can be taken together safely.
Methadone + Azithromycin🟢 SAFE — Azithromycin and Methadone can be taken together safely.
Methadone + Bacopa Monnieri🟢 SAFE — Bacopa Monnieri and Methadone can be taken together safely.
Methadone + Barberry🟢 SAFE — Methadone and Barberry can be taken together safely.
Methadone + Barley Grass🟢 SAFE — Methadone and Barley Grass can be taken together safely.
Methadone + BCAAs🟢 SAFE — BCAAs and Methadone can be taken together safely.
Methadone + Bee Pollen🟢 SAFE — Bee Pollen and Methadone can be taken together safely.
Methadone + Bee Propolis🟢 SAFE — Methadone and Bee Propolis can be taken together safely.
Methadone + Bentonite Clay🟢 SAFE — Methadone and Bentonite Clay can be taken together safely.
Methadone + Benzonatate🟢 SAFE — Methadone and Benzonatate can be taken together safely.
Methadone + Benzoyl Peroxide🟢 SAFE — Benzoyl Peroxide and Methadone can be taken together safely.
Methadone + Benztropine🟢 SAFE — Methadone and Benztropine can be taken together safely.
Methadone + Berberine🟢 SAFE — Berberine and Methadone can be taken together safely.
Methadone + Beta-Alanine🟢 SAFE — Beta-Alanine and Methadone can be taken together safely.
Methadone + Betaine HCl🟢 SAFE — Methadone and Betaine HCl can be taken together safely.
Methadone + Betaine TMG🟢 SAFE — Methadone and Betaine TMG can be taken together safely.
Methadone + Biotin🟢 SAFE — Biotin and Methadone can be taken together safely.
Methadone + Bismuth Subsalicylate🟢 SAFE — Bismuth Subsalicylate and Methadone can be taken together safely.
Methadone + Black Cohosh🟢 SAFE — Black Cohosh and Methadone can be taken together safely.
Methadone + Black Seed Oil🟢 SAFE — Black Seed Oil and Methadone can be taken together safely.
Methadone + Black Tea🟢 SAFE — Methadone and Black Tea can be taken together safely.
Methadone + Black Walnut HullBlack Walnut Hull and Methadone — No Known Interaction
Methadone + Blue Lotus🟢 SAFE — Methadone and Blue Lotus can be taken together safely.
Methadone + Bone Broth Protein🟢 SAFE — Methadone and Bone Broth Protein can be taken together safely.
Methadone + Boron🟢 SAFE — Boron and Methadone can be taken together safely.
Methadone + Boswellia🟢 SAFE — Boswellia and Methadone can be taken together safely.
Methadone + BPC-157🟢 SAFE — BPC-157 and Methadone can be taken together safely.
Methadone + Brexpiprazole🟢 SAFE — Methadone and Brexpiprazole can be taken together safely.
Methadone + Brivaracetam🟢 SAFE — Methadone and Brivaracetam can be taken together safely.
Methadone + Bromelain🟢 SAFE — Bromelain and Methadone can be taken together safely.
Methadone + Bromocriptine🟢 SAFE — Methadone and Bromocriptine can be taken together safely.
Methadone + Budesonide🟢 SAFE — Budesonide and Methadone can be taken together safely.
Methadone + Buprenorphine🟢 SAFE — Methadone and Buprenorphine can be taken together safely.
Methadone + Bupropion🟢 SAFE — Bupropion and Methadone can be taken together safely.
Methadone + Buspirone🟢 SAFE — Buspirone and Methadone can be taken together safely.
Methadone + Butterbur🟢 SAFE — Methadone and Butterbur can be taken together safely.
Methadone + Cabergoline🟢 SAFE — Methadone and Cabergoline can be taken together safely.
Methadone + Caffeine🟢 SAFE — Caffeine and Methadone can be taken together safely.
Methadone + Caffeine Anhydrous🟢 SAFE — Caffeine Anhydrous and Methadone can be taken together safely.
Methadone + Calcium🟢 SAFE — Calcium and Methadone can be taken together safely.
Methadone + Calcium Carbonate🟢 SAFE — Calcium Carbonate and Methadone can be taken together safely.
Methadone + California Poppy🟢 SAFE — Methadone and California Poppy can be taken together safely.
Methadone + Canagliflozin🟢 SAFE — Methadone and Canagliflozin can be taken together safely.
Methadone + Carbamazepine🟢 SAFE — Methadone and Carbamazepine can be taken together safely.
Methadone + Cariprazine🟢 SAFE — Methadone and Cariprazine can be taken together safely.
Methadone + Carvedilol🟢 SAFE — Carvedilol and Methadone can be taken together safely.
Methadone + Casein Protein🟢 SAFE — Casein Protein and Methadone can be taken together safely.
Methadone + Cat's Claw🟢 SAFE — Cat's Claw and Methadone can be taken together safely.
Methadone + Cayenne🟢 SAFE — Cayenne and Methadone can be taken together safely.
Methadone + CBD Oil🟢 SAFE — CBD Oil and Methadone can be taken together safely.
Methadone + CDP-Choline🟢 SAFE — Methadone and CDP-Choline can be taken together safely.
Methadone + Celecoxib🟢 SAFE — Celecoxib and Methadone can be taken together safely.
Methadone + Cephalexin🟢 SAFE — Cephalexin and Methadone can be taken together safely.
Methadone + Cetirizine🟢 SAFE — Cetirizine and Methadone can be taken together safely.
Methadone + Chaga🟢 SAFE — Chaga and Methadone can be taken together safely.
Methadone + Chamomile🟢 SAFE — Chamomile and Methadone can be taken together safely.
Methadone + Chia Seeds🟢 SAFE — Methadone and Chia Seeds can be taken together safely.
Methadone + Chlorella🟢 SAFE — Chlorella and Methadone can be taken together safely.
Methadone + Chlorophyll🟢 SAFE — Methadone and Chlorophyll can be taken together safely.
Methadone + Choline🟢 SAFE — Methadone and Choline can be taken together safely.
Methadone + Chondroitin🟢 SAFE — Chondroitin and Methadone can be taken together safely.
Methadone + Chromium🟢 SAFE — Chromium and Methadone can be taken together safely.
Methadone + Cinnamon Extract🟢 SAFE — Cinnamon Extract and Methadone can be taken together safely.
Methadone + Ciprofloxacin🟢 SAFE — Ciprofloxacin and Methadone can be taken together safely.
Methadone + CistancheCistanche and Methadone — No Known Interaction
Methadone + Citalopram🟢 SAFE — Citalopram and Methadone can be taken together safely.
Methadone + Citrulline🟢 SAFE — Citrulline and Methadone can be taken together safely.
Methadone + Clarithromycin🟢 SAFE — Methadone and Clarithromycin can be taken together safely.
Methadone + Clindamycin🟢 SAFE — Clindamycin and Methadone can be taken together safely.
Methadone + Clomipramine🟢 SAFE — Methadone and Clomipramine can be taken together safely.
Methadone + Clonidine🟢 SAFE — Clonidine and Methadone can be taken together safely.
Methadone + Clopidogrel🟢 SAFE — Clopidogrel and Methadone can be taken together safely.
Methadone + Clove OilClove Oil and Methadone — No Known Interaction
Methadone + Clozapine🟢 SAFE — Methadone and Clozapine can be taken together safely.
Methadone + Coconut Oil🟢 SAFE — Methadone and Coconut Oil can be taken together safely.
Methadone + Coffee🟢 SAFE — Methadone and Coffee can be taken together safely.
Methadone + Colchicine🟢 SAFE — Colchicine and Methadone can be taken together safely.
Methadone + Collagen🟢 SAFE — Collagen and Methadone can be taken together safely.
Methadone + Colloidal SilverColloidal Silver and Methadone — No Known Interaction
Methadone + Colostrum🟢 SAFE — Colostrum and Methadone can be taken together safely.
Methadone + Combined Oral Contraceptives🟢 SAFE — Combined Oral Contraceptives and Methadone can be taken together safely.
Methadone + Comfrey🟢 SAFE — Methadone and Comfrey can be taken together safely.
Methadone + Copper🟢 SAFE — Copper and Methadone can be taken together safely.
Methadone + CoQ10🟢 SAFE — CoQ10 and Methadone can be taken together safely.
Methadone + Cordyceps🟢 SAFE — Cordyceps and Methadone can be taken together safely.
Methadone + Cranberry Extract🟢 SAFE — Cranberry Extract and Methadone can be taken together safely.
Methadone + Creatine🟢 SAFE — Creatine and Methadone can be taken together safely.
Methadone + Cyclobenzaprine🟢 SAFE — Cyclobenzaprine and Methadone can be taken together safely.
Methadone + Cyclosporine🟢 SAFE — Methadone and Cyclosporine can be taken together safely.
Methadone + D-Aspartic Acid🟢 SAFE — D-Aspartic Acid and Methadone can be taken together safely.
Methadone + D-Mannose🟢 SAFE — D-Mannose and Methadone can be taken together safely.
Methadone + Dairy🟢 SAFE — Dairy and Methadone can be taken together safely.
Methadone + Damiana🟢 SAFE — Methadone and Damiana can be taken together safely.
Methadone + Dandelion Root🟢 SAFE — Dandelion Root and Methadone can be taken together safely.
Methadone + Dapagliflozin🟢 SAFE — Dapagliflozin and Methadone can be taken together safely.
Methadone + Dapsone🟢 SAFE — Methadone and Dapsone can be taken together safely.
Methadone + Dark Chocolate🟢 SAFE — Dark Chocolate and Methadone can be taken together safely.
Methadone + Desiccated Thyroid🟢 SAFE — Desiccated Thyroid and Methadone can be taken together safely.
Methadone + Desvenlafaxine🟢 SAFE — Desvenlafaxine and Methadone can be taken together safely.
Methadone + Devil's Claw🟢 SAFE — Methadone and Devil's Claw can be taken together safely.
Methadone + Dexamethasone🟢 SAFE — Methadone and Dexamethasone can be taken together safely.
Methadone + Dextromethorphan🟢 SAFE — Dextromethorphan and Methadone can be taken together safely.
Methadone + DHEA🟢 SAFE — DHEA and Methadone can be taken together safely.
Methadone + Diatomaceous Earth🟢 SAFE — Methadone and Diatomaceous Earth can be taken together safely.
Methadone + Diclofenac🟢 SAFE — Methadone and Diclofenac can be taken together safely.
Methadone + Dicloxacillin🟢 SAFE — Methadone and Dicloxacillin can be taken together safely.
Methadone + Dicyclomine🟢 SAFE — Methadone and Dicyclomine can be taken together safely.
Methadone + Digestive Enzymes🟢 SAFE — Digestive Enzymes and Methadone can be taken together safely.
Methadone + Digoxin🟢 SAFE — Methadone and Digoxin can be taken together safely.
Methadone + Diindolylmethane🟢 SAFE — Methadone and Diindolylmethane can be taken together safely.
Methadone + Diltiazem🟢 SAFE — Diltiazem and Methadone can be taken together safely.
Methadone + DIM🟢 SAFE — DIM and Methadone can be taken together safely.
Methadone + DMSO🟢 SAFE — DMSO and Methadone can be taken together safely.
Methadone + Docusate🟢 SAFE — Docusate and Methadone can be taken together safely.
Methadone + Donepezil🟢 SAFE — Methadone and Donepezil can be taken together safely.
Methadone + Dong Quai🟢 SAFE — Dong Quai and Methadone can be taken together safely.
Methadone + Doxazosin🟢 SAFE — Methadone and Doxazosin can be taken together safely.
Methadone + Doxepin🟢 SAFE — Methadone and Doxepin can be taken together safely.
Methadone + Doxycycline🟢 SAFE — Doxycycline and Methadone can be taken together safely.
Methadone + Duloxetine🟢 SAFE — Duloxetine and Methadone can be taken together safely.
Methadone + Echinacea🟢 SAFE — Echinacea and Methadone can be taken together safely.
Methadone + Elderberry🟢 SAFE — Elderberry and Methadone can be taken together safely.
Methadone + Electrolyte Complex🟢 SAFE — Electrolyte Complex and Methadone can be taken together safely.
Methadone + EmodinEmodin and Methadone — No Known Interaction
Methadone + Empagliflozin🟢 SAFE — Empagliflozin and Methadone can be taken together safely.
Methadone + Enalapril🟢 SAFE — Enalapril and Methadone can be taken together safely.
Methadone + Energy Drinks🟢 SAFE — Methadone and Energy Drinks can be taken together safely.
Methadone + Erythromycin🟢 SAFE — Methadone and Erythromycin can be taken together safely.
Methadone + Escitalopram🟢 SAFE — Escitalopram and Methadone can be taken together safely.
Methadone + Eslicarbazepine🟢 SAFE — Methadone and Eslicarbazepine can be taken together safely.
Methadone + Esomeprazole🟢 SAFE — Esomeprazole and Methadone can be taken together safely.
Methadone + Estradiol🟢 SAFE — Estradiol and Methadone can be taken together safely.
Methadone + Evening Primrose Oil🟢 SAFE — Evening Primrose Oil and Methadone can be taken together safely.
Methadone + Ezetimibe🟢 SAFE — Methadone and Ezetimibe can be taken together safely.
Methadone + Fadogia AgrestisFadogia Agrestis and Methadone — No Known Interaction
Methadone + Famotidine🟢 SAFE — Famotidine and Methadone can be taken together safely.
Methadone + Febuxostat🟢 SAFE — Methadone and Febuxostat can be taken together safely.
Methadone + Fenofibrate🟢 SAFE — Methadone and Fenofibrate can be taken together safely.
Methadone + Fenugreek🟢 SAFE — Fenugreek and Methadone can be taken together safely.
Methadone + Fermented Foods🟢 SAFE — Fermented Foods and Methadone can be taken together safely.
Methadone + Fermented Vegetables🟢 SAFE — Methadone and Fermented Vegetables can be taken together safely.
Methadone + Feverfew🟢 SAFE — Methadone and Feverfew can be taken together safely.
Methadone + Finasteride🟢 SAFE — Finasteride and Methadone can be taken together safely.
Methadone + Flaxseed🟢 SAFE — Methadone and Flaxseed can be taken together safely.
Methadone + Flecainide🟢 SAFE — Methadone and Flecainide can be taken together safely.
Methadone + Fluconazole🟢 SAFE — Fluconazole and Methadone can be taken together safely.
Methadone + Fludrocortisone🟢 SAFE — Methadone and Fludrocortisone can be taken together safely.
Methadone + Fluoxetine🟢 SAFE — Fluoxetine and Methadone can be taken together safely.
Methadone + Fluticasone🟢 SAFE — Methadone and Fluticasone can be taken together safely.
Methadone + Fluvoxamine🟢 SAFE — Fluvoxamine and Methadone can be taken together safely.
Methadone + Folate🟢 SAFE — Folate and Methadone can be taken together safely.
Methadone + Fosfomycin🟢 SAFE — Methadone and Fosfomycin can be taken together safely.
Methadone + Furosemide🟢 SAFE — Furosemide and Methadone can be taken together safely.
Methadone + GABA🟢 SAFE — GABA and Methadone can be taken together safely.
Methadone + Gabapentin🟢 SAFE — Gabapentin and Methadone can be taken together safely.
Methadone + Garlic Extract🟢 SAFE — Garlic Extract and Methadone can be taken together safely.
Methadone + Germanium🟢 SAFE — Methadone and Germanium can be taken together safely.
Methadone + Ginger🟢 SAFE — Ginger and Methadone can be taken together safely.
Methadone + Ginkgo Biloba🟢 SAFE — Ginkgo Biloba and Methadone can be taken together safely.
Methadone + Ginseng (Panax)🟢 SAFE — Ginseng (Panax) and Methadone can be taken together safely.
Methadone + Glimepiride🟢 SAFE — Methadone and Glimepiride can be taken together safely.
Methadone + Glipizide🟢 SAFE — Glipizide and Methadone can be taken together safely.
Methadone + Glucosamine🟢 SAFE — Glucosamine and Methadone can be taken together safely.
Methadone + Glycine🟢 SAFE — Glycine and Methadone can be taken together safely.
Methadone + Golden Milk🟢 SAFE — Methadone and Golden Milk can be taken together safely.
Methadone + Goldenseal🟢 SAFE — Methadone and Goldenseal can be taken together safely.
Methadone + Gotu Kola🟢 SAFE — Gotu Kola and Methadone can be taken together safely.
Methadone + Grape Seed Extract🟢 SAFE — Grape Seed Extract and Methadone can be taken together safely.
Methadone + Grapefruit🟢 SAFE — Grapefruit and Methadone can be taken together safely.
Methadone + Green Tea🟢 SAFE — Green Tea and Methadone can be taken together safely.
Methadone + Growth Hormone🟢 SAFE — Growth Hormone and Methadone can be taken together safely.
Methadone + Guaifenesin🟢 SAFE — Guaifenesin and Methadone can be taken together safely.
Methadone + Guanfacine🟢 SAFE — Guanfacine and Methadone can be taken together safely.
Methadone + Guarana🟢 SAFE — Methadone and Guarana can be taken together safely.
Methadone + Hawthorn Berry🟢 SAFE — Hawthorn Berry and Methadone can be taken together safely.
Methadone + Hemp Seeds🟢 SAFE — Methadone and Hemp Seeds can be taken together safely.
Methadone + Hibiscus🟢 SAFE — Hibiscus and Methadone can be taken together safely.
Methadone + HMB🟢 SAFE — HMB and Methadone can be taken together safely.
Methadone + Holy Basil🟢 SAFE — Holy Basil and Methadone can be taken together safely.
Methadone + Hops Extract🟢 SAFE — Methadone and Hops Extract can be taken together safely.
Methadone + Horny Goat Weed🟢 SAFE — Methadone and Horny Goat Weed can be taken together safely.
Methadone + Hydralazine🟢 SAFE — Methadone and Hydralazine can be taken together safely.
Methadone + Hydrochlorothiazide🟢 SAFE — Hydrochlorothiazide and Methadone can be taken together safely.
Methadone + Hydrocortisone🟢 SAFE — Hydrocortisone and Methadone can be taken together safely.
Methadone + Hydroxychloroquine🟢 SAFE — Methadone and Hydroxychloroquine can be taken together safely.
Methadone + Hydroxyzine🟢 SAFE — Hydroxyzine and Methadone can be taken together safely.
Methadone + Ibuprofen🟢 SAFE — Ibuprofen and Methadone can be taken together safely.
Methadone + Indomethacin🟢 SAFE — Methadone and Indomethacin can be taken together safely.
Methadone + Inositol🟢 SAFE — Methadone and Inositol can be taken together safely.
Methadone + Insulin (all forms)🟢 SAFE — Insulin (all forms) and Methadone can be taken together safely.
Methadone + Iodine🟢 SAFE — Iodine and Methadone can be taken together safely.
Methadone + Iron🟢 SAFE — Iron and Methadone can be taken together safely.
Methadone + Isoniazid🟢 SAFE — Methadone and Isoniazid can be taken together safely.
Methadone + Isosorbide Mononitrate🟢 SAFE — Methadone and Isosorbide Mononitrate can be taken together safely.
Methadone + Isotretinoin🟢 SAFE — Methadone and Isotretinoin can be taken together safely.
Methadone + Ivabradine🟢 SAFE — Methadone and Ivabradine can be taken together safely.
Methadone + Kanna🟢 SAFE — Methadone and Kanna can be taken together safely.
Methadone + Kava🟢 SAFE — Kava and Methadone can be taken together safely.
Methadone + Ketorolac🟢 SAFE — Methadone and Ketorolac can be taken together safely.
Methadone + Kola Nut🟢 SAFE — Methadone and Kola Nut can be taken together safely.
Methadone + Kombucha🟢 SAFE — Methadone and Kombucha can be taken together safely.
Methadone + Kratom🟢 SAFE — Kratom and Methadone can be taken together safely.
Methadone + L-Arginine🟢 SAFE — L-Arginine and Methadone can be taken together safely.
Methadone + L-Carnosine🟢 SAFE — L-Carnosine and Methadone can be taken together safely.
Methadone + L-Citrulline Malate🟢 SAFE — Methadone and L-Citrulline Malate can be taken together safely.
Methadone + L-Dopa🟢 SAFE — Methadone and L-Dopa can be taken together safely.
Methadone + L-Glutamine🟢 SAFE — L-Glutamine and Methadone can be taken together safely.
Methadone + L-Histidine🟢 SAFE — Methadone and L-Histidine can be taken together safely.
Methadone + L-Lysine🟢 SAFE — Methadone and L-Lysine can be taken together safely.
Methadone + L-Methionine🟢 SAFE — Methadone and L-Methionine can be taken together safely.
Methadone + L-Ornithine🟢 SAFE — Methadone and L-Ornithine can be taken together safely.
Methadone + L-Serine🟢 SAFE — Methadone and L-Serine can be taken together safely.
Methadone + L-Theanine🟢 SAFE — L-Theanine and Methadone can be taken together safely.
Methadone + L-Tryptophan🟢 SAFE — Methadone and L-Tryptophan can be taken together safely.
Methadone + Lactulose🟢 SAFE — Methadone and Lactulose can be taken together safely.
Methadone + Lamotrigine🟢 SAFE — Lamotrigine and Methadone can be taken together safely.
Methadone + Leflunomide🟢 SAFE — Methadone and Leflunomide can be taken together safely.
Methadone + Lemon Balm🟢 SAFE — Lemon Balm and Methadone can be taken together safely.
Methadone + Letrozole🟢 SAFE — Methadone and Letrozole can be taken together safely.
Methadone + Levetiracetam🟢 SAFE — Methadone and Levetiracetam can be taken together safely.
Methadone + Levodopa🟢 SAFE — Methadone and Levodopa can be taken together safely.
Methadone + Levodopa-Carbidopa🟢 SAFE — Methadone and Levodopa-Carbidopa can be taken together safely.
Methadone + Levofloxacin🟢 SAFE — Methadone and Levofloxacin can be taken together safely.
Methadone + Levothyroxine🟢 SAFE — Levothyroxine and Methadone can be taken together safely.
Methadone + Licorice Root🟢 SAFE — Licorice Root and Methadone can be taken together safely.
Methadone + Linaclotide🟢 SAFE — Methadone and Linaclotide can be taken together safely.
Methadone + Linagliptin🟢 SAFE — Linagliptin and Methadone can be taken together safely.
Methadone + Linezolid🟢 SAFE — Methadone and Linezolid can be taken together safely.
Methadone + Lions Mane🟢 SAFE — Lions Mane and Methadone can be taken together safely.
Methadone + Liraglutide🟢 SAFE — Methadone and Liraglutide can be taken together safely.
Methadone + Lisdexamfetamine🟢 SAFE — Lisdexamfetamine and Methadone can be taken together safely.
Methadone + Lisinopril🟢 SAFE — Lisinopril and Methadone can be taken together safely.
Methadone + Lithium🟢 SAFE — Lithium and Methadone can be taken together safely.
Methadone + Lithium Orotate🟢 SAFE — Methadone and Lithium Orotate can be taken together safely.
Methadone + Loperamide🟢 SAFE — Loperamide and Methadone can be taken together safely.
Methadone + Loratadine🟢 SAFE — Loratadine and Methadone can be taken together safely.
Methadone + Losartan🟢 SAFE — Losartan and Methadone can be taken together safely.
Methadone + Lovastatin🟢 SAFE — Lovastatin and Methadone can be taken together safely.
Methadone + Lubiprostone🟢 SAFE — Methadone and Lubiprostone can be taken together safely.
Methadone + LumbrokinaseLumbrokinase and Methadone — No Known Interaction
Methadone + Lurasidone🟢 SAFE — Methadone and Lurasidone can be taken together safely.
Methadone + Lutein🟢 SAFE — Lutein and Methadone can be taken together safely.
Methadone + Lycopene🟢 SAFE — Lycopene and Methadone can be taken together safely.
Methadone + Maca Root🟢 SAFE — Maca Root and Methadone can be taken together safely.
Methadone + Magnesium🟢 SAFE — Magnesium and Methadone can be taken together safely.
Methadone + Magnesium Hydroxide🟢 SAFE — Magnesium Hydroxide and Methadone can be taken together safely.
Methadone + Magnolia Bark🟢 SAFE — Methadone and Magnolia Bark can be taken together safely.
Methadone + Manganese🟢 SAFE — Methadone and Manganese can be taken together safely.
Methadone + Marshmallow Root🟢 SAFE — Methadone and Marshmallow Root can be taken together safely.
Methadone + Matcha🟢 SAFE — Methadone and Matcha can be taken together safely.
Methadone + MCT Oil🟢 SAFE — MCT Oil and Methadone can be taken together safely.
Methadone + Meclizine🟢 SAFE — Meclizine and Methadone can be taken together safely.
Methadone + Melatonin🟢 SAFE — Melatonin and Methadone can be taken together safely.
Methadone + Melatonin Extended Release🟢 SAFE — Melatonin Extended Release and Methadone can be taken together safely.
Methadone + Meloxicam🟢 SAFE — Methadone and Meloxicam can be taken together safely.
Methadone + Memantine🟢 SAFE — Methadone and Memantine can be taken together safely.
Methadone + Metformin🟢 SAFE — Metformin and Methadone can be taken together safely.
Methadone + Methotrexate🟢 SAFE — Methotrexate and Methadone can be taken together safely.
Methadone + Methylphenidate🟢 SAFE — Methylphenidate and Methadone can be taken together safely.
Methadone + Methylprednisolone🟢 SAFE — Methylprednisolone and Methadone can be taken together safely.
Methadone + Metoclopramide🟢 SAFE — Methadone and Metoclopramide can be taken together safely.
Methadone + Metoprolol🟢 SAFE — Metoprolol and Methadone can be taken together safely.
Methadone + Metronidazole🟢 SAFE — Metronidazole and Methadone can be taken together safely.
Methadone + Milk Thistle🟢 SAFE — Milk Thistle and Methadone can be taken together safely.
Methadone + Minocycline🟢 SAFE — Methadone and Minocycline can be taken together safely.
Methadone + Minoxidil🟢 SAFE — Minoxidil and Methadone can be taken together safely.
Methadone + Mirtazapine🟢 SAFE — Mirtazapine and Methadone can be taken together safely.
Methadone + Misoprostol🟢 SAFE — Methadone and Misoprostol can be taken together safely.
Methadone + Modafinil🟢 SAFE — Modafinil and Methadone can be taken together safely.
Methadone + Molybdenum🟢 SAFE — Methadone and Molybdenum can be taken together safely.
Methadone + MonolaurinMonolaurin and Methadone — No Known Interaction
Methadone + Montelukast🟢 SAFE — Montelukast and Methadone can be taken together safely.
Methadone + Moringa🟢 SAFE — Moringa and Methadone can be taken together safely.
Methadone + Moxifloxacin🟢 SAFE — Methadone and Moxifloxacin can be taken together safely.
Methadone + Mucuna Pruriens🟢 SAFE — Mucuna Pruriens and Methadone can be taken together safely.
Methadone + Muira Puama🟢 SAFE — Methadone and Muira Puama can be taken together safely.
Methadone + Mycophenolate🟢 SAFE — Methadone and Mycophenolate can be taken together safely.
Methadone + NAC🟢 SAFE — NAC and Methadone can be taken together safely.
Methadone + Naloxone🟢 SAFE — Methadone and Naloxone can be taken together safely.
Methadone + Naltrexone🟢 SAFE — Methadone and Naltrexone can be taken together safely.
Methadone + Naproxen🟢 SAFE — Naproxen and Methadone can be taken together safely.
Methadone + NattokinaseNattokinase and Methadone — No Known Interaction
Methadone + Neem🟢 SAFE — Neem and Methadone can be taken together safely.
Methadone + Nettle Root🟢 SAFE — Nettle Root and Methadone can be taken together safely.
Methadone + Niacin Rx🟢 SAFE — Methadone and Niacin Rx can be taken together safely.
Methadone + Nicotinamide Riboside🟢 SAFE — Methadone and Nicotinamide Riboside can be taken together safely.
Methadone + Nicotine🟢 SAFE — Methadone and Nicotine can be taken together safely.
Methadone + Nifedipine🟢 SAFE — Nifedipine and Methadone can be taken together safely.
Methadone + Nitric Oxide Boosters🟢 SAFE — Nitric Oxide Boosters and Methadone can be taken together safely.
Methadone + Nitrofurantoin🟢 SAFE — Nitrofurantoin and Methadone can be taken together safely.
Methadone + Nitroglycerin🟢 SAFE — Methadone and Nitroglycerin can be taken together safely.
Methadone + NMN🟢 SAFE — Methadone and NMN can be taken together safely.
Methadone + Nortriptyline🟢 SAFE — Methadone and Nortriptyline can be taken together safely.
Methadone + Octreotide🟢 SAFE — Methadone and Octreotide can be taken together safely.
Methadone + Olanzapine🟢 SAFE — Methadone and Olanzapine can be taken together safely.
Methadone + Olive Leaf Extract🟢 SAFE — Olive Leaf Extract and Methadone can be taken together safely.
Methadone + Olmesartan🟢 SAFE — Olmesartan and Methadone can be taken together safely.
Methadone + Omega-3 Fish Oil🟢 SAFE — Omega-3 Fish Oil and Methadone can be taken together safely.
Methadone + Omeprazole🟢 SAFE — Omeprazole and Methadone can be taken together safely.
Methadone + Oregano Oil🟢 SAFE — Oregano Oil and Methadone can be taken together safely.
Methadone + Oregon Grape Root🟢 SAFE — Methadone and Oregon Grape Root can be taken together safely.
Methadone + Orlistat🟢 SAFE — Methadone and Orlistat can be taken together safely.
Methadone + Ox Bile🟢 SAFE — Methadone and Ox Bile can be taken together safely.
Methadone + Oxcarbazepine🟢 SAFE — Methadone and Oxcarbazepine can be taken together safely.
Methadone + Oxytocin🟢 SAFE — Oxytocin and Methadone can be taken together safely.
Methadone + Paliperidone🟢 SAFE — Methadone and Paliperidone can be taken together safely.
Methadone + Pantoprazole🟢 SAFE — Pantoprazole and Methadone can be taken together safely.
Methadone + Paroxetine🟢 SAFE — Paroxetine and Methadone can be taken together safely.
Methadone + Passionflower🟢 SAFE — Passionflower and Methadone can be taken together safely.
Methadone + Pau d'Arco🟢 SAFE — Methadone and Pau d'Arco can be taken together safely.
Methadone + PEA🟢 SAFE — PEA and Methadone can be taken together safely.
Methadone + Penicillamine🟢 SAFE — Methadone and Penicillamine can be taken together safely.
Methadone + Penicillin V🟢 SAFE — Methadone and Penicillin V can be taken together safely.
Methadone + Peppermint🟢 SAFE — Peppermint and Methadone can be taken together safely.
Methadone + Phenazopyridine🟢 SAFE — Phenazopyridine and Methadone can be taken together safely.
Methadone + PhenibutPhenibut and Methadone — No Known Interaction
Methadone + Phentermine🟢 SAFE — Methadone and Phentermine can be taken together safely.
Methadone + Phenylephrine🟢 SAFE — Phenylephrine and Methadone can be taken together safely.
Methadone + Phenylethylamine🟢 SAFE — Methadone and Phenylethylamine can be taken together safely.
Methadone + Phenytoin🟢 SAFE — Methadone and Phenytoin can be taken together safely.
Methadone + Phosphatidylserine🟢 SAFE — Phosphatidylserine and Methadone can be taken together safely.
Methadone + Pine Bark Extract🟢 SAFE — Pine Bark Extract and Methadone can be taken together safely.
Methadone + Pioglitazone🟢 SAFE — Pioglitazone and Methadone can be taken together safely.
Methadone + Piroxicam🟢 SAFE — Methadone and Piroxicam can be taken together safely.
Methadone + Polyethylene Glycol🟢 SAFE — Polyethylene Glycol and Methadone can be taken together safely.
Methadone + Pomegranate🟢 SAFE — Pomegranate and Methadone can be taken together safely.
Methadone + Potassium🟢 SAFE — Potassium and Methadone can be taken together safely.
Methadone + PQQ🟢 SAFE — Methadone and PQQ can be taken together safely.
Methadone + Pramipexole🟢 SAFE — Methadone and Pramipexole can be taken together safely.
Methadone + Pravastatin🟢 SAFE — Pravastatin and Methadone can be taken together safely.
Methadone + Pre-Workout Complex🟢 SAFE — Pre-Workout Complex and Methadone can be taken together safely.
Methadone + Prednisone🟢 SAFE — Prednisone and Methadone can be taken together safely.
Methadone + Pregabalin🟢 SAFE — Pregabalin and Methadone can be taken together safely.
Methadone + Pregnenolone🟢 SAFE — Pregnenolone and Methadone can be taken together safely.
Methadone + Probiotics🟢 SAFE — Probiotics and Methadone can be taken together safely.
Methadone + Progesterone🟢 SAFE — Progesterone and Methadone can be taken together safely.
Methadone + Propranolol🟢 SAFE — Propranolol and Methadone can be taken together safely.
Methadone + Protein Powder🟢 SAFE — Protein Powder and Methadone can be taken together safely.
Methadone + Pseudoephedrine🟢 SAFE — Pseudoephedrine and Methadone can be taken together safely.
Methadone + Quercetin🟢 SAFE — Quercetin and Methadone can be taken together safely.
Methadone + Quetiapine🟢 SAFE — Quetiapine and Methadone can be taken together safely.
Methadone + Raloxifene🟢 SAFE — Methadone and Raloxifene can be taken together safely.
Methadone + Ramipril🟢 SAFE — Ramipril and Methadone can be taken together safely.
Methadone + Ranitidine🟢 SAFE — Ranitidine and Methadone can be taken together safely.
Methadone + Ranolazine🟢 SAFE — Methadone and Ranolazine can be taken together safely.
Methadone + Rasagiline🟢 SAFE — Methadone and Rasagiline can be taken together safely.
Methadone + Raw Cacao🟢 SAFE — Methadone and Raw Cacao can be taken together safely.
Methadone + Reishi🟢 SAFE — Reishi and Methadone can be taken together safely.
Methadone + Resveratrol🟢 SAFE — Resveratrol and Methadone can be taken together safely.
Methadone + Rhodiola Rosea🟢 SAFE — Rhodiola Rosea and Methadone can be taken together safely.
Methadone + Rifaximin🟢 SAFE — Methadone and Rifaximin can be taken together safely.
Methadone + Risperidone🟢 SAFE — Methadone and Risperidone can be taken together safely.
Methadone + Rivaroxaban🟢 SAFE — Rivaroxaban and Methadone can be taken together safely.
Methadone + Roflumilast🟢 SAFE — Methadone and Roflumilast can be taken together safely.
Methadone + Ropinirole🟢 SAFE — Methadone and Ropinirole can be taken together safely.
Methadone + Rosuvastatin🟢 SAFE — Rosuvastatin and Methadone can be taken together safely.
Methadone + Royal Jelly🟢 SAFE — Royal Jelly and Methadone can be taken together safely.
Methadone + Sacubitril/Valsartan🟢 SAFE — Methadone and Sacubitril/Valsartan can be taken together safely.
Methadone + Salicylic Acid🟢 SAFE — Salicylic Acid and Methadone can be taken together safely.
Methadone + SAMe🟢 SAFE — SAMe and Methadone can be taken together safely.
Methadone + Saw Palmetto🟢 SAFE — Saw Palmetto and Methadone can be taken together safely.
Methadone + Sea MossSea Moss and Methadone — No Known Interaction
Methadone + Selegiline🟢 SAFE — Methadone and Selegiline can be taken together safely.
Methadone + Selenium🟢 SAFE — Selenium and Methadone can be taken together safely.
Methadone + Semaglutide🟢 SAFE — Semaglutide and Methadone can be taken together safely.
Methadone + SerrapeptaseSerrapeptase and Methadone — No Known Interaction
Methadone + Sertraline🟢 SAFE — Sertraline and Methadone can be taken together safely.
Methadone + Shatavari🟢 SAFE — Shatavari and Methadone can be taken together safely.
Methadone + Shilajit🟢 SAFE — Shilajit and Methadone can be taken together safely.
Methadone + Sildenafil🟢 SAFE — Sildenafil and Methadone can be taken together safely.
Methadone + Silica🟢 SAFE — Methadone and Silica can be taken together safely.
Methadone + Simethicone🟢 SAFE — Simethicone and Methadone can be taken together safely.
Methadone + Simvastatin🟢 SAFE — Simvastatin and Methadone can be taken together safely.
Methadone + Sitagliptin🟢 SAFE — Sitagliptin and Methadone can be taken together safely.
Methadone + Skullcap🟢 SAFE — Skullcap and Methadone can be taken together safely.
Methadone + Slippery Elm🟢 SAFE — Methadone and Slippery Elm can be taken together safely.
Methadone + Sotalol🟢 SAFE — Methadone and Sotalol can be taken together safely.
Methadone + Soy🟢 SAFE — Soy and Methadone can be taken together safely.
Methadone + SpermidineSpermidine and Methadone — No Known Interaction
Methadone + Spironolactone🟢 SAFE — Spironolactone and Methadone can be taken together safely.
Methadone + Spirulina🟢 SAFE — Spirulina and Methadone can be taken together safely.
Methadone + St. Johns Wort🟢 SAFE — St. Johns Wort and Methadone can be taken together safely.
Methadone + Strontium🟢 SAFE — Methadone and Strontium can be taken together safely.
Methadone + Sucralfate🟢 SAFE — Methadone and Sucralfate can be taken together safely.
Methadone + Sulfasalazine🟢 SAFE — Methadone and Sulfasalazine can be taken together safely.
Methadone + Sulforaphane🟢 SAFE — Methadone and Sulforaphane can be taken together safely.
Methadone + Sumatriptan🟢 SAFE — Sumatriptan and Methadone can be taken together safely.
Methadone + Tacrolimus🟢 SAFE — Tacrolimus and Methadone can be taken together safely.
Methadone + Tadalafil🟢 SAFE — Tadalafil and Methadone can be taken together safely.
Methadone + Tamoxifen🟢 SAFE — Methadone and Tamoxifen can be taken together safely.
Methadone + Tamsulosin🟢 SAFE — Tamsulosin and Methadone can be taken together safely.
Methadone + Taurine🟢 SAFE — Taurine and Methadone can be taken together safely.
Methadone + Tea Tree OilTea Tree Oil and Methadone — No Known Interaction
Methadone + Tedizolid🟢 SAFE — Methadone and Tedizolid can be taken together safely.
Methadone + Telmisartan🟢 SAFE — Telmisartan and Methadone can be taken together safely.
Methadone + Terazosin🟢 SAFE — Methadone and Terazosin can be taken together safely.
Methadone + Testosterone🟢 SAFE — Testosterone and Methadone can be taken together safely.
Methadone + Tetracycline🟢 SAFE — Methadone and Tetracycline can be taken together safely.
Methadone + Theophylline🟢 SAFE — Methadone and Theophylline can be taken together safely.
Methadone + TianeptineTianeptine and Methadone — No Known Interaction
Methadone + Tiotropium🟢 SAFE — Methadone and Tiotropium can be taken together safely.
Methadone + Tofacitinib🟢 SAFE — Methadone and Tofacitinib can be taken together safely.
Methadone + Tongkat Ali🟢 SAFE — Tongkat Ali and Methadone can be taken together safely.
Methadone + Topiramate🟢 SAFE — Topiramate and Methadone can be taken together safely.
Methadone + Tramadol🟢 SAFE — Tramadol and Methadone can be taken together safely.
Methadone + Trazodone🟢 SAFE — Trazodone and Methadone can be taken together safely.
Methadone + Tribulus Terrestris🟢 SAFE — Tribulus Terrestris and Methadone can be taken together safely.
Methadone + Trimethoprim-Sulfamethoxazole🟢 SAFE — Trimethoprim-Sulfamethoxazole and Methadone can be taken together safely.
Methadone + Triphala🟢 SAFE — Triphala and Methadone can be taken together safely.
Methadone + TurkesteroneTurkesterone and Methadone — No Known Interaction
Methadone + Turkey Tail🟢 SAFE — Turkey Tail and Methadone can be taken together safely.
Methadone + Turmeric🟢 SAFE — Turmeric and Methadone can be taken together safely.
Methadone + Turmeric Latte🟢 SAFE — Methadone and Turmeric Latte can be taken together safely.
Methadone + Tyrosine🟢 SAFE — Tyrosine and Methadone can be taken together safely.
Methadone + Urolithin AUrolithin A and Methadone — No Known Interaction
Methadone + Valerian Root🟢 SAFE — Valerian Root and Methadone can be taken together safely.
Methadone + Valproic Acid🟢 SAFE — Methadone and Valproic Acid can be taken together safely.
Methadone + Valsartan🟢 SAFE — Valsartan and Methadone can be taken together safely.
Methadone + Vanadium🟢 SAFE — Methadone and Vanadium can be taken together safely.
Methadone + Vancomycin Oral🟢 SAFE — Methadone and Vancomycin Oral can be taken together safely.
Methadone + Venlafaxine🟢 SAFE — Venlafaxine and Methadone can be taken together safely.
Methadone + Vilazodone🟢 SAFE — Methadone and Vilazodone can be taken together safely.
Methadone + Vitamin A🟢 SAFE — Vitamin A and Methadone can be taken together safely.
Methadone + Vitamin B1🟢 SAFE — Methadone and Vitamin B1 can be taken together safely.
Methadone + Vitamin B12🟢 SAFE — Vitamin B12 and Methadone can be taken together safely.
Methadone + Vitamin B2🟢 SAFE — Methadone and Vitamin B2 can be taken together safely.
Methadone + Vitamin B3🟢 SAFE — Methadone and Vitamin B3 can be taken together safely.
Methadone + Vitamin B5🟢 SAFE — Methadone and Vitamin B5 can be taken together safely.
Methadone + Vitamin B6🟢 SAFE — Vitamin B6 and Methadone can be taken together safely.
Methadone + Vitamin C🟢 SAFE — Vitamin C and Methadone can be taken together safely.
Methadone + Vitamin D🟢 SAFE — Vitamin D and Methadone can be taken together safely.
Methadone + Vitamin E🟢 SAFE — Methadone and Vitamin E can be taken together safely.
Methadone + Vitamin K2🟢 SAFE — Vitamin K2 and Methadone can be taken together safely.
Methadone + Vitex🟢 SAFE — Vitex and Methadone can be taken together safely.
Methadone + Vortioxetine🟢 SAFE — Methadone and Vortioxetine can be taken together safely.
Methadone + Warfarin🟢 SAFE — Warfarin and Methadone can be taken together safely.
Methadone + Wheat Grass🟢 SAFE — Methadone and Wheat Grass can be taken together safely.
Methadone + Whey Protein🟢 SAFE — Whey Protein and Methadone can be taken together safely.
Methadone + White Tea🟢 SAFE — Methadone and White Tea can be taken together safely.
Methadone + White Willow Bark🟢 SAFE — Methadone and White Willow Bark can be taken together safely.
Methadone + Wild Lettuce🟢 SAFE — Methadone and Wild Lettuce can be taken together safely.
Methadone + Witch Hazel🟢 SAFE — Witch Hazel and Methadone can be taken together safely.
Methadone + WobenzymWobenzym and Methadone — No Known Interaction
Methadone + WormwoodWormwood and Methadone — No Known Interaction
Methadone + Yerba Mate🟢 SAFE — Methadone and Yerba Mate can be taken together safely.
Methadone + Yohimbe🟢 SAFE — Methadone and Yohimbe can be taken together safely.
Methadone + Zeaxanthin🟢 SAFE — Methadone and Zeaxanthin can be taken together safely.
Methadone + Zinc🟢 SAFE — Zinc and Methadone can be taken together safely.
Methadone + Ziprasidone🟢 SAFE — Methadone and Ziprasidone can be taken together safely.
Methadone + ZMA🟢 SAFE — ZMA and Methadone can be taken together safely.
Methadone + Zolpidem🟢 SAFE — Zolpidem and Methadone can be taken together safely.