Leaf & Herb · Other

Pelargonium Sidoides (EPs 7630)

Provisional Strong Scorebotanical

Hermetica Superfood Encyclopedia

Published March 18, 2026Last updated March 18, 2026Methodology · Editorial policy · Report an error

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Pelargonium sidoides is a South African geranium containing active compounds called proanthocyanidins that support respiratory health. The standardized extract EPs 7630 works by enhancing immune cell activity and providing antimicrobial effects against respiratory pathogens.

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Screened PMID Records

Reported Benefits

Pending

Synergy Review

At a Glance

CategoryLeaf & Herb

GroupOther

Public Score StatusProvisional Strong

Primary KeywordPelargonium sidoides benefits

Pelargonium Sidoides (EPs 7630) — botanical close-up

Reported Benefits (Provisional)

Enhances respiratory health by alleviating symptoms of bronchitis and colds

This provides relief from congestion and improves breathing. - Possesses antimicrobial properties that combat bacteria and viruses. This helps in reducing the duration and severity of respiratory infections. - Supports immune function by stimulating the production of immune cells. This strengthens the body's defense mechanisms against pathogens. - Contains anti-inflammatory compounds that reduce inflammation in the respiratory tract. This can alleviate symptoms of conditions like asthma and bronchitis. - May improve overall lung function by enhancing oxygen uptake. This supports better respiratory health and endurance. - Exhibits antioxidant properties that protect respiratory tissues from oxidative damage. This supports long-term respiratory health. - Supports throat health by soothing irritation and reducing cough. This provides symptomatic relief during respiratory infections.

Origin & History

Pelargonium Sidoides (EPs 7630) — origin

Natural habitat

Pelargonium Sidoides, also known as EPs 7630, is a plant native to South Africa. The roots are harvested and processed to create an extract rich in polyphenols and coumarins.

“Used traditionally by South African tribes for respiratory ailments and infections. Gained popularity in Europe for its therapeutic benefits in the 19th century.”Traditional Medicine

Research Narrative (Provisional)

Clinical trials, including RCTs, have shown its effectiveness in treating acute bronchitis and reducing the severity of cold symptoms. Studies support its role in enhancing respiratory health.

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

- Contains umckalin, a key coumarin compound. - Rich in polyphenolic compounds. - Provides essential oils with therapeutic properties.

Reported Mechanism (Provisional)

Mechanism of Action

EPs 7630 contains proanthocyanidins and other phenolic compounds that stimulate macrophage activity and enhance interferon-beta production. These compounds inhibit bacterial adhesion to respiratory epithelial cells and demonstrate direct antimicrobial activity against Streptococcus pyogenes and other respiratory pathogens. The extract also modulates cytokine production, reducing inflammatory responses while supporting immune function.

Clinical Narrative (Provisional)

Multiple randomized controlled trials involving over 2,000 participants demonstrate EPs 7630's efficacy for acute bronchitis and common cold symptoms. Studies show significant reduction in symptom severity scores (typically 40-50% improvement) and shortened illness duration by 2-3 days compared to placebo. Meta-analyses confirm moderate to strong evidence for respiratory tract infection treatment. Most trials used standardized doses of 30-60mg daily for 7-10 days.

Also Known As

Pelargonium sidoidesEPs 7630South African geraniumAfrican potatoUmckaloaboKalwerbossieRabassamBlack geranium

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.

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