
Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Nu Zhen Zi (Ligustrum lucidum) contains oleanolic acid and ligustroside that support liver detoxification and immune function. The fruit modulates hepatic enzymes and enhances T-lymphocyte activity through antioxidant pathways.

Reported Benefits (Provisional)
Origin & History

Nu Zhen Zi is the fruit of the Ligustrum lucidum tree, native to China. The fruits are harvested and dried for use in traditional remedies.
Research Narrative (Provisional)
Preliminary studies suggest Nu Zhen Zi may have immune-boosting and antioxidant properties, but more research is needed to confirm these effects.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
Nu Zhen Zi (Ligustrum lucidum) berries contain a complex array of bioactive compounds rather than significant macronutrient content. Key bioactive constituents include: Oleanolic acid (primary triterpenoid, approximately 0.5-1.2% dry weight), Ursolic acid (co-occurring triterpenoid, ~0.3-0.8% dry weight), and Oleuropein (secoiridoid glycoside, ~1.0-2.5% dry weight). The signature compound Specnuezhenide (a phenylethanoid glycoside) is present at approximately 0.5-1.5% dry weight and serves as the primary quality marker in pharmacopeial standards. Ligustroside and nuzhenide are additional secoiridoid glycosides present at 0.2-0.8% dry weight. Polysaccharides (primarily glucose and galactose polymers) constitute approximately 8-15% dry weight and are considered key immunomodulatory components with moderate bioavailability. Flavonoids including luteolin and apigenin glycosides are present at ~0.1-0.4% dry weight. Salidroside (tyrosol glucoside) is detected at ~0.05-0.2% dry weight. Regarding micronutrients: zinc (~2.1 mg/100g dry weight), manganese (~1.8 mg/100g), and potassium (~320 mg/100g) are the most notable minerals. Crude fiber content is approximately 18-22% dry weight. Protein content is modest at ~4-6% dry weight. Bioavailability notes: Oleanolic acid has limited oral bioavailability (~2-3%) due to poor aqueous solubility; processing as decoction or ethanol extract significantly improves extraction of glycosides; wine-processing (jiu zhi) traditional preparation increases absorption of certain triterpenes by approximately 30-40% based on comparative studies.
Reported Mechanism (Provisional)
Oleanolic acid in Nu Zhen Zi activates hepatic phase II detoxification enzymes including glutathione S-transferase and UDP-glucuronosyltransferase. Ligustroside enhances immune function by increasing T-lymphocyte proliferation and natural killer cell activity. The triterpenes also upregulate antioxidant enzymes like superoxide dismutase and catalase.
Clinical Narrative (Provisional)
Human studies on Nu Zhen Zi are limited, with most research conducted in animal models. A small clinical trial (n=60) showed 6.8g daily improved liver enzyme markers in hepatitis B patients over 8 weeks. Animal studies demonstrate immune enhancement with increased lymphocyte counts at 200-400mg/kg doses. More robust human clinical trials are needed to establish definitive therapeutic benefits and optimal dosing.
Also Known As
Research updates — and 25% off your first order
Join our list for source-aware wellness education, review-state updates, and product news — and unlock 25% off your first Hermetica order. Educational content is not medical advice. No spam, unsubscribe anytime.







