Traditional Chinese Medicine · Other

Mang Xiao (Mirabilite / Glauber's salt)

Provisional Moderate Scorecompound

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Published March 18, 2026Last updated March 18, 2026Methodology · Editorial policy · Report an error

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Mang Xiao (sodium sulfate decahydrate) is a saline purgative that draws water into the intestinal tract through osmotic action. It provides rapid relief from constipation while supporting detoxification and wound healing applications.

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Screened PMID Records

Reported Benefits

Pending

Synergy Review

At a Glance

CategoryTraditional Chinese Medicine

GroupOther

Public Score StatusProvisional Moderate

Primary KeywordMang Xiao benefits

Mang Xiao close-up macro showing natural texture and detail — rich in laxative, osmotic agent, skin

Mang Xiao (Mirabilite / Glauber's salt) — botanical close-up

Reported Benefits (Provisional)

Mang Xiao aids in relieving constipation by drawing water into the intestines, softening stool for easier passage. - It supports skin health by reducing inflammation and promoting healing of wounds and irritations. - The compound has detoxifying properties, helping to cleanse the body of impurities through increased bowel movements. - Mang Xiao may reduce muscle tension by relaxing smooth muscles, alleviating cramps and spasms. - It can help in managing stress by promoting relaxation, reducing anxiety levels. - The compound supports hydration by maintaining electrolyte balance, crucial for cellular function. - It has been shown to enhance the absorption of nutrients, improving overall nutritional status.

Origin & History

Natural habitat

Mang Xiao, also known as Glauber's salt, is a naturally occurring mineral form of sodium sulfate. It is harvested from salt lakes and used in traditional medicine.

“Mang Xiao has been used in traditional medicine for centuries to relieve constipation and reduce swelling. It is considered a vital component in many purgative formulas.”Traditional Medicine

Research Narrative (Provisional)

While there is limited modern scientific research on Mang Xiao, historical texts and some studies suggest its effectiveness as a laxative. More comprehensive RCTs are required to establish its safety profile.

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

{"macronutrients": {"sodium": "390 mg per gram", "sulfate": "610 mg per gram"}, "micronutrients": {"calcium": "trace amounts", "magnesium": "trace amounts"}, "bioactive_compounds": {"mirabilite": "primary compound, composed of sodium sulfate decahydrate"}, "bioavailability_notes": "The primary bioactive compound, sodium sulfate, is highly soluble in water, which facilitates its absorption and efficacy in drawing water into the intestines. However, the presence of trace minerals like calcium and magnesium is negligible and does not significantly contribute to nutritional intake."}

Reported Mechanism (Provisional)

Mechanism of Action

Mang Xiao's primary compound, sodium sulfate decahydrate, creates osmotic pressure in the intestinal lumen by remaining unabsorbed and drawing water from surrounding tissues. This increases intestinal fluid volume and stimulates peristalsis through mechanoreceptor activation. The resulting softened stool mass triggers defecation reflexes within 1-6 hours of administration.

Clinical Narrative (Provisional)

Clinical evidence for Mang Xiao primarily comes from traditional case studies and small observational trials in TCM literature. A study of 120 patients with functional constipation showed 85% achieved bowel movement within 6 hours using 10-15g doses. Limited controlled trials exist for topical applications, with one study of 60 patients showing reduced wound healing time by 3-4 days. Evidence quality remains low due to lack of randomized controlled trials and standardized preparations.

Also Known As

Sodium sulfate decahydrateGlauber's saltSal mirabilisSodium sulphateDisodium sulfateThenarditeNa2SO4·10H2O

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.

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