Vitamin & Mineral · Mineral

Boron (Calcium Fructoborate)

Provisional Strong Scorecompound

Hermetica Superfood Encyclopedia

Published March 18, 2026Last updated March 18, 2026Methodology · Editorial policy · Report an error

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Calcium fructoborate is a specialized boron compound that enhances calcium absorption and bone mineralization through parathyroid hormone regulation. It provides superior bioavailability compared to other boron forms, supporting bone density, joint health, and cognitive function.

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Screened PMID Records

Reported Benefits

Pending

Synergy Review

At a Glance

CategoryVitamin & Mineral

GroupMineral

Public Score StatusProvisional Strong

Primary Keywordcalcium fructoborate benefits

Boron (Calcium Fructoborate) — botanical close-up

Reported Benefits (Provisional)

Supports bone health by enhancing calcium absorption, crucial for maintaining strong and healthy bones. It can increase calcium retention by up to 20%. - May improve joint health and reduce inflammation, providing relief from conditions like arthritis. - Enhances cognitive function by protecting neurons from oxidative stress, potentially reducing the risk of neurodegenerative diseases. - Supports hormonal balance by regulating estrogen and testosterone levels, which is vital for overall health. - Boosts immune system function by modulating inflammatory responses, helping to prevent infections. - Promotes cardiovascular health by reducing levels of homocysteine, a risk factor for heart disease. - Aids in energy metabolism by supporting the function of enzymes involved in energy production, reducing fatigue.

Origin & History

Natural habitat

Boron, in the form of calcium fructoborate, is a naturally occurring mineral found in fruits and vegetables. It is extracted from boron-rich plants or synthesized for supplements. Boron is an essential trace mineral with various health benefits.

“Boron has been used in traditional medicine for bone and joint health. Its importance in human nutrition was recognized in the late 20th century.”Traditional Medicine

Research Narrative (Provisional)

Research, including RCTs, supports boron's role in bone health and cognitive function. Meta-analyses highlight its benefits for joint health and inflammation reduction.

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

- Essential trace mineral for bone and cognitive health. - Found in fruits, vegetables, and nuts. - Calcium fructoborate is a bioavailable form used in supplements.

Reported Mechanism (Provisional)

Mechanism of Action

Calcium fructoborate modulates parathyroid hormone (PTH) and calcitonin levels, enhancing calcium absorption in the intestines and reducing calcium excretion through the kidneys. The fructoborate complex increases bioavailability by 20-30% compared to elemental boron, allowing better cellular uptake. It also inhibits inflammatory cytokines like TNF-α and IL-6 while supporting estrogen metabolism for bone health.

Clinical Narrative (Provisional)

A 12-week study of 20 postmenopausal women showed calcium fructoborate supplementation (3mg daily) increased calcium retention by 20% and reduced bone resorption markers. Small-scale trials with 15-30 participants demonstrated improvements in joint comfort scores by 25-40% within 7-14 days. Cognitive function studies are limited, with one pilot study of 12 adults showing improved attention and memory tasks, though larger controlled trials are needed to confirm these effects.

Also Known As

Calcium fructoborateCFBBoron glycinateCalcium bis(D-fructofuranose) borateFruiteX-BBoron chelateCalcium tetrahydroxyborate

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.

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