
Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Ban Xia Xie Xin Tang is a traditional Chinese herbal formula containing Pinellia ternata, Scutellaria baicalensis, and Coptis chinensis that regulates gastrointestinal function. The formula works through anti-inflammatory compounds like baicalin and berberine that modulate gut microbiota and reduce gastric inflammation.

Reported Benefits (Provisional)
Origin & History

Ban Xia Xie Xin Tang is a traditional Chinese herbal formula designed to harmonize the stomach and eliminate dampness. Originating from the Han dynasty, it is made by decocting a combination of herbs including pinellia and scutellaria.
Research Narrative (Provisional)
Research, including some RCTs, has explored the use of Ban Xia Xie Xin Tang for digestive disorders, with findings suggesting potential benefits in reducing gastric discomfort and improving gut health. Further studies are needed to validate these results.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
Ban Xia Xie Xin Tang is a multi-herb decoction comprising seven herbs, each contributing distinct bioactive compounds. Pinellia ternata (Ban Xia) contains homogentisic acid, ephedrine analogs, and β-sitosterol with demonstrated anti-emetic alkaloids at approximately 0.1–0.3% dry weight. Coptis chinensis (Huang Lian) provides berberine (5–8% dry weight), a highly studied alkaloid with antimicrobial and glucose-regulating properties; berberine bioavailability is notably low (~5%) but enhanced by P-glycoprotein inhibitors present in the formula. Scutellaria baicalensis (Huang Qin) contributes baicalin (10–15% dry weight) and baicalein, flavonoids with anti-inflammatory activity. Zingiber officinale (Gan Jiang/dry ginger) adds gingerols and shogaols (~1–2% dry weight) supporting gastroprokinetic activity. Glycyrrhiza uralensis (Gan Cao) provides glycyrrhizin (~2–4% dry weight) and liquiritin, which modulate cortisol metabolism and offer mucosal protection. Panax ginseng (Ren Shen) contributes ginsenosides Rb1 and Rg1 (~2–3% dry weight), supporting adaptogenic and anti-inflammatory pathways. Ziziphus jujuba (Da Zao) adds polysaccharides (~30–40% dry weight) and triterpenic acids supporting gut mucosal integrity. Macronutrient content is negligible as consumed in decoction form. Mineral content includes trace potassium (~80–120 mg per standard 200 mL serving) and calcium from herb matrices. Fiber is largely absent post-decoction. Bioavailability of berberine and baicalin is synergistically enhanced within the formula due to P-gp inhibition by glycyrrhizin.
Reported Mechanism (Provisional)
The formula's bioactive compounds including baicalin from Scutellaria and berberine from Coptis inhibit pro-inflammatory cytokines like TNF-α and IL-6 in gastric tissues. Gingerols from fresh ginger stimulate gastric motility through 5-HT3 receptor modulation, while glycyrrhizin from licorice protects gastric mucosa by enhancing prostaglandin E2 production. These synergistic actions restore gut microbiota balance and normalize digestive enzyme secretion.
Clinical Narrative (Provisional)
Clinical studies involving 200-400 participants have demonstrated significant improvements in functional dyspepsia symptoms, with 60-75% of patients showing reduced bloating and gastric discomfort after 4-8 weeks of treatment. Randomized controlled trials indicate the formula effectively modulates gut microbiota composition, increasing beneficial Lactobacillus and Bifidobacterium populations. However, most studies are conducted in Asian populations with relatively small sample sizes, and more large-scale Western trials are needed to confirm universal efficacy.
Also Known As
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