Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Bacillus subtilis DE111 is a spore-forming probiotic strain that produces digestive enzymes and antimicrobial compounds to support gut health. It works by colonizing the intestinal tract, enhancing nutrient absorption, and modulating immune responses through direct bacterial communication.
Reported Benefits (Provisional)
Origin & History
Bacillus subtilis DE111 is a soil-based probiotic strain derived from natural soil environments. It is produced through fermentation and is known for its resilience in harsh conditions, making it a stable probiotic option.
Research Narrative (Provisional)
Several clinical trials have demonstrated its efficacy in supporting digestive health and immune function. Studies highlight its stability and resilience as a probiotic.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Produces digestive enzymes that aid in nutrient breakdown. - Contains spores that ensure survival through the digestive tract. - Supports the production of beneficial short-chain fatty acids.
Reported Mechanism (Provisional)
Bacillus subtilis DE111 produces proteases, amylases, and lipases that enhance protein, carbohydrate, and fat digestion. The strain synthesizes surfactin and other lipopeptides that exhibit antimicrobial properties against pathogenic bacteria. It modulates immune function by stimulating Toll-like receptors and promoting regulatory T-cell activity in gut-associated lymphoid tissue.
Clinical Narrative (Provisional)
Human studies on Bacillus subtilis DE111 include a 2017 randomized controlled trial with 45 participants showing significant improvements in digestive comfort and bowel regularity after 30 days of supplementation. A 2019 study with 60 subjects demonstrated enhanced immune markers including increased secretory IgA levels. Most research involves small sample sizes of 30-60 participants over 4-8 week periods, indicating promising but preliminary evidence for digestive and immune benefits.
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