MODERATE — Monitor Closely
🟡 MODERATE — Alcohol worsens Fluvoxamine side effects.
Evidence level: STRONG
Alcohol and fluvoxamine increase each other's side effects. Fluvoxamine may alter how you process alcohol.
Additive CNS depression. Fluvoxamine potently inhibits CYP1A2/CYP2C19, potentially altering alcohol metabolism.
Avoid or strictly limit alcohol while taking fluvoxamine.
Take Fluvoxamine at the same time daily. Most SSRIs can be taken with or without food, though food may reduce GI side effects. Alcohol — if it's high in tyramine (aged cheese, cured meats, fermented foods), this is mainly a concern with MAOIs, not SSRIs. SSRIs are generally food-flexible.
OCD patients, elderly
Increased nausea, drowsiness, impaired judgment
Discuss alcohol avoidance with your psychiatrist
Discuss this combination with your prescriber. They may adjust timing, dosing, or switch to an alternative with fewer interaction risks. Never stop an antidepressant abruptly — taper under medical guidance.
Alcohol and fluvoxamine increase each other's side effects. Fluvoxamine may alter how you process alcohol.
Take Fluvoxamine at the same time daily. Most SSRIs can be taken with or without food, though food may reduce GI side effects. Alcohol — if it's high in tyramine (aged cheese, cured meats, fermented foods), this is mainly a concern with MAOIs, not SSRIs. SSRIs are generally food-flexible.
Increased nausea, drowsiness, impaired judgment
Discuss this combination with your prescriber. They may adjust timing, dosing, or switch to an alternative with fewer interaction risks. Never stop an antidepressant abruptly — taper under medical guidance.
Discuss alcohol avoidance with your psychiatrist
Or browse the full interaction database (121,000+ pairs).