# Rangoon Creeper Fruit **Canonical URL:** https://ingredients.hermeticasuperfoods.com/ingredients/rangoon-creeper-fruit **Data Source:** Hermetica Superfoods Ingredient Encyclopedia **Updated:** 2026-03-15 **Evidence Score:** 6 / 10 **Category:** Fruit **Also Known As:** Combretum indicum, Quisqualis indica, Rangoon Creeper ## Overview Rangoon Creeper Fruit contains an alkaloid with anthelmintic properties and neuroexcitatory amino acids, alongside flavonoids and polyphenols. Its mechanism involves antioxidant and [immunomodulatory](/ingredients/condition/immune-support) activities, contributing to its traditional use in [oxidative stress](/ingredients/condition/antioxidant)-related conditions. ## Health Benefits - Supports gut health by promoting a balanced [microbiome](/ingredients/condition/gut-health) and aiding in parasite removal. - Enhances detoxification processes by supporting [liver function](/ingredients/condition/detox) and systemic cleansing. - Reduces [oxidative stress](/ingredients/condition/antioxidant) through its rich content of flavonoids and polyphenols. - Promotes metabolic balance by influencing glucose and lipid [metabolism](/ingredients/condition/weight-management). ## Mechanism of Action The fruit's anthelmintic properties are attributed to an identified alkaloid, targeting and aiding in the expulsion of parasites. Its antioxidant and [immunomodulatory](/ingredients/condition/immune-support) activities are largely mediated by its content of flavonoids and polyphenols, which help neutralize [free radical](/ingredients/condition/antioxidant)s and modulate immune responses. Additionally, specific neuroexcitatory amino acids contribute to its biological effects, though their precise role in health benefits needs further elucidation. ## Clinical Summary Preliminary research, primarily in vitro studies and observations based on traditional use, suggests Rangoon Creeper Fruit's potential in supporting gut health, enhancing detoxification, and reducing [oxidative stress](/ingredients/condition/antioxidant). These findings indicate promising avenues for its application in parasitic removal and overall systemic cleansing. However, robust human clinical trials, including randomized controlled trials with adequate sample sizes, are still required to fully substantiate these preliminary results and establish definitive efficacy and safety profiles. ## Nutritional Profile - [Prebiotic](/ingredients/condition/gut-health) fiber - Potassium, Magnesium, Iron - Flavonoids, Tannins, Saponins, Quercetin, Bioactive alkaloids, Polyphenols ## Dosage & Preparation - Traditionally consumed fresh or brewed in decoctions for digestive cleansing. - Modern forms include extracts or incorporated into functional products. - Recommended dosage is 500–1000 mg of extract daily or 1–2 servings in functional products. ## Safety & Drug Interactions Information regarding the specific safety profile, potential side effects, and drug interactions of Rangoon Creeper Fruit is not extensively documented in the available preliminary research. Therefore, individuals should exercise caution and consult a healthcare professional before use, especially if pregnant, nursing, or taking other medications. Specific contraindications have not been identified in the provided sources, necessitating further investigation into its comprehensive safety data. ## Scientific Research Preliminary research, including in vitro and traditional use observations, suggests Rangoon Creeper Fruit's potential in supporting gut health, detoxification, and [oxidative stress](/ingredients/condition/antioxidant) reduction. While promising, further human clinical trials, particularly randomized controlled trials, are needed to fully substantiate these benefits. The existing evidence supports its traditional applications in wellness. ## Historical & Cultural Context Rangoon Creeper Fruit has been traditionally used in Ayurvedic and Southeast Asian medicine for its profound effects on digestive cleansing, parasite removal, and promoting gut resilience. Its historical application underscores its role in maintaining internal purity and vitality. This fruit is a cornerstone in traditional practices focused on gut health. ## Synergistic Combinations Role: Polyphenol/[antioxidant](/ingredients/condition/antioxidant) base Intention: Detox & Liver | Energy & [Metabolism](/ingredients/condition/weight-management) Primary Pairings: - Turmeric (Curcuma longa) - Camu Camu - Ginger (Zingiber officinale) - Maca Root (Lepidium meyenii) ## Frequently Asked Questions ### What are the primary bioactive compounds found in Rangoon Creeper Fruit? Rangoon Creeper Fruit contains a diverse array of bioactive compounds, including fatty acids like linoleic and oleic acids, and an alkaloid known for its anthelmintic properties. It also features neuroexcitatory amino acids and sugary-acidic components similar to levulose and cathartic acid. ### How does Rangoon Creeper Fruit support gut health? The fruit supports gut health primarily through its anthelmintic (antiparasitic) alkaloid, which aids in the removal of parasites, thereby promoting a balanced gut microbiome. Its traditional use points to its role in general gut cleansing and wellness. ### What is the primary mechanism of action for Rangoon Creeper Fruit's benefits? The main mechanism of action involves its antioxidant and immunomodulatory activities, largely attributed to the presence of flavonoids and polyphenols. These compounds help to reduce oxidative stress and modulate the body's immune responses. ### Is there strong scientific evidence for Rangoon Creeper Fruit's health benefits? Preliminary research, including in vitro studies and observations based on traditional use, suggests potential benefits in gut health, detoxification, and oxidative stress reduction. However, robust human clinical trials, such as randomized controlled trials, are still needed to fully establish its efficacy and safety. ### Are there any known side effects or drug interactions for Rangoon Creeper Fruit? The provided research does not extensively detail the specific safety profile, potential side effects, or drug interactions of Rangoon Creeper Fruit. It is advisable to consult a healthcare professional before use, especially for pregnant or nursing individuals or those on medication, due to limited comprehensive safety data. ### What foods naturally contain Rangoon Creeper Fruit, and can I get its benefits from diet alone? Rangoon Creeper Fruit (Quisqualis indica) is primarily grown in tropical regions of Asia and is not commonly available in Western grocery stores, making dietary intake limited for most populations. The fruit is traditionally consumed fresh or dried in Southeast Asian cuisines, but achieving therapeutic levels of its bioactive compounds through food sources alone may be difficult outside these regions. Supplementation typically provides more concentrated and consistent doses of the fruit's flavonoids and polyphenols compared to occasional dietary consumption. ### Who benefits most from Rangoon Creeper Fruit supplementation, and who should avoid it? Rangoon Creeper Fruit supplementation may be most beneficial for individuals with compromised gut health, parasitic concerns, or those seeking natural detoxification support, particularly in tropical or subtropical regions where parasitic exposure is more common. Pregnant and nursing women should consult healthcare providers before use due to limited safety data in these populations, and individuals with severe liver or kidney disease should exercise caution. Those taking antiparasitic medications or with known allergies to Combretaceae family plants should avoid supplementation without professional guidance. ### What is the most effective form of Rangoon Creeper Fruit supplement, and how does the form affect its benefits? Rangoon Creeper Fruit is available in dried whole fruit, powder, extract, and capsule forms, with standardized extracts typically offering higher concentrations of bioactive flavonoids and polyphenols compared to whole dried fruit. The extraction process can significantly enhance bioavailability of the fruit's active compounds, making extracts potentially more efficient for supporting detoxification and metabolic balance. Capsule and powder forms generally provide better consistency in dosing and easier integration into daily supplement routines compared to whole dried fruit. ## References Research links: https://www.ncbi.nlm.nih.gov/search/all/?term=Rangoon+Creeper+Fruit; https://fdc.nal.usda.gov/fdc-app.html#/search?query=Rangoon+Creeper+Fruit | Studies: https://pubmed.ncbi.nlm.nih.gov/?term=Rangoon+Creeper+Fruit --- *Source: Hermetica Superfoods Ingredient Encyclopedia — https://ingredients.hermeticasuperfoods.com* *License: CC BY-NC-SA 4.0 — Attribution required. Commercial use: admin@hermeticasuperfoods.com*