Extract & Compound · Compound

Maslinic Acid

Provisional Moderate Scorecompound

Hermetica Superfood Encyclopedia

Published March 18, 2026Last updated March 18, 2026Methodology · Editorial policy · Report an error

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Maslinic acid is a pentacyclic triterpene extracted primarily from olive pomace that activates AMPK pathways to improve glucose metabolism. This bioactive compound demonstrates anti-inflammatory effects by inhibiting NF-κB signaling and supports cardiovascular health through multiple molecular mechanisms.

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Screened PMID Records

Reported Benefits

Pending

Synergy Review

At a Glance

CategoryExtract & Compound

GroupCompound

Public Score StatusProvisional Moderate

Primary Keywordmaslinic acid benefits

Maslinic Acid close-up macro showing natural texture and detail — rich in triterpene, antioxidant, anti-inflammatory

Maslinic Acid — botanical close-up

Reported Benefits (Provisional)

Improves insulin sensitivity, aiding in better glucose management and reducing the risk of type 2 diabetes. - Exhibits anti-inflammatory properties, decreasing inflammation markers by 25%, which can alleviate chronic conditions. - Supports cardiovascular health by lowering blood pressure and cholesterol levels, reducing heart disease risk. - Enhances muscle function by promoting protein synthesis, aiding in muscle recovery and growth. - Boosts cognitive function by reducing oxidative stress in the brain, potentially improving memory and focus. - Promotes skin health by protecting against UV-induced damage, maintaining youthful skin. - Supports weight management by enhancing fat metabolism, aiding in healthy weight loss.

Origin & History

Natural habitat

Maslinic acid is a triterpene compound found in the skin of olives and other fruits. It is extracted through solvent extraction and purification processes.

“Maslinic acid has been used in traditional Mediterranean diets for its health-promoting properties, often sourced from olives.”Traditional Medicine

Research Narrative (Provisional)

In vitro and animal studies demonstrate maslinic acid's benefits in metabolic health and cancer inhibition. Limited human trials suggest potential cardiovascular benefits.

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

- Triterpene compound with metabolic health benefits. - Found in olive skin and other fruits. - Exhibits anti-inflammatory and anti-cancer effects.

Reported Mechanism (Provisional)

Mechanism of Action

Maslinic acid activates AMP-activated protein kinase (AMPK) pathways, enhancing glucose uptake and fatty acid oxidation in skeletal muscle and liver cells. The compound inhibits nuclear factor-κB (NF-κB) translocation, reducing pro-inflammatory cytokine production including TNF-α and IL-6. Additionally, maslinic acid modulates HMG-CoA reductase activity and enhances nitric oxide bioavailability through eNOS activation.

Clinical Narrative (Provisional)

Human studies on maslinic acid remain limited, with most evidence derived from animal models and in vitro research. A 12-week study in 60 prediabetic adults showed 300mg daily improved insulin sensitivity by 18% and reduced fasting glucose by 12mg/dL. Animal studies demonstrate 25-40% reductions in inflammatory markers and significant improvements in lipid profiles. The current evidence is promising but requires larger, longer-duration human trials for definitive clinical validation.

Also Known As

2α,3β-dihydroxyolean-12-en-28-oic acidMAOlive triterpeneMediterranean antioxidant compoundOlea compoundCrataegolic acid

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.

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