Branded Ingredient · Other

Magtein (Magnesium L-Threonate)

Provisional Strong Scorecompound

Hermetica Superfood Encyclopedia

Published March 18, 2026Last updated March 18, 2026Methodology · Editorial policy · Report an error

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Magtein (Magnesium L-Threonate) is a patented magnesium compound specifically designed to cross the blood-brain barrier and increase brain magnesium levels by 15%. It enhances synaptic plasticity and neuroplasticity through NMDA receptor modulation, supporting memory formation and cognitive function.

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Screened PMID Records

Reported Benefits

Pending

Synergy Review

At a Glance

CategoryBranded Ingredient

GroupOther

Public Score StatusProvisional Strong

Primary KeywordMagtein benefits

Magtein (Magnesium L-Threonate) — botanical close-up

Reported Benefits (Provisional)

Enhances cognitive function

Magtein is the only magnesium form shown to cross the blood-brain barrier, improving memory and learning. This supports brain health and cognitive longevity. - Reduces anxiety and stress: By increasing magnesium levels in the brain, Magtein helps regulate neurotransmitters, reducing anxiety symptoms. This promotes a calm and balanced mood. - Supports sleep quality: Magnesium is essential for the production of melatonin, the sleep hormone, enhancing sleep quality and duration. This ensures restful nights and rejuvenated mornings. - Boosts brain plasticity: Magtein increases synaptic density, supporting brain plasticity and adaptability. This is crucial for learning and memory retention. - Improves attention and focus: By modulating neural pathways, Magtein enhances attention span and focus. This is vital for productivity and mental clarity. - Supports neurological health: Magtein helps protect against neurodegenerative diseases by reducing oxidative stress in the brain. This supports long-term brain health. - Enhances energy metabolism: Magnesium is involved in ATP production, the energy currency of cells, boosting overall energy levels. This is essential for maintaining an active lifestyle.

Origin & History

Magtein (Magnesium L-Threonate) — origin

Natural habitat

Magtein is a patented form of magnesium L-threonate, developed to enhance magnesium delivery to the brain. It is produced through a proprietary process that increases its bioavailability.

“Magnesium has been used traditionally for its calming effects, but Magtein specifically targets brain health, a modern innovation in magnesium supplementation.”Traditional Medicine

Research Narrative (Provisional)

Research, including randomized controlled trials, suggests Magtein effectively crosses the blood-brain barrier, improving cognitive function and memory in animal and human studies.

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

{"macronutrients": {"protein": "0g", "fat": "0g", "carbohydrates": "0g"}, "micronutrients": {"magnesium": "144mg per 2g serving", "calcium": "0mg", "iron": "0mg"}, "bioactive_compounds": {"magnesium L-threonate": "2000mg per serving"}, "bioavailability_notes": "Magnesium L-threonate is specifically formulated to enhance magnesium absorption into the brain, crossing the blood-brain barrier more effectively than other forms of magnesium."}

Reported Mechanism (Provisional)

Mechanism of Action

Magtein increases brain magnesium concentrations through enhanced transport across the blood-brain barrier via the threonate moiety. Elevated brain magnesium enhances NMDA receptor function and synaptic plasticity, promoting long-term potentiation (LTP) essential for memory formation. The compound specifically targets hippocampal neurons, increasing synaptic density and improving communication between brain cells.

Clinical Narrative (Provisional)

Human clinical trials demonstrate that 2 grams daily of Magtein for 12 weeks improved memory test scores by 13.1% in adults aged 50-70. Animal studies show 15% increases in brain magnesium levels and enhanced performance in memory tasks. However, human research is limited to small-scale studies with fewer than 50 participants. More large-scale, long-term clinical trials are needed to confirm cognitive benefits across diverse populations.

Also Known As

Magnesium bis(L-threoninate)Mg-L-threonateL-Threonic acid magnesium saltMagnesium L-threonateBrain magnesiumCognitive magnesiumNeuro-magnesium

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.

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