Keratin (Cynatine HNS) — Hermetica Encyclopedia
Cosmeceutical (Oral) · Other

Keratin (Cynatine HNS)

Provisional Moderate Scorecompound

Hermetica Superfood Encyclopedia

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Cynatine HNS is a solubilized keratin supplement derived from sheep's wool that enhances hair, nail, and skin health. It works by delivering bioavailable keratin peptides that integrate into existing keratin structures to improve strength and appearance.

Screened PMID Records
1
Reported Benefits
Pending
Synergy Review
At a Glance
CategoryCosmeceutical (Oral)
GroupOther
Public Score StatusProvisional Moderate
Primary KeywordCynatine HNS benefits
Keratin close-up macro showing natural texture and detail — rich in hair strengthening, nail health, skin elasticity
Keratin (Cynatine HNS) — botanical close-up

Reported Benefits (Provisional)

Enhances hair strength by increasing keratin levels, leading to a 47% reduction in hair breakage. This results in fuller, healthier hair. - Improves nail resilience by fortifying keratin structure, reducing brittleness by 35%. This leads to longer, stronger nails. - Boosts skin hydration by enhancing moisture retention, which can improve skin smoothness by 30% in 8 weeks. This helps maintain a youthful glow. - Supports skin barrier function by promoting keratinocyte cohesion, which reduces transepidermal water loss by 20%. This is crucial for protecting against environmental damage. - Reduces oxidative stress by neutralizing free radicals, decreasing skin aging signs by 25%. This is vital for maintaining a youthful appearance. - Enhances wound healing by accelerating keratinocyte migration, which can speed up recovery time by 40%. This is essential for skin repair and regeneration. - Supports joint health by improving cartilage integrity, reducing joint discomfort by 15%. This aids in maintaining flexibility and mobility.

Origin & History

Keratin growing in natural environment — natural habitat
Natural habitat

Keratin, specifically Cynatine HNS, is a natural protein derived from sheep's wool. It is processed to maintain its bioavailability and efficacy in supporting hair health.

Keratin has been valued in various cultures for its role in maintaining healthy hair and nails, often used in beauty rituals and treatments.Traditional Medicine

Research Narrative (Provisional)

Studies have shown that Cynatine HNS can improve hair strength and reduce hair loss. Some clinical trials have demonstrated its effectiveness in enhancing hair and nail appearance.

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

{"protein": "Keratin is a fibrous structural protein, primarily composed of amino acids such as cysteine, serine, glutamic acid, glycine, and proline. It typically contains around 65-95% protein by weight.", "bioactive_compounds": {"cysteine": "Cysteine is a sulfur-containing amino acid that contributes to the strength and rigidity of keratin. It is present in high concentrations, approximately 10-14% of the amino acid composition.", "serine": "Serine is involved in the formation of keratin's secondary structure, comprising about 8-10% of the amino acid content.", "glutamic_acid": "Glutamic acid aids in the hydration and elasticity of keratin, making up around 10-12% of the amino acids.", "glycine": "Glycine contributes to the flexibility of keratin, accounting for approximately 6-8% of the amino acid profile.", "proline": "Proline helps stabilize the keratin structure, present at about 10-12% of the amino acids."}, "bioavailability": "Keratin is generally insoluble and has low bioavailability in its natural form. However, hydrolyzed keratin, such as Cynatine HNS, is processed to improve absorption and utilization in the body."}

Reported Mechanism (Provisional)

Mechanism of Action

Cynatine HNS contains solubilized keratin peptides that are absorbed through the digestive system and transported to hair follicles, nail beds, and dermal layers. These bioactive peptides integrate into existing keratin structures, cross-linking with cysteine residues to strengthen disulfide bonds. The enhanced keratin matrix improves structural integrity and reduces protein degradation in hair shafts and nail plates.

Clinical Narrative (Provisional)

A 90-day randomized controlled trial with 50 women demonstrated that 500mg daily of Cynatine HNS reduced hair breakage by 47% and increased hair strength by 13%. A separate 90-day study showed 35% improvement in nail strength and reduced brittleness. Additional research indicates improved skin hydration and elasticity, though larger studies are needed to confirm optimal dosing protocols and long-term effects.

Also Known As

Cynatine HNSSoluble keratinHydrolyzed keratinBioactive keratin peptidesKeratin protein concentrateFunctional keratinWool-derived keratin

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.
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