Fruit

Japanese Raisin Tree Fruit

Provisional Moderate Scorebotanical

Hermetica Superfood Encyclopedia

Published March 18, 2026Last updated March 18, 2026Methodology · Editorial policy · Report an error

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Japanese raisin tree fruit contains dihydromyricetin (DHM), a flavonoid that enhances liver detoxification by modulating GABA receptors and accelerating alcohol metabolism. DHM supports hepatic function through aldehyde dehydrogenase activation and reduced oxidative stress pathways.

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Screened PMID Records

Reported Benefits

Pending

Synergy Review

At a Glance

CategoryFruit

GroupFruit

Public Score StatusProvisional Moderate

Primary KeywordJapanese raisin tree fruit benefits

Japanese Raisin Tree Fruit close-up macro showing natural texture and detail — rich in hepatoprotective, antioxidant, detoxifying

Japanese Raisin Tree Fruit — botanical close-up

Reported Benefits (Provisional)

Supports liver detoxification by accelerating the breakdown of toxins and reducing oxidative stress.

Enhances metabolic function by stabilizing blood sugar levels and improving lipid metabolism.

Strengthens immune resilience with antimicrobial and anti-inflammatory bioactives.

Promotes digestive wellness by soothing gastrointestinal inflammation and supporting gut microbiota.

Provides neuroprotective effects by reducing cognitive decline and oxidative damage.

Supports skin hydration and collagen production for anti-aging benefits

Additional benefits include cardiovascular support, adrenal health, and cellular regeneration.

Origin & History

Natural habitat

Native to East Asia, particularly Japan, Korea, and China, thriving in temperate and subtropical forests with well-drained, nutrient-rich soils. Traditionally revered in Traditional Chinese Medicine (TCM) and Japanese Kampo medicine for its potent liver-detoxifying, neuroprotective, and metabolic-enhancing properties.

“Japanese Raisin Tree Fruit carries a meaningful place in traditional wellness systems. Native to East Asia, particularly Japan, Korea, and China, thriving in temperate and subtropical forests with well-drained, nutrient-rich soils. Historically prized for its capacity to support liver detoxification by accelerating the breakdown of toxins and reducing oxidative stress.”Traditional Medicine

Research Narrative (Provisional)

Respected for centuries in TCM and Kampo for liver cleansing and neurological support. Research on Japanese Raisin Tree Fruit has evaluated its phytochemical composition, including polyphenol, flavonoid, and carotenoid content. Antioxidant capacity has been measured using ORAC and DPPH assays. Nutritional analyses have characterized vitamin, mineral, and fiber profiles. Preclinical studies suggest anti-inflammatory and cardioprotective potential. Further clinical investigation is needed to validate traditional health applications.

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

- Dihydromyricetin (DHM) & Flavonoids: Aid liver detoxification and enhance cognitive clarity. - Polyphenols & Terpenoids: Deliver anti-inflammatory and rejuvenating effects. - Saponins & Tannins: Support digestive health and lower cholesterol. - Vitamins A, C & E: Strengthen immunity, boost collagen, and combat oxidative stress. - Potassium, Magnesium & Calcium: Aid nerve, bone, and electrolyte function. - Chlorogenic Acid & Phytosterols: Promote detoxification and metabolic balance.

Reported Mechanism (Provisional)

Mechanism of Action

Dihydromyricetin (DHM) enhances alcohol dehydrogenase and aldehyde dehydrogenase activity, accelerating ethanol metabolism and reducing acetaldehyde accumulation. DHM modulates GABA-A receptors to counteract alcohol's sedative effects while activating Nrf2 pathways for antioxidant enzyme production. The compound also inhibits inflammatory cytokines IL-6 and TNF-α while supporting glucose transporter GLUT4 translocation for improved metabolic function.

Clinical Narrative (Provisional)

Human studies on DHM are limited, with most evidence from animal models and in vitro research. A small pilot study (n=32) showed 30% faster alcohol clearance with 300mg DHM supplementation. Rodent studies demonstrate significant hepatoprotective effects at 50-100mg/kg doses, with 40-60% reduction in liver enzyme markers. Current clinical evidence is promising but requires larger randomized controlled trials for definitive therapeutic claims.

Also Known As

Hovenia dulcisOriental Raisin TreeKenponaishiZhi Ju ZiKorean Raisin TreeCandy TreeHoney Tree

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.

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