
Hermetica Superfood Encyclopedia
Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.
Review flags: AWAITING_SEMANTIC_VALIDATION
Iranian Lime Butter, primarily leveraging lime peel extracts, offers robust antioxidant and anti-inflammatory support through its rich content of phenolic compounds. Key bioactives like naringin and hesperidin specifically inhibit macrophage migration inhibitory factor (MIF) tautomerase activity, contributing to its cellular and immune benefits.

Reported Benefits (Provisional)
Origin & History

Iranian Lime Butter is a luxurious, nutrient-rich ingredient derived from the zest and juice of premium limes (Citrus aurantifolia) grown in the lush orchards of Iran. It is crafted by blending concentrated lime extract with high-quality, grass-fed butter or plant-based alternatives. This unique preparation offers a tangy flavor and vibrant aroma, providing a bioavailable source of beneficial compounds for functional nutrition.
Research Narrative (Provisional)
Preliminary studies confirm the antioxidant properties of lime, its benefits for digestive health, and its positive impact on inflammation, primarily attributed to flavonoids. Further research is needed to specifically evaluate the bioavailability and efficacy of Iranian Lime Butter as a distinct functional food.
Preparation & Dosage
Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.
Nutritional Profile
- Healthy Fats: Supports brain function, energy production, and nutrient absorption. - Vitamin C: Potent antioxidant that boosts immunity and supports skin health. - Flavonoids: Provide anti-inflammatory and antioxidant properties, protecting cells from damage. - Trace Minerals: Small amounts of calcium, potassium, and magnesium support overall physiological functions.
Reported Mechanism (Provisional)
The primary bioactive compounds, such as phenolic compounds like naringin and hesperidin found in lime peel extracts, inhibit macrophage migration inhibitory factor (MIF) tautomerase activity with an IC50 of 70.42 mg/L. This inhibition, occurring reversibly at the enzyme's binding pocket, disrupts inflammatory pathways. Additionally, Vitamin C and other flavonoids provide broad-spectrum antioxidant support by neutralizing free radicals and promoting cellular repair.
Clinical Narrative (Provisional)
Preliminary *in vitro* and *animal* studies have confirmed the antioxidant and anti-inflammatory properties of lime extracts, attributing benefits to compounds like naringin and hesperidin, which inhibit MIF tautomerase. While existing research supports improved digestive health and general anti-inflammatory effects from lime components, specific clinical trials on Iranian Lime Butter as a distinct functional ingredient are lacking. Further human studies are needed to evaluate its bioavailability, optimal dosage, and efficacy, particularly for cholesterol-lowering effects.
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