Ellagic Acid from Strawberries — Hermetica Encyclopedia
Fruit · Compound

Ellagic Acid from Strawberries

Provisional Moderate ScoreCompound

Hermetica Superfood Encyclopedia

Evidence review status: unreviewed

Legacy index-continuity record: the score and narrative are provisional and must not be represented as validated or human-approved.

Review flags: AWAITING_SEMANTIC_VALIDATION

Provisional Summary

Ellagic acid is a key polyphenolic compound found in strawberries, known for its potent antioxidant, anti-inflammatory, and anti-carcinogenic properties. It primarily exerts its effects by scavenging free radicals, chelating metal ions, and upregulating endogenous antioxidant enzymes like SOD and catalase through pathways involving Nrf2.

Screened PMID Records
6
Reported Benefits
Pending
Synergy Review
At a Glance
CategoryFruit
GroupCompound
Public Score StatusProvisional Moderate
Primary Keywordellagic acid from strawberries benefits
Ellagic Acid from Strawberries close-up macro showing natural texture and detail — rich in particularly with cyp1a1, cyp1a2, antioxidant
Ellagic Acid from Strawberries — botanical close-up

Reported Benefits (Provisional)

Antioxidant Protection
Neutralizes free radicals and reduces oxidative stress, protecting cellular structures and DNA.
Anti-Inflammatory Effects
Modulates inflammation pathways, supporting joint, cardiovascular, and metabolic health.
Anti-Cancer Potential
Inhibits proliferation of certain cancer cells and protects DNA from mutagenic damage.
Skin Health
Enhances elasticity, reduces signs of aging, and protects against UV-induced skin damage.
Cardiovascular Support
Improves endothelial function and lowers LDL cholesterol levels.
Gut Health
Acts as a prebiotic, encouraging the growth of beneficial gut bacteria.

Origin & History

Ellagic Acid from Strawberries growing in natural environment — natural habitat
Natural habitat

Ellagic acid is a bioactive polyphenol naturally found in strawberries, raspberries, pomegranates, and walnuts. It is celebrated for its potent antioxidant, anti-inflammatory, and anti-carcinogenic properties. Widely studied in modern pharmacology and nutraceutical science, ellagic acid plays a critical role in cellular defense, skin vitality, cardiovascular function, and microbiome modulation, making it a prized component in functional foods and wellness formulations.

Historically associated with longevity and cellular protection, ellagic acid has been revered in natural medicine for combating oxidative damage. In contemporary wellness, it is embraced as a phytochemical cornerstone in preventive nutrition and beauty-from-within formulations.Traditional Medicine

Research Narrative (Provisional)

Scientific validation includes antioxidant effects (PubMed: (see study_urls)), anti-cancer research (ScienceDirect: (see study_urls)), and dietary efficacy studies (ResearchGate: (see reference_urls)).

Preparation & Dosage

Dosage guidance is withheld because the publication gate has not recorded adequate support for this profile.

Nutritional Profile

- Polyphenols: Deliver antioxidant and anti-inflammatory protection. - Ellagitannins: Convert to ellagic acid and urolithins in the gut, enhancing systemic health. - Prebiotic Activity: Supports a healthy gut microbiome. - DNA Protective Properties: Shield genetic material from oxidative and environmental stressors.

Reported Mechanism (Provisional)

Mechanism of Action

Ellagic acid is released in the digestive system from ellagitannins, such as agrimoniin, found abundantly in strawberries. Its primary mechanisms involve direct free radical scavenging, neutralization of reactive oxygen species, and chelation of pro-oxidant metal ions like Fe²⁺. Furthermore, it upregulates antioxidant enzymes (e.g., superoxide dismutase, glutathione peroxidase, catalase) and activates the Nrf2 transcription factor, enhancing the body's intrinsic defense systems against oxidative stress.

Clinical Narrative (Provisional)

Scientific research on ellagic acid from strawberries has explored its antioxidant, anti-inflammatory, and anti-cancer potential, primarily in preclinical studies. These studies, including *in vitro* and *in vivo* animal models, validate its ability to neutralize free radicals and modulate inflammatory pathways. While promising, specific human clinical trials detailing sample sizes and precise outcomes for *isolated ellagic acid* in defined health conditions are broadly referenced for antioxidant and anti-cancer research without specific study data in the provided text. Further comprehensive human trials are needed to fully characterize its clinical efficacy and optimal dosages.

Also Known As

Ellagic acidEA

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These statements have not been evaluated by the Food and Drug Administration. This content is for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.
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