# Bur Marigold (Bidens tripartita)

**Canonical URL:** https://ingredients.hermeticasuperfoods.com/ingredients/bur-marigold-bidens-tripartita
**Data Source:** Hermetica Superfoods Ingredient Encyclopedia
**Updated:** 2026-03-15
**Evidence Score:** 6 / 10
**Category:** Flower
**Also Known As:** Bidens tripartita, Three-Lobed Bur-Marigold, Burr Marigold

## Overview

Bur Marigold contains flavonoids, phenolic acids, and polyacetylenes that contribute to its therapeutic effects. These compounds primarily reduce systemic [inflammation](/ingredients/condition/inflammation) by modulating cytokine pathways and exert [antimicrobial](/ingredients/condition/immune-support) action against various pathogens.

## Health Benefits

- Reduces systemic inflammation by modulating cytokine pathways through its flavonoid and phenolic acid content.
- Supports [immune system](/ingredients/condition/immune-support) function with antimicrobial properties from essential oils and flavonoids.
- Protects cells from oxidative damage due to the presence of potent [antioxidant](/ingredients/condition/antioxidant)s like quercetin and chlorogenic acid.
- Promotes skin healing and soothes irritation through its antimicrobial and [anti-inflammatory](/ingredients/condition/inflammation) compounds.
- Aids in gastrointestinal health by reducing inflammation and supporting a balanced [microbiome](/ingredients/condition/gut-health).

## Mechanism of Action

Bur Marigold exerts its [anti-inflammatory](/ingredients/condition/inflammation) effects primarily through flavonoids like luteolin and quercetin, alongside phenolic acids such as chlorogenic acid, which modulate cytokine pathways to reduce systemic inflammation. Its [antimicrobial](/ingredients/condition/immune-support) and antifungal actions are attributed to polyacetylenes, notably phenylheptatriyne, while potent antioxidants like flavonoids and phenolic acids protect cells by scavenging free radicals and reducing [oxidative stress](/ingredients/condition/antioxidant).

## Clinical Summary

Research on Bur Marigold primarily consists of in vitro and animal studies, which have supported its [anti-inflammatory](/ingredients/condition/inflammation), [antioxidant](/ingredients/condition/antioxidant), and antimicrobial properties. These studies suggest potential benefits in modulating [immune function](/ingredients/condition/immune-support) and treating skin conditions, attributed to its flavonoid and phenolic acid content. However, human clinical trials are currently limited, meaning the efficacy and safety in humans require further comprehensive investigation.

## Nutritional Profile

- Phytochemicals: Flavonoids (Quercetin, Kaempferol, Luteolin), Phenolic Acids (Chlorogenic Acid), Essential Oils.
- These bioactives collectively provide [antioxidant](/ingredients/condition/antioxidant), [anti-inflammatory](/ingredients/condition/inflammation), and [antimicrobial](/ingredients/condition/immune-support) properties.

## Dosage & Preparation

- Common forms: Tea (dried herb), tincture, extract, capsules, topical creams/ointments.
- For internal use: 500-1,000 mg of extract per day, or as a tea.
- For topical application: Apply creams or ointments containing Bur Marigold extract several times daily to affected skin areas.
- Dosage may vary based on extract concentration and specific health needs.

## Safety & Drug Interactions

While traditional uses suggest a generally safe profile, specific clinical data regarding the safety, side effects, and drug interactions of Bur Marigold in humans are very limited. Due to insufficient research, it is generally advised against use during pregnancy and lactation. Individuals with allergies to plants in the Asteraceae family should exercise caution.

## Scientific Research

Research, including in vitro and animal studies, supports Bur Marigold's [anti-inflammatory](/ingredients/condition/inflammation), [antioxidant](/ingredients/condition/antioxidant), and antimicrobial properties, attributed to its flavonoid and phenolic acid content. Studies have explored its potential in treating skin conditions and supporting [immune function](/ingredients/condition/immune-support). While promising, more human clinical trials are needed to confirm efficacy and optimal dosages.

## Historical & Cultural Context

Bur Marigold has been a valued herbal remedy for centuries in traditional European and Asian folk medicine. It was historically applied to treat conditions such as arthritis, respiratory infections, and gastrointestinal disorders, and used topically for wound healing. Its long-standing traditional use underscores its recognition for [anti-inflammatory](/ingredients/condition/inflammation) and [antimicrobial](/ingredients/condition/immune-support) properties.

## Synergistic Combinations

Role: Flower botanical (aroma + phytonutrient matrix)
Intention: Immune & [Inflammation](/ingredients/condition/inflammation)
Primary Pairings: - Ginger (Zingiber officinale)
- Chamomile (Matricaria chamomilla)
- Turmeric (Curcuma longa)
- Olive Oil (Olea europaea)

## Frequently Asked Questions

### What are the primary traditional uses of Bur Marigold?

Bur Marigold has traditionally been used in folk medicine for its purported antiseptic, anti-inflammatory, diuretic, and styptic properties. These applications primarily utilize the aerial parts of the plant, including the herb, flowers, and leaves.

### Which bioactive compounds are responsible for Bur Marigold's effects?

Key bioactive compounds include flavonoids like luteolin and quercetin, phenolic acids such as chlorogenic acid, and polyacetylenes, specifically phenylheptatriyne. These compounds collectively contribute to its anti-inflammatory, antioxidant, and antimicrobial activities.

### How does Bur Marigold reduce inflammation?

Bur Marigold reduces inflammation primarily through its flavonoid and phenolic acid content, which modulate cytokine pathways. By influencing these inflammatory mediators, the plant helps to alleviate systemic inflammation.

### What evidence exists for Bur Marigold's antimicrobial properties?

In vitro and animal studies support Bur Marigold's antimicrobial and antifungal properties, largely attributed to its essential oils, flavonoids, and particularly polyacetylenes like phenylheptatriyne. These compounds have shown efficacy against various pathogens.

### Is Bur Marigold extensively studied in humans?

While promising in vitro and animal studies explore its anti-inflammatory, antioxidant, and antimicrobial potential, clinical evidence in humans remains limited. More comprehensive human trials are needed to fully establish its efficacy and safety.

### Is Bur Marigold safe to use during pregnancy and breastfeeding?

Limited safety data exists for Bur Marigold use during pregnancy and breastfeeding, so it is generally recommended to avoid supplementation during these periods unless directed by a healthcare provider. Traditional use does not establish safety in these populations, and the herb's bioactive compounds may cross the placental barrier or be present in breast milk. Pregnant and nursing women should consult with their healthcare practitioner before using Bur Marigold supplements.

### Does Bur Marigold interact with medications like anticoagulants or immunosuppressants?

Bur Marigold's immune-stimulating and anti-inflammatory properties suggest potential interactions with immunosuppressant medications and blood-thinning drugs, though specific clinical interaction data is limited. The herb's flavonoid content may have mild anticoagulant effects, potentially additive with anticoagulant or antiplatelet medications. Anyone taking prescription medications, particularly immunosuppressants, anticoagulants, or antiplatelet agents, should consult their healthcare provider before supplementing with Bur Marigold.

### What is the most effective form of Bur Marigold—extract, dried herb, or tea?

Standardized extracts of Bur Marigold typically concentrate bioactive flavonoids and phenolic acids, potentially offering more consistent dosing than whole dried herb preparations. Herbal teas and infusions retain some beneficial compounds but may provide variable concentrations depending on steeping time and plant quality. The optimal form depends on intended use; extracts are preferred for systemic anti-inflammatory effects, while traditional teas may be suitable for general wellness support.

## References

Experience the healing power of Bur Marigold, nature’s anti-inflammatory and antimicrobial herb. Support your immune system, promote healthy skin, and relieve inflammation with this potent natural remedy. Shop now for Bur Marigold Extract to enhance your wellness routine.; | Sources: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566882/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310456/

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