Berberine Interactions

492 known interactions for Berberine. Click any interaction for the full evidence-based breakdown.

⚠️ Major (2)

Berberine + Glipizide🔴 CAUTION — Major interaction between Berberine and Glipizide. Avoid unless under direct medical supervision.
Berberine + Insulin (all forms)🔴 CAUTION — Major interaction between Berberine and Insulin (all forms). Avoid unless under direct medical supervision.

⚡ Moderate (5)

Berberine + Atorvastatin🟡 USE CAUTION — Berberine and Atorvastatin may interact. Talk to your doctor before combining.
Berberine + Cyclobenzaprine🟡 USE CAUTION — Berberine and Cyclobenzaprine may interact. Talk to your doctor before combining.
Berberine + Metformin🟡 USE CAUTION — Berberine and Metformin may interact. Talk to your doctor before combining.
Berberine + Simvastatin🟡 USE CAUTION — Berberine and Simvastatin may interact. Talk to your doctor before combining.
Berberine + Warfarin🟡 USE CAUTION — Berberine and Warfarin may interact. Talk to your doctor before combining.

✅ Safe (485)