SAFE — No Known Interaction
🟢 SAFE — St. Johns Wort and Sotalol can be taken together safely.
Evidence level: THEORETICAL
St. Johns Wort and Sotalol are generally considered safe to use together based on current medical evidence. No adverse interactions have been reported.
No clinically significant interaction between St. Johns Wort and Sotalol has been identified in medical literature or FDA drug labeling.
No interaction documented between St. Johns Wort and Sotalol. Always inform your healthcare provider about all supplements you take.
Take each at their normal times. St. Johns Wort — if it's hawthorn (a common cardiovascular botanical), it may have additive blood pressure and heart rate lowering effects with Sotalol. Monitor pulse and blood pressure. Stimulating botanicals like ephedra (ma huang) can counteract beta-blockers.
Higher risk for: those with asthma or COPD, bradycardia, diabetes (may mask hypoglycemia symptoms), elderly, concurrent calcium channel blocker use, or peripheral vascular disease.
Monitor blood pressure and heart rate when combining St. Johns Wort with Sotalol. Watch for: dizziness, lightheadedness (especially when standing up), fatigue, cold extremities, slow heartbeat, or swelling in ankles/feet. Check your blood pressure at home if possible. When to seek emergency help: Fainting, chest pain, heart rate below 50 bpm, severe dizziness, difficulty breathing, or allergic reactions (swelling of face, lips, or tongue).
No urgent need to discuss, but always keep your doctor informed of your full supplement and medication list. Say: "I take St. Johns Wort and Sotalol — is that OK?"
Safe combination at standard doses. Continue your medication as prescribed. Inform your doctor or pharmacist that you are using both, so they can monitor for any changes over time.
St. Johns Wort and Sotalol are generally considered safe to use together based on current medical evidence. No adverse interactions have been reported.
Take each at their normal times. St. Johns Wort — if it's hawthorn (a common cardiovascular botanical), it may have additive blood pressure and heart rate lowering effects with Sotalol. Monitor pulse and blood pressure. Stimulating botanicals like ephedra (ma huang) can counteract beta-blockers.
Monitor blood pressure and heart rate when combining St. Johns Wort with Sotalol. Watch for: dizziness, lightheadedness (especially when standing up), fatigue, cold extremities, slow heartbeat, or swelling in ankles/feet. Check your blood pressure at home if possible. When to seek emergency help: Fainting, chest pain, heart rate below 50 bpm, severe dizziness, difficulty breathing, or allergic reactions (swelling of face, lips, or tongue).
Safe combination at standard doses. Continue your medication as prescribed. Inform your doctor or pharmacist that you are using both, so they can monitor for any changes over time.
No urgent need to discuss, but always keep your doctor informed of your full supplement and medication list. Say: "I take St. Johns Wort and Sotalol — is that OK?"
Or browse the full interaction database (121,000+ pairs).