SAFE — No Known Interaction
🟢 SAFE — Fluoxetine and Andrographis can be taken together safely.
Evidence level: LIMITED
Fluoxetine and Andrographis are generally considered safe to use together. No adverse interactions have been reported in medical literature.
No clinically significant interaction between Fluoxetine and Andrographis has been identified in medical literature.
No interaction documented between Fluoxetine and Andrographis. Always inform your healthcare provider about everything you take.
Take Fluoxetine at the same time each day as prescribed. Andrographis can be taken at any convenient time — morning with breakfast is most common. Some botanicals (St. John's Wort especially) have serotonergic activity and must NOT be combined with SSRIs. If you notice increased drowsiness or agitation, shift the botanical to a different time or discuss discontinuation with your prescriber.
Higher risk for: elderly, those on multiple serotonergic drugs, people with liver impairment, CYP2D6 poor metabolizers, recent dose changes, or concurrent use of MAOIs or triptans.
Certain herbs can interact with serotonergic medications. Monitor for mood shifts, unusual drowsiness, or gastrointestinal changes when taking Fluoxetine with Andrographis. Red flags requiring immediate medical attention: confusion, rapid heartbeat, muscle rigidity, excessive sweating, tremors, or fever (possible serotonin-related reaction). Milder symptoms to track: changes in sleep quality, appetite changes, or mild nausea. Discuss all herbal products with your prescriber before combining.
No urgent discussion needed, but keep your provider informed. Say: "I take Fluoxetine alongside Andrographis — anything I should know?"
Safe combination at standard doses. Continue your medication as prescribed. Inform your doctor or pharmacist that you are using both, so they can monitor for any changes over time.
Fluoxetine and Andrographis are generally considered safe to use together. No adverse interactions have been reported in medical literature.
Take Fluoxetine at the same time each day as prescribed. Andrographis can be taken at any convenient time — morning with breakfast is most common. Some botanicals (St. John's Wort especially) have serotonergic activity and must NOT be combined with SSRIs. If you notice increased drowsiness or agitation, shift the botanical to a different time or discuss discontinuation with your prescriber.
Certain herbs can interact with serotonergic medications. Monitor for mood shifts, unusual drowsiness, or gastrointestinal changes when taking Fluoxetine with Andrographis. Red flags requiring immediate medical attention: confusion, rapid heartbeat, muscle rigidity, excessive sweating, tremors, or fever (possible serotonin-related reaction). Milder symptoms to track: changes in sleep quality, appetite changes, or mild nausea. Discuss all herbal products with your prescriber before combining.
Safe combination at standard doses. Continue your medication as prescribed. Inform your doctor or pharmacist that you are using both, so they can monitor for any changes over time.
No urgent discussion needed, but keep your provider informed. Say: "I take Fluoxetine alongside Andrographis — anything I should know?"
Or browse the full interaction database (121,000+ pairs).